Simplicity in the design, operation, and applications of mechanically interlocked molecular machines
Simplicity in the design, operation, and applications of mechanically interlocked molecular machines
Mechanically interlocked molecules are perhaps best known as components of molecular machines, a view further reinforced by the Nobel Prize in 2016 to Stoddart and Sauvage. Despite amazing progress since these pioneers of the field reported the first examples of molecular shuttles, genuine applications of interlocked molecular machines remain elusive, and many barriers remain to be overcome before such molecular devices make the transition from impressive prototypes on the laboratory bench to useful products. Here, we discuss simplicity as a design principle that could be applied in the development of the next generation of molecular machines with a view to moving toward real-world applications of these intriguing systems in the longer term.
117-128
Heard, Andrew W.
f01893de-d170-48db-8804-b0a83bc4f192
Goldup, Stephen M.
0a93eedd-98bb-42c1-a963-e2815665e937
26 February 2020
Heard, Andrew W.
f01893de-d170-48db-8804-b0a83bc4f192
Goldup, Stephen M.
0a93eedd-98bb-42c1-a963-e2815665e937
Heard, Andrew W. and Goldup, Stephen M.
(2020)
Simplicity in the design, operation, and applications of mechanically interlocked molecular machines.
ACS Central Science, 6 (2), .
(doi:10.1021/acscentsci.9b01185).
Abstract
Mechanically interlocked molecules are perhaps best known as components of molecular machines, a view further reinforced by the Nobel Prize in 2016 to Stoddart and Sauvage. Despite amazing progress since these pioneers of the field reported the first examples of molecular shuttles, genuine applications of interlocked molecular machines remain elusive, and many barriers remain to be overcome before such molecular devices make the transition from impressive prototypes on the laboratory bench to useful products. Here, we discuss simplicity as a design principle that could be applied in the development of the next generation of molecular machines with a view to moving toward real-world applications of these intriguing systems in the longer term.
Text
2020 01 05 MS Central Science Outlook Heard
- Accepted Manuscript
Available under License Other.
More information
e-pub ahead of print date: 22 January 2020
Published date: 26 February 2020
Additional Information:
Funding Information:
S.M.G. and A.W.H. thank the European Research Council (Consolidator Grant agreement 724987) and University of Southampton for funding. S.M.G. is a Royal Society Wolfson Research Fellow.
Publisher Copyright:
Copyright © 2020 American Chemical Society.
Identifiers
Local EPrints ID: 437968
URI: http://eprints.soton.ac.uk/id/eprint/437968
ISSN: 2374-7943
PURE UUID: 1b28882b-df6e-4c71-9cc2-1617ae621e67
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Date deposited: 24 Feb 2020 17:32
Last modified: 16 Mar 2024 06:32
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Author:
Andrew W. Heard
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