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AT-CuAAC synthesis of mechanically interlocked oligonucleotides

AT-CuAAC synthesis of mechanically interlocked oligonucleotides
AT-CuAAC synthesis of mechanically interlocked oligonucleotides
We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.
0002-7863
5985-5990
Acevedo-Jake, Amanda
648b12e3-763b-4e0b-bf33-abf4f85be1ef
Ball, Andrew T
9e437c52-aaa3-4684-a8cc-6eac3faf56ed
Galli, Marzia
951df54d-479d-4186-98ec-ac4c68d9c2d0
Kukwikila, Nsimba M
98905496-cea6-44fe-9999-a26fb0b72cc9
Denis, Mathieu AS
14de88e5-03ef-4666-b3cf-345ac2754e02
Singleton, Daniel
6c251bf3-8ca7-478d-8870-b39705b1c5fc
Tavassoli, Ali
d561cf8f-2669-46b5-b6e1-2016c85d63b2
Goldup, Stephen
0a93eedd-98bb-42c1-a963-e2815665e937
Acevedo-Jake, Amanda
648b12e3-763b-4e0b-bf33-abf4f85be1ef
Ball, Andrew T
9e437c52-aaa3-4684-a8cc-6eac3faf56ed
Galli, Marzia
951df54d-479d-4186-98ec-ac4c68d9c2d0
Kukwikila, Nsimba M
98905496-cea6-44fe-9999-a26fb0b72cc9
Denis, Mathieu AS
14de88e5-03ef-4666-b3cf-345ac2754e02
Singleton, Daniel
6c251bf3-8ca7-478d-8870-b39705b1c5fc
Tavassoli, Ali
d561cf8f-2669-46b5-b6e1-2016c85d63b2
Goldup, Stephen
0a93eedd-98bb-42c1-a963-e2815665e937

Acevedo-Jake, Amanda, Ball, Andrew T, Galli, Marzia, Kukwikila, Nsimba M, Denis, Mathieu AS, Singleton, Daniel, Tavassoli, Ali and Goldup, Stephen (2020) AT-CuAAC synthesis of mechanically interlocked oligonucleotides. Journal of the American Chemical Society, 142 (13), 5985-5990. (doi:10.1021/jacs.0c01670).

Record type: Article

Abstract

We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.

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MS Acevedo RotDNA JACS - Accepted Manuscript
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More information

Accepted/In Press date: 10 March 2020
e-pub ahead of print date: 10 March 2020
Published date: 1 April 2020

Identifiers

Local EPrints ID: 439012
URI: http://eprints.soton.ac.uk/id/eprint/439012
ISSN: 0002-7863
PURE UUID: c7e0b7fa-4564-4f84-aa55-cee57c8d10b9
ORCID for Ali Tavassoli: ORCID iD orcid.org/0000-0002-7420-5063
ORCID for Stephen Goldup: ORCID iD orcid.org/0000-0003-3781-0464

Catalogue record

Date deposited: 31 Mar 2020 16:31
Last modified: 17 Mar 2024 05:26

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Contributors

Author: Amanda Acevedo-Jake
Author: Andrew T Ball
Author: Marzia Galli
Author: Nsimba M Kukwikila
Author: Mathieu AS Denis
Author: Daniel Singleton
Author: Ali Tavassoli ORCID iD
Author: Stephen Goldup ORCID iD

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