A design of flow electrolysis cell for ‘Home’ fabrication
A design of flow electrolysis cell for ‘Home’ fabrication
Despite extensive literature on organic electrosynthesis, it has never become a routine procedure in organic synthesis laboratories. One reason is certainly a lack of attention to the design of the cell used for the electrolysis; an appropriate cell is the dominant factor in determining the rate of conversion and the final conversion. Beaker cells predominate in published laboratory electrosyntheses but their use can limit reaction performance, and ease of scale-up, particularly where high rates of conversion are required without compromising selectivity for the desired product. This paper describes a simple design of a flow cell for operation in a recycle mode that is straightforward to fabricate and its performance is illustrated with anodic and cathodic electrosyntheses. The advantages of using turbulence promoters in the flow channel and a three dimensional electrode (reticulated vitreous carbon) are demonstrated. The cell allows the preparation of up to 5 mmol per hour of isolated product, and 20 mmol of product can be obtained over 4 h with high conversion of starting material. The cell design is readily scalable to enable the synthesis of larger quantities of product, and provides the capability to introduce a separator for organic electrosynthesis in a divided mode.
712-718
Folgueiras Amador, Ana
080c345d-0a05-406a-bf7c-1939ca9c0aaa
Teuten, Alexander E.
9ac179e7-8ced-4509-8c18-7d32d80afbdb
Pletcher, Derek
f22ebe69-b859-4a89-80b0-9e190e6f8f30
Brown, Richard C.D.
21ce697a-7c3a-480e-919f-429a3d8550f5
April 2020
Folgueiras Amador, Ana
080c345d-0a05-406a-bf7c-1939ca9c0aaa
Teuten, Alexander E.
9ac179e7-8ced-4509-8c18-7d32d80afbdb
Pletcher, Derek
f22ebe69-b859-4a89-80b0-9e190e6f8f30
Brown, Richard C.D.
21ce697a-7c3a-480e-919f-429a3d8550f5
Folgueiras Amador, Ana, Teuten, Alexander E., Pletcher, Derek and Brown, Richard C.D.
(2020)
A design of flow electrolysis cell for ‘Home’ fabrication.
Reaction Chemistry & Engineering, 5 (4), .
(doi:10.1039/D0RE00019A).
Abstract
Despite extensive literature on organic electrosynthesis, it has never become a routine procedure in organic synthesis laboratories. One reason is certainly a lack of attention to the design of the cell used for the electrolysis; an appropriate cell is the dominant factor in determining the rate of conversion and the final conversion. Beaker cells predominate in published laboratory electrosyntheses but their use can limit reaction performance, and ease of scale-up, particularly where high rates of conversion are required without compromising selectivity for the desired product. This paper describes a simple design of a flow cell for operation in a recycle mode that is straightforward to fabricate and its performance is illustrated with anodic and cathodic electrosyntheses. The advantages of using turbulence promoters in the flow channel and a three dimensional electrode (reticulated vitreous carbon) are demonstrated. The cell allows the preparation of up to 5 mmol per hour of isolated product, and 20 mmol of product can be obtained over 4 h with high conversion of starting material. The cell design is readily scalable to enable the synthesis of larger quantities of product, and provides the capability to introduce a separator for organic electrosynthesis in a divided mode.
Text
Flow Electrolysis Cell RCDBrown
- Accepted Manuscript
More information
Accepted/In Press date: 26 February 2020
e-pub ahead of print date: 27 February 2020
Published date: April 2020
Additional Information:
Funding Information:
The authors are grateful to Carlos Ponce de León and Luis Fernando Arenas (The University of Southampton) for useful discussion relating to the cell design and construction. The authors acknowledge financial support from EPSRC (Photo-Electro Programme Grant EP/P013341/1, EP/N509747/1 (studentship for AET, Project Reference 1796263) and EP/ K039466/1) and Cambridge Reactor Design Ltd. (studentship for AET).
Publisher Copyright:
© The Royal Society of Chemistry 2020.
Identifiers
Local EPrints ID: 438361
URI: http://eprints.soton.ac.uk/id/eprint/438361
ISSN: 2058-9883
PURE UUID: c073c8eb-66e4-474d-816e-1bd8ab7dde24
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Date deposited: 06 Mar 2020 17:33
Last modified: 17 Mar 2024 05:23
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Author:
Ana Folgueiras Amador
Author:
Alexander E. Teuten
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