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Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence

Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence
Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence
The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.
Allergic Rhinitis and Its Impact on Asthma, Allergic rhinitis, Development and Evaluation, Grading of Recommendations Assessment, guidelines, real-world evidence
0091-6749
70-80.e3
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Zuberbier, Torsten
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Bousquet, Jean, Schunemann, Holger J., Togias, Akdis, Bachert, Claus, Erhola, Martina, Hellings, Peter W., Klimek, Ludger, Pfaar, Oliver, Wallace, Dana, Ansotegui, Ignacio, Agache, Ioana, Bedbrook, Anna, Bergmann, Karl-Christian, Bewick, Mike, Bonniaud, Philippe, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis-Philippe, Brozek, Jan, Brusselle, Guy, Calderon, Moises A., Canonica, Walter G., Caraballo, Luis, Cardona, Vicky, Casale, Thomas, Cecchi, Lorenzo, Chu, Derek K., Costa, Elisio M., Cruz, Alvaro A., Czarlewski, Wienczyslawa, D'Amato, Gennaro, Devillier, Philippe, Dykewicz, Mark, Ebisawa, Motohiro, Fauquert, Jean-Louis, Fokkens, Wytske J., Fonseca, Joao A., Fontaine, Jean-Francois, Gemicioglu, Bilun, van Wijk, Roy Gerth, Haahtela, Tari, Halken, Susanne, Ierodiakonou, Despo, Iinuma, Tomohisa, Ivancevich, Juan-Carlos, Jutel, Marek, Kaidashev, Igor, Khaitov, Musa, Kalayci, Omer, Tebbe, Jorg Kleine, Kowalski, Marek L., Kuna, Piotr, Kvedariene, Violeta, La Grutta, Stefania, Larenas-Linemann, Desiree, Lau, Susanne, Laune, Daniel, Le, Lan, Lieberman, Philipp, Carlsen, Karin C. Lodrup, Lourenco, Olga, Marien, Gert, Carreiro-Martins, Pedro, Melen, Erik, Menditto, Enrica, Neffen, Hugo, Mercier, Gregoire, Mosgues, Ralph, Mullol, Joaquim, Muraro, Antonella, Namazova, Leyla, Novellino, Ettore, O'Hehir, Robyn, Okamoto, Yoshitaka, Ohta, Ken, Park, Hae Sim, Panzner, Petr, Passalacqua, Giovanni, Nhan Pham-Thi, , Price, David, Roberts, Graham, Roche, Nicolas, Rolland, Christine, Rosario, Nelson, Ryan, Dermot, Samolinski, Boleslaw, Sanchez-Borges, Mario, Scadding, Glenis K., Shamji, Mohamed H., Sheikh, Aziz, Bom, Ana-Maria Todo, Toppila-Salmi, Sanna, Tsiligianni, Ioana, Valentin-Rostan, Marylin, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria-Teresa, Walker, Samantha, Waserman, Susan, Yorgancioglu, Arzu and Zuberbier, Torsten (2020) Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. Journal of Allergy and Clinical Immunology, 145 (1), 70-80.e3. (doi:10.1016/j.jaci.2019.06.049).

Record type: Review

Abstract

The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.

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More information

Accepted/In Press date: 12 June 2019
e-pub ahead of print date: 15 October 2019
Published date: January 2020
Keywords: Allergic Rhinitis and Its Impact on Asthma, Allergic rhinitis, Development and Evaluation, Grading of Recommendations Assessment, guidelines, real-world evidence

Identifiers

Local EPrints ID: 438524
URI: http://eprints.soton.ac.uk/id/eprint/438524
ISSN: 0091-6749
PURE UUID: 57bd01c6-077e-4e16-952c-e8c22f433404
ORCID for Graham Roberts: ORCID iD orcid.org/0000-0003-2252-1248

Catalogue record

Date deposited: 12 Mar 2020 17:34
Last modified: 26 Nov 2021 02:49

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Contributors

Author: Jean Bousquet
Author: Holger J. Schunemann
Author: Akdis Togias
Author: Claus Bachert
Author: Martina Erhola
Author: Peter W. Hellings
Author: Ludger Klimek
Author: Oliver Pfaar
Author: Dana Wallace
Author: Ignacio Ansotegui
Author: Ioana Agache
Author: Anna Bedbrook
Author: Karl-Christian Bergmann
Author: Mike Bewick
Author: Philippe Bonniaud
Author: Sinthia Bosnic-Anticevich
Author: Isabelle Bosse
Author: Jacques Bouchard
Author: Louis-Philippe Boulet
Author: Jan Brozek
Author: Guy Brusselle
Author: Moises A. Calderon
Author: Walter G. Canonica
Author: Luis Caraballo
Author: Vicky Cardona
Author: Thomas Casale
Author: Lorenzo Cecchi
Author: Derek K. Chu
Author: Elisio M. Costa
Author: Alvaro A. Cruz
Author: Wienczyslawa Czarlewski
Author: Gennaro D'Amato
Author: Philippe Devillier
Author: Mark Dykewicz
Author: Motohiro Ebisawa
Author: Jean-Louis Fauquert
Author: Wytske J. Fokkens
Author: Joao A. Fonseca
Author: Jean-Francois Fontaine
Author: Bilun Gemicioglu
Author: Roy Gerth van Wijk
Author: Tari Haahtela
Author: Susanne Halken
Author: Despo Ierodiakonou
Author: Tomohisa Iinuma
Author: Juan-Carlos Ivancevich
Author: Marek Jutel
Author: Igor Kaidashev
Author: Musa Khaitov
Author: Omer Kalayci
Author: Jorg Kleine Tebbe
Author: Marek L. Kowalski
Author: Piotr Kuna
Author: Violeta Kvedariene
Author: Stefania La Grutta
Author: Desiree Larenas-Linemann
Author: Susanne Lau
Author: Daniel Laune
Author: Lan Le
Author: Philipp Lieberman
Author: Karin C. Lodrup Carlsen
Author: Olga Lourenco
Author: Gert Marien
Author: Pedro Carreiro-Martins
Author: Erik Melen
Author: Enrica Menditto
Author: Hugo Neffen
Author: Gregoire Mercier
Author: Ralph Mosgues
Author: Joaquim Mullol
Author: Antonella Muraro
Author: Leyla Namazova
Author: Ettore Novellino
Author: Robyn O'Hehir
Author: Yoshitaka Okamoto
Author: Ken Ohta
Author: Hae Sim Park
Author: Petr Panzner
Author: Giovanni Passalacqua
Author: Nhan Pham-Thi
Author: David Price
Author: Graham Roberts ORCID iD
Author: Nicolas Roche
Author: Christine Rolland
Author: Nelson Rosario
Author: Dermot Ryan
Author: Boleslaw Samolinski
Author: Mario Sanchez-Borges
Author: Glenis K. Scadding
Author: Mohamed H. Shamji
Author: Aziz Sheikh
Author: Ana-Maria Todo Bom
Author: Sanna Toppila-Salmi
Author: Ioana Tsiligianni
Author: Marylin Valentin-Rostan
Author: Arunas Valiulis
Author: Erkka Valovirta
Author: Maria-Teresa Ventura
Author: Samantha Walker
Author: Susan Waserman
Author: Arzu Yorgancioglu
Author: Torsten Zuberbier

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