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Memristive synapses connect brain and silicon spiking neurons

Memristive synapses connect brain and silicon spiking neurons
Memristive synapses connect brain and silicon spiking neurons
Brain function relies on circuits of spiking neurons with synapses playing the key role of merging transmission with memory storage and processing. Electronics has made important advances to emulate neurons and synapses and brain-computer interfacing concepts that interlink brain and brain-inspired devices are beginning to materialise. We report on memristive links between brain and silicon spiking neurons that emulate transmission and plasticity properties of real synapses. A memristor paired with a metal-thin film titanium oxide microelectrode connects a silicon neuron to a neuron of the rat hippocampus. Memristive plasticity accounts for modulation of connection strength, while transmission is mediated by weighted stimuli through the thin film oxide leading to responses that resemble excitatory postsynaptic potentials. The reverse brain-to-silicon link is established through a microelectrode-memristor pair. On these bases, we demonstrate a three-neuron brain-silicon network where memristive synapses undergo long-term potentiation or depression driven by neuronal firing rates.
2045-2322
Serb, Alexantrou
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Corna, Andrea
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George, Richard
a33e292a-9493-4076-b46f-fbd82ca6066d
Khiat, Ali
bf549ddd-5356-4a7d-9c12-eb6c0d904050
Rocchi, Federico
68503061-ec8a-4a08-8f9d-3c897324ba30
Reato, Marco
c3199581-eea2-4ad1-9fbe-431cfd8b1551
Maschietto, Marta
27355464-3836-4d74-9363-8b57220add30
Mayr, Christian
3d066b85-d564-414b-b0f6-876ce453166f
Indiveri, Giacomo
ce9f76c8-0416-4e2b-ab33-8a64fef04894
Vassanelli, Stefano
6476b466-51fb-447c-844d-6c35abaa1af7
Prodromakis, Themistoklis
d58c9c10-9d25-4d22-b155-06c8437acfbf
Serb, Alexantrou
30f5ec26-f51d-42b3-85fd-0325a27a792c
Corna, Andrea
f5147fe0-30d7-4a40-9f37-14cb6ec38154
George, Richard
a33e292a-9493-4076-b46f-fbd82ca6066d
Khiat, Ali
bf549ddd-5356-4a7d-9c12-eb6c0d904050
Rocchi, Federico
68503061-ec8a-4a08-8f9d-3c897324ba30
Reato, Marco
c3199581-eea2-4ad1-9fbe-431cfd8b1551
Maschietto, Marta
27355464-3836-4d74-9363-8b57220add30
Mayr, Christian
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Indiveri, Giacomo
ce9f76c8-0416-4e2b-ab33-8a64fef04894
Vassanelli, Stefano
6476b466-51fb-447c-844d-6c35abaa1af7
Prodromakis, Themistoklis
d58c9c10-9d25-4d22-b155-06c8437acfbf

Serb, Alexantrou, Corna, Andrea, George, Richard, Khiat, Ali, Rocchi, Federico, Reato, Marco, Maschietto, Marta, Mayr, Christian, Indiveri, Giacomo, Vassanelli, Stefano and Prodromakis, Themistoklis (2020) Memristive synapses connect brain and silicon spiking neurons. Scientific Reports, 10, [2590]. (doi:10.1038/s41598-020-58831-9).

Record type: Article

Abstract

Brain function relies on circuits of spiking neurons with synapses playing the key role of merging transmission with memory storage and processing. Electronics has made important advances to emulate neurons and synapses and brain-computer interfacing concepts that interlink brain and brain-inspired devices are beginning to materialise. We report on memristive links between brain and silicon spiking neurons that emulate transmission and plasticity properties of real synapses. A memristor paired with a metal-thin film titanium oxide microelectrode connects a silicon neuron to a neuron of the rat hippocampus. Memristive plasticity accounts for modulation of connection strength, while transmission is mediated by weighted stimuli through the thin film oxide leading to responses that resemble excitatory postsynaptic potentials. The reverse brain-to-silicon link is established through a microelectrode-memristor pair. On these bases, we demonstrate a three-neuron brain-silicon network where memristive synapses undergo long-term potentiation or depression driven by neuronal firing rates.

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VirtualBio_v42 - Accepted Manuscript
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Accepted/In Press date: 21 January 2020
e-pub ahead of print date: 25 February 2020
Published date: February 2020

Identifiers

Local EPrints ID: 437990
URI: http://eprints.soton.ac.uk/id/eprint/437990
ISSN: 2045-2322
PURE UUID: fec83801-2e5e-4759-a023-080fd92ac9d2
ORCID for Themistoklis Prodromakis: ORCID iD orcid.org/0000-0002-6267-6909

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Date deposited: 25 Feb 2020 17:31
Last modified: 18 Feb 2021 17:22

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Contributors

Author: Alexantrou Serb
Author: Andrea Corna
Author: Richard George
Author: Ali Khiat
Author: Federico Rocchi
Author: Marco Reato
Author: Marta Maschietto
Author: Christian Mayr
Author: Giacomo Indiveri
Author: Stefano Vassanelli

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