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The consortium on vulnerability to externalizing disorders and addictions (c-VEDA): an accelerated longitudinal cohort of children and adolescents in India

The consortium on vulnerability to externalizing disorders and addictions (c-VEDA): an accelerated longitudinal cohort of children and adolescents in India
The consortium on vulnerability to externalizing disorders and addictions (c-VEDA): an accelerated longitudinal cohort of children and adolescents in India

The global burden of disease attributable to externalizing disorders such as alcohol misuse calls urgently for effective prevention and intervention. As our current knowledge is mainly derived from high-income countries such in Europe and North-America, it is difficult to address the wider socio-cultural, psychosocial context, and genetic factors in which risk and resilience are embedded in low- and medium-income countries. c-VEDA was established as the first and largest India-based multi-site cohort investigating the vulnerabilities for the development of externalizing disorders, addictions, and other mental health problems. Using a harmonised data collection plan coordinated with multiple cohorts in China, USA, and Europe, baseline data were collected from seven study sites between November 2016 and May 2019. Nine thousand and ten participants between the ages of 6 and 23 were assessed during this time, amongst which 1278 participants underwent more intensive assessments including MRI scans. Both waves of follow-ups have started according to the accelerated cohort structure with planned missingness design. Here, we present descriptive statistics on several key domains of assessments, and the full baseline dataset will be made accessible for researchers outside the consortium in September 2019. More details can be found on our website [cveda.org].

1359-4184
1618-1630
Zhang, Yuning
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Vaidya, Nilakshi
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Iyengar, Udita
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Sharma, Eesha
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Holla, Bharath
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Ahuja, Chirag K.
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Barker, Gareth J.
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Basu, Debasish
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Bharath, Rose Dawn
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Chakrabarti, Amit
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Desrivieres, Sylvane
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Elliott, Paul
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Fernandes, Gwen Sascha
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Gourisankar, Amritha
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Heron, Jon
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Hickman, Matthew
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Jacob, Preeti
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Jain, Sanjeev
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Jayarajan, Deepak
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Kalyanram, Kartik
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Kartik, Kamakshi
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Krishna, Murali
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Krishnaveni, Ghattu V.
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Kumar, Keshav
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Kumaran, Kalyanaraman
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Kuriyan, Rebecca
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Murthy, Pratima
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Orfanos, Dimitri Papadopoulos
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Purushottam, Meera
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Rangaswamy, Madhavi
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Kupard, Sunita Simon
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Singh, Lenin
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Singh, Roshan
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Subodh, B. N.
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Thennarasu, Kandavel
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Toledano, Mireille B.
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Varghese, Mathew
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Benegal, Vivek
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Schumann, Gunter
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The c-VEDA consortium
Zhang, Yuning
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Vaidya, Nilakshi
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Iyengar, Udita
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Sharma, Eesha
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Holla, Bharath
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Ahuja, Chirag K.
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Barker, Gareth J.
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Basu, Debasish
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Bharath, Rose Dawn
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Chakrabarti, Amit
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Desrivieres, Sylvane
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Elliott, Paul
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Fernandes, Gwen Sascha
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Gourisankar, Amritha
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Heron, Jon
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Hickman, Matthew
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Jacob, Preeti
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Jain, Sanjeev
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Jayarajan, Deepak
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Kalyanram, Kartik
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Kartik, Kamakshi
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Krishna, Murali
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Krishnaveni, Ghattu V.
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Kumar, Keshav
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Kumaran, Kalyanaraman
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Kuriyan, Rebecca
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Murthy, Pratima
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Orfanos, Dimitri Papadopoulos
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Purushottam, Meera
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Rangaswamy, Madhavi
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Kupard, Sunita Simon
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Singh, Lenin
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Singh, Roshan
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Subodh, B. N.
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Thennarasu, Kandavel
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Toledano, Mireille B.
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Varghese, Mathew
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Benegal, Vivek
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Schumann, Gunter
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Zhang, Yuning, Vaidya, Nilakshi, Iyengar, Udita, Sharma, Eesha, Holla, Bharath, Ahuja, Chirag K., Barker, Gareth J., Basu, Debasish, Bharath, Rose Dawn, Chakrabarti, Amit, Desrivieres, Sylvane, Elliott, Paul, Fernandes, Gwen Sascha, Gourisankar, Amritha, Heron, Jon, Hickman, Matthew, Jacob, Preeti, Jain, Sanjeev, Jayarajan, Deepak, Kalyanram, Kartik, Kartik, Kamakshi, Krishna, Murali, Krishnaveni, Ghattu V., Kumar, Keshav, Kumaran, Kalyanaraman, Kuriyan, Rebecca, Murthy, Pratima, Orfanos, Dimitri Papadopoulos, Purushottam, Meera, Rangaswamy, Madhavi, Kupard, Sunita Simon, Singh, Lenin, Singh, Roshan, Subodh, B. N., Thennarasu, Kandavel, Toledano, Mireille B., Varghese, Mathew, Benegal, Vivek and Schumann, Gunter , The c-VEDA consortium (2020) The consortium on vulnerability to externalizing disorders and addictions (c-VEDA): an accelerated longitudinal cohort of children and adolescents in India. Molecular Psychiatry, 25 (8), 1618-1630. (doi:10.1038/s41380-020-0656-1).

