Enhanced interfacial adhesion and osseointegration of anodic TiO2 nanotube arrays on ultra-fine-grained titanium and underlying mechanisms
Enhanced interfacial adhesion and osseointegration of anodic TiO2 nanotube arrays on ultra-fine-grained titanium and underlying mechanisms
The poor adhesion of anodic TiO
2 nanotubes (TNTs) arrays on titanium (Ti) substrates adversely affects applications in many fields especially biomedical engineering. Herein, an efficient strategy is described to improve the adhesion strength of TNTs by performing grain refinement in the underlying Ti substrate via high-pressure torsion processing, as a larger number of grain boundaries can provide more interfacial mechanical anchorage. This process also improves the biocompatibility and osseointegration of TNTs by increasing the surface elastic modulus. The TNTs in length of 0.4 µm have significantly larger adhesion strength than the 2.0 µm long ones because the shorter TNTs experience less interfacial internal stress. However, post-anodization annealing reduces the fluorine concentration in TNTs and adhesion strength due to the formation of interfacial cavities during crystallization. The interfacial structure of TNTs/Ti system and the mechanism of adhesion failures are further investigated and discussed. Statement of Significance: Self-assembled TiO
2 nanotubes (TNTs) prepared by electrochemical anodization have a distinct morphology and superior properties, which are commonly used in photocatalytic systems, electronic devices, solar cells, sensors, as well as biomedical implants. However, the poor adhesion between the TNTs and Ti substrate has hampered wider applications. Here in this study, we describe an efficient strategy to improve the adhesion strength of TNTs by performing grain refinement in the underlying Ti substrate via high-pressure torsion (HPT) processing. The interfacial structure of TNTs/Ti system and the mechanism of adhesion failure are systematically studied and discussed. Our findings not only develop the knowledge of TNTs/Ti system, but also provide new insights into the design of Ti-based implants for orthopedic applications.
Adhesion strength, High-pressure torsion, Ti-based implants, TiO2 nanotubes, Ultra-fine-grained materials
360-375
Hu, Nan
958c9af0-da5f-43eb-b486-35e483a82feb
Wu, Yuzheng
2b59beef-44af-44c8-a7a4-dbca87bd2bc3
Xie, Lingxia
6fc9141c-42d5-41dd-962b-a95700d75f9f
Mohd Yusuf, Shahir Yasin Bin
5888c057-33da-45f3-a84d-95a291db8f34
Gao, Nong
9c1370f7-f4a9-4109-8a3a-4089b3baec21
Starink, Marco
fe61a323-4e0c-49c7-91f0-4450e1ec1e51
Tong, Liping
df65aa4e-1d5d-47a0-8e22-fbacd1da7e57
Chu, Paul K.
45d2a73e-c742-4f4f-b6d2-2c165b5e015a
Wang, Huaiyu
1e86fd87-7d0e-4e3c-8eb2-4af3d73c4fa6
1 April 2020
Hu, Nan
958c9af0-da5f-43eb-b486-35e483a82feb
Wu, Yuzheng
2b59beef-44af-44c8-a7a4-dbca87bd2bc3
Xie, Lingxia
6fc9141c-42d5-41dd-962b-a95700d75f9f
Mohd Yusuf, Shahir Yasin Bin
5888c057-33da-45f3-a84d-95a291db8f34
Gao, Nong
9c1370f7-f4a9-4109-8a3a-4089b3baec21
Starink, Marco
fe61a323-4e0c-49c7-91f0-4450e1ec1e51
Tong, Liping
df65aa4e-1d5d-47a0-8e22-fbacd1da7e57
Chu, Paul K.
45d2a73e-c742-4f4f-b6d2-2c165b5e015a
Wang, Huaiyu
1e86fd87-7d0e-4e3c-8eb2-4af3d73c4fa6
Hu, Nan, Wu, Yuzheng, Xie, Lingxia, Mohd Yusuf, Shahir Yasin Bin, Gao, Nong, Starink, Marco, Tong, Liping, Chu, Paul K. and Wang, Huaiyu
(2020)
Enhanced interfacial adhesion and osseointegration of anodic TiO2 nanotube arrays on ultra-fine-grained titanium and underlying mechanisms.
Acta Biomaterialia, 106, .
(doi:10.1016/j.actbio.2020.02.009).
Abstract
The poor adhesion of anodic TiO
2 nanotubes (TNTs) arrays on titanium (Ti) substrates adversely affects applications in many fields especially biomedical engineering. Herein, an efficient strategy is described to improve the adhesion strength of TNTs by performing grain refinement in the underlying Ti substrate via high-pressure torsion processing, as a larger number of grain boundaries can provide more interfacial mechanical anchorage. This process also improves the biocompatibility and osseointegration of TNTs by increasing the surface elastic modulus. The TNTs in length of 0.4 µm have significantly larger adhesion strength than the 2.0 µm long ones because the shorter TNTs experience less interfacial internal stress. However, post-anodization annealing reduces the fluorine concentration in TNTs and adhesion strength due to the formation of interfacial cavities during crystallization. The interfacial structure of TNTs/Ti system and the mechanism of adhesion failures are further investigated and discussed. Statement of Significance: Self-assembled TiO
2 nanotubes (TNTs) prepared by electrochemical anodization have a distinct morphology and superior properties, which are commonly used in photocatalytic systems, electronic devices, solar cells, sensors, as well as biomedical implants. However, the poor adhesion between the TNTs and Ti substrate has hampered wider applications. Here in this study, we describe an efficient strategy to improve the adhesion strength of TNTs by performing grain refinement in the underlying Ti substrate via high-pressure torsion (HPT) processing. The interfacial structure of TNTs/Ti system and the mechanism of adhesion failure are systematically studied and discussed. Our findings not only develop the knowledge of TNTs/Ti system, but also provide new insights into the design of Ti-based implants for orthopedic applications.
Text
Accepted manuscript
- Accepted Manuscript
More information
Accepted/In Press date: 6 February 2020
e-pub ahead of print date: 11 February 2020
Published date: 1 April 2020
Additional Information:
Funding Information:
The authors acknowledge financial support from the National Natural Science Foundation of China (No. 31922040 ), Shenzhen Science and Technology Research Funding (Nos. SGLH20180625144002074 and JCYJ20180507182637685 ), Youth Innovation Promotion Association of Chinese Academy of Sciences (No. 2017416 ), Leading Talents of Guangdong Province Program (No. 00201520 ), Shenzhen Peacock Program (No. KQTD2016030111500545 ), Science and Technology Service Network Initiative of Chinese Academy of Sciences (No. KFJ-STS-QYZX-035 ), China Postdoctoral Science Foundation (Nos. 2017LH039 and 2018M633184 ), Hong Kong Research Grants Council (RGC) General Research Funds (GRF) (No. CityU 11205617 ), as well as City University of Hong Kong Strategic Research Grant (SRG) (No. 7005264 ).
Publisher Copyright:
© 2020
Keywords:
Adhesion strength, High-pressure torsion, Ti-based implants, TiO2 nanotubes, Ultra-fine-grained materials
Identifiers
Local EPrints ID: 438023
URI: http://eprints.soton.ac.uk/id/eprint/438023
ISSN: 1742-7061
PURE UUID: d228b4c4-5fd5-40e3-85e9-1643486de1e4
Catalogue record
Date deposited: 26 Feb 2020 17:31
Last modified: 17 Mar 2024 05:21
Export record
Altmetrics
Contributors
Author:
Nan Hu
Author:
Yuzheng Wu
Author:
Lingxia Xie
Author:
Liping Tong
Author:
Paul K. Chu
Author:
Huaiyu Wang
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
