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Automatic contouring of soft organs for image-guided prostate radiotherapy

Automatic contouring of soft organs for image-guided prostate radiotherapy
Automatic contouring of soft organs for image-guided prostate radiotherapy
Results: MRI delineation reduced intra-observer variability compared to pCT. DIR-whole resulted in GTVs significantly closer to the GS as determined by multiple positional metrics in comparison with CT-only delineation (normalised results are shown in Figure 1). The mean Dice Similarity Coefficient was 0.6 and 0.72 for pCT and DIR-whole respectively with p= 0.019. Use of MRI-D with Rigid-ROI or DIR-ROI provided no advantage over CT-only delineation.

Conclusion: In the absence of dedicated MRI-RT, image registration software can aid the integration of MRI-D into the treatment pathway. MRI-D is most accurately integrated into the radiotherapy planning pathway when contours are transposed to pCT with DIR over the whole patient.
0167-8140
S895-S896
Cai, Xiaohao
de483445-45e9-4b21-a4e8-b0427fc72cee
Schönlieb, Carola Bibiane
655fcff7-df67-4700-ac57-c318656c4722
Lee, Juheon
bcc7dd3e-6eef-418a-a735-8bb38d51476f
Scaife, J.
24fdad0f-8011-46e5-9a2a-3c0f30503840
Harrison, Karl
6a02690d-d0d5-4d5f-a3e9-a6a0edd5c623
Sutcliffe, Michael
5117fd2a-e0b0-46ff-bbac-3758fabfa955
Parker, M. Andy
c65b0366-a89e-41db-a9e1-09bb3cde0f4d
Burnet, Neil G.
628e3a34-5db9-436f-836c-04169c3f8cde
Cai, Xiaohao
de483445-45e9-4b21-a4e8-b0427fc72cee
Schönlieb, Carola Bibiane
655fcff7-df67-4700-ac57-c318656c4722
Lee, Juheon
bcc7dd3e-6eef-418a-a735-8bb38d51476f
Scaife, J.
24fdad0f-8011-46e5-9a2a-3c0f30503840
Harrison, Karl
6a02690d-d0d5-4d5f-a3e9-a6a0edd5c623
Sutcliffe, Michael
5117fd2a-e0b0-46ff-bbac-3758fabfa955
Parker, M. Andy
c65b0366-a89e-41db-a9e1-09bb3cde0f4d
Burnet, Neil G.
628e3a34-5db9-436f-836c-04169c3f8cde

Cai, Xiaohao, Schönlieb, Carola Bibiane, Lee, Juheon, Scaife, J., Harrison, Karl, Sutcliffe, Michael, Parker, M. Andy and Burnet, Neil G. (2016) Automatic contouring of soft organs for image-guided prostate radiotherapy. Radiotherapy and Oncology, 119 (Supplement 1), S895-S896. (doi:10.1016/S0167-8140(16)33144-9).

Record type: Meeting abstract

Abstract

Results: MRI delineation reduced intra-observer variability compared to pCT. DIR-whole resulted in GTVs significantly closer to the GS as determined by multiple positional metrics in comparison with CT-only delineation (normalised results are shown in Figure 1). The mean Dice Similarity Coefficient was 0.6 and 0.72 for pCT and DIR-whole respectively with p= 0.019. Use of MRI-D with Rigid-ROI or DIR-ROI provided no advantage over CT-only delineation.

Conclusion: In the absence of dedicated MRI-RT, image registration software can aid the integration of MRI-D into the treatment pathway. MRI-D is most accurately integrated into the radiotherapy planning pathway when contours are transposed to pCT with DIR over the whole patient.

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Published date: 1 April 2016

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Local EPrints ID: 438757
URI: http://eprints.soton.ac.uk/id/eprint/438757
ISSN: 0167-8140
PURE UUID: 2c53f3ee-dc4b-4d2b-8f9e-f0dd97fce1b5

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Date deposited: 24 Mar 2020 17:30
Last modified: 09 Oct 2020 16:38

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Contributors

Author: Xiaohao Cai
Author: Carola Bibiane Schönlieb
Author: Juheon Lee
Author: J. Scaife
Author: Karl Harrison
Author: Michael Sutcliffe
Author: M. Andy Parker
Author: Neil G. Burnet

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