Record type: Article

Abstract

The global burden of disease attributable to externalizing disorders such as alcohol misuse calls urgently for effective prevention and intervention. As our current knowledge is mainly derived from high-income countries such in Europe and North-America, it is difficult to address the wider socio-cultural, psychosocial context, and genetic factors in which risk and resilience are embedded in low- and medium-income countries. c-VEDA was established as the first and largest India-based multi-site cohort investigating the vulnerabilities for the development of externalizing disorders, addictions, and other mental health problems. Using a harmonised data collection plan coordinated with multiple cohorts in China, USA, and Europe, baseline data were collected from seven study sites between November 2016 and May 2019. Nine thousand and ten participants between the ages of 6 and 23 were assessed during this time, amongst which 1278 participants underwent more intensive assessments including MRI scans. Both waves of follow-ups have started according to the accelerated cohort structure with planned missingness design. Here, we present descriptive statistics on several key domains of assessments, and the full baseline dataset will be made accessible for researchers outside the consortium in September 2019. More details can be found on our website [cveda.org].

Text
cVEDA_FinalSubmission - Accepted Manuscript
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More information

Accepted/In Press date: 17 January 2020
e-pub ahead of print date: 12 March 2020
Published date: 1 August 2020
Additional Information: Funding Information: Funding c-VEDA is jointly funded by the Indian Council for Medical Research (ICMR/MRC/3/M/2015-NCD-I) and the Newton Grant from the Medical Research Council (MR/N000390/1), United Kingdom. Publisher Copyright: © 2020, Springer Nature Limited.

Identifiers

Local EPrints ID: 437690
URI: http://eprints.soton.ac.uk/id/eprint/437690
ISSN: 1359-4184
PURE UUID: 92ff1b70-98b8-4e3a-af65-9a7d34c086a4
ORCID for Yuning Zhang: ORCID iD orcid.org/0000-0003-2225-6368

Catalogue record

Date deposited: 11 Feb 2020 17:35
Last modified: 02 Sep 2022 04:01

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Contributors

Author: Yuning Zhang ORCID iD
Author: Nilakshi Vaidya
Author: Udita Iyengar
Author: Eesha Sharma
Author: Bharath Holla
Author: Chirag K. Ahuja
Author: Gareth J. Barker
Author: Debasish Basu
Author: Rose Dawn Bharath
Author: Amit Chakrabarti
Author: Sylvane Desrivieres
Author: Paul Elliott
Author: Gwen Sascha Fernandes
Author: Amritha Gourisankar
Author: Jon Heron
Author: Matthew Hickman
Author: Preeti Jacob
Author: Sanjeev Jain
Author: Deepak Jayarajan
Author: Kartik Kalyanram
Author: Kamakshi Kartik
Author: Murali Krishna
Author: Ghattu V. Krishnaveni
Author: Keshav Kumar
Author: Rebecca Kuriyan
Author: Pratima Murthy
Author: Dimitri Papadopoulos Orfanos
Author: Meera Purushottam
Author: Madhavi Rangaswamy
Author: Sunita Simon Kupard
Author: Lenin Singh
Author: Roshan Singh
Author: B. N. Subodh
Author: Kandavel Thennarasu
Author: Mireille B. Toledano
Author: Mathew Varghese
Author: Vivek Benegal
Author: Gunter Schumann
Corporate Author: The c-VEDA consortium

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