Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study
Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study
Background: Diet diversity (DD) during infancy may prevent food allergies (FA), possibly by exposing the gastrointestinal microbiota to diverse foods and nutrients. Objective: To investigate the association between 4 different measures of DD during infancy and development of FA over the first decade of life. Methods: A birth cohort born between 2001 and 2002 were followed prospectively, providing information on sociodemographic, environmental, and dietary exposures. Information on age of introduction of a range of foods and food allergens was collected during infancy. Children were assessed for FA at 1, 2, 3, and 10 years. DD was defined using 4 measures in the first year of life: the World Health Organization definition of minimum DD at 6 months, as food diversity (FD) and fruit and vegetable diversity (FVD) at 3, 6, and 9 months, and as food allergen diversity (FAD) at 3, 6, 9, and 12 months. Results: A total of 969 pregnant women were recruited at 12-week gestation. A total of 900, 858, 891, and 827 offspring were assessed at 1, 2, 3, and 10 years. Univariate analysis showed that World Health Organization DD (P =.0047), FD (P =.0009), FAD (P =.0048), and FVD (P =.0174) at 6 months and FD (P =.0392), FAD (P =.0233), and FVD (.0163) at 9 months significantly reduced the odds of FA over the first decade of life. DD measures at 3 months were not associated with FA, but only 33% of the cohort had solid foods introduced by this age. Conclusion: Increased infant DD, as measured by 4 different methods, decreased the likelihood of developing FA.
Diet diversity, Dietary variety, Eczema, Food allergy prevention, Infant feeding
2017-2026
Venter, Carina
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Maslin, Kate
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Holloway, John W.
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Silveira, Lori J.
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Fleischer, David M.
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Dean, Taraneh
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Arshad, Syed
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June 2020
Venter, Carina
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Maslin, Kate
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Holloway, John W.
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Silveira, Lori J.
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Fleischer, David M.
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Dean, Taraneh
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Arshad, Syed
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Venter, Carina, Maslin, Kate, Holloway, John W., Silveira, Lori J., Fleischer, David M., Dean, Taraneh and Arshad, Syed
(2020)
Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study.
The Journal of Allergy and Clinical immunology: In Practice, 8 (6), .
(doi:10.1016/j.jaip.2020.01.029).
Abstract
Background: Diet diversity (DD) during infancy may prevent food allergies (FA), possibly by exposing the gastrointestinal microbiota to diverse foods and nutrients. Objective: To investigate the association between 4 different measures of DD during infancy and development of FA over the first decade of life. Methods: A birth cohort born between 2001 and 2002 were followed prospectively, providing information on sociodemographic, environmental, and dietary exposures. Information on age of introduction of a range of foods and food allergens was collected during infancy. Children were assessed for FA at 1, 2, 3, and 10 years. DD was defined using 4 measures in the first year of life: the World Health Organization definition of minimum DD at 6 months, as food diversity (FD) and fruit and vegetable diversity (FVD) at 3, 6, and 9 months, and as food allergen diversity (FAD) at 3, 6, 9, and 12 months. Results: A total of 969 pregnant women were recruited at 12-week gestation. A total of 900, 858, 891, and 827 offspring were assessed at 1, 2, 3, and 10 years. Univariate analysis showed that World Health Organization DD (P =.0047), FD (P =.0009), FAD (P =.0048), and FVD (P =.0174) at 6 months and FD (P =.0392), FAD (P =.0233), and FVD (.0163) at 9 months significantly reduced the odds of FA over the first decade of life. DD measures at 3 months were not associated with FA, but only 33% of the cohort had solid foods introduced by this age. Conclusion: Increased infant DD, as measured by 4 different methods, decreased the likelihood of developing FA.
Text
INPRACTICE-D-19-00772_R1 AAM pdf
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More information
Accepted/In Press date: 14 January 2020
e-pub ahead of print date: 28 January 2020
Published date: June 2020
Additional Information:
Funding Information:
The UK Food Standards Agency funded years 1-3 of the FAIR study (ref T0703). The 10-year follow-up was funded by the National Institute for Health Research, UK. The researchers acted independently of the funders.
Publisher Copyright:
© 2020 American Academy of Allergy, Asthma & Immunology
Keywords:
Diet diversity, Dietary variety, Eczema, Food allergy prevention, Infant feeding
Identifiers
Local EPrints ID: 437847
URI: http://eprints.soton.ac.uk/id/eprint/437847
ISSN: 2213-2198
PURE UUID: 125f907c-3a5c-43cf-a0f2-a6c4548226bc
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Date deposited: 20 Feb 2020 17:30
Last modified: 17 Mar 2024 05:18
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Contributors
Author:
Carina Venter
Author:
Kate Maslin
Author:
Lori J. Silveira
Author:
David M. Fleischer
Author:
Taraneh Dean
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