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How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes

How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes
How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes

This narrative review of the literature provides a summary and discussion of 25 years of research into the complex links between depression and diabetes. Systematic reviews have shown that depression occurs more frequently in people with type 1 or type 2 diabetes compared with people without diabetes. Currently, it remains unclear whether depression is also more common in people with impaired glucose metabolism or undiagnosed type 2 diabetes compared with people without diabetes. More prospective epidemiological research into the course of depression and an exploration of mechanisms in individuals with diabetes are needed. Depression in diabetes is associated with less optimal self-care behaviours, suboptimal glycaemic control, impaired quality of life, incident micro- and macrovascular diseases, and elevated mortality rates. Randomized controlled trails concluded that depression in diabetes can be treated with antidepressant medication, cognitive–behavioural therapy (individual, group-based or web-based), mindfulness-based cognitive therapy and stepped care. Although big strides forward have been made in the past 25 years, scientific evidence about depression in diabetes remains incomplete. Future studies should investigate mechanisms that link both conditions and test new diabetes-specific web- or app-based interventions for depression in diabetes. It is important to determine whether treatment or prevention of depression prevents future diabetes complications and lowers mortality rates.

0742-3071
383-392
Pouwer, F.
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Schram, M. T.
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Iversen, M. M.
859c3797-fe58-49df-be95-4f7df8c1b094
Nouwen, A.
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Holt, R. I.G.
d54202e1-fcf6-4a17-a320-9f32d7024393
Pouwer, F.
1bf90039-859a-487f-9276-3e8c103eeeef
Schram, M. T.
1c0b9303-a8ba-4117-9544-e72d601e310a
Iversen, M. M.
859c3797-fe58-49df-be95-4f7df8c1b094
Nouwen, A.
42fa5fa4-18ac-4c0e-b711-e6c4294dc51b
Holt, R. I.G.
d54202e1-fcf6-4a17-a320-9f32d7024393

Pouwer, F., Schram, M. T., Iversen, M. M., Nouwen, A. and Holt, R. I.G. (2020) How 25 years of psychosocial research has contributed to a better understanding of the links between depression and diabetes. Diabetic Medicine, 37 (3), 383-392. (doi:10.1111/dme.14227).

Record type: Editorial

Abstract

This narrative review of the literature provides a summary and discussion of 25 years of research into the complex links between depression and diabetes. Systematic reviews have shown that depression occurs more frequently in people with type 1 or type 2 diabetes compared with people without diabetes. Currently, it remains unclear whether depression is also more common in people with impaired glucose metabolism or undiagnosed type 2 diabetes compared with people without diabetes. More prospective epidemiological research into the course of depression and an exploration of mechanisms in individuals with diabetes are needed. Depression in diabetes is associated with less optimal self-care behaviours, suboptimal glycaemic control, impaired quality of life, incident micro- and macrovascular diseases, and elevated mortality rates. Randomized controlled trails concluded that depression in diabetes can be treated with antidepressant medication, cognitive–behavioural therapy (individual, group-based or web-based), mindfulness-based cognitive therapy and stepped care. Although big strides forward have been made in the past 25 years, scientific evidence about depression in diabetes remains incomplete. Future studies should investigate mechanisms that link both conditions and test new diabetes-specific web- or app-based interventions for depression in diabetes. It is important to determine whether treatment or prevention of depression prevents future diabetes complications and lowers mortality rates.

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Editorial special issue final - Accepted Manuscript
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Accepted/In Press date: 3 January 2020
e-pub ahead of print date: 7 January 2020
Published date: 1 March 2020
Additional Information: Funding Information: The opinions expressed here are those of the authors. They are not official statements of the PSAD (Psychosocial Aspects of Diabetes) study group or the EASD (European Association for the Study of Diabetes). Publisher Copyright: © 2020 Diabetes UK

Identifiers

Local EPrints ID: 438359
URI: http://eprints.soton.ac.uk/id/eprint/438359
ISSN: 0742-3071
PURE UUID: 1e61e9ca-2bb9-494f-8f5a-a6c4dfdb315e
ORCID for R. I.G. Holt: ORCID iD orcid.org/0000-0001-8911-6744

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Date deposited: 06 Mar 2020 17:33
Last modified: 17 Mar 2024 05:21

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Contributors

Author: F. Pouwer
Author: M. T. Schram
Author: M. M. Iversen
Author: A. Nouwen
Author: R. I.G. Holt ORCID iD

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