The University of Southampton
University of Southampton Institutional Repository

AT-CuAAC synthesis of mechanically interlocked oligonucleotides

AT-CuAAC synthesis of mechanically interlocked oligonucleotides
AT-CuAAC synthesis of mechanically interlocked oligonucleotides
We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.
0002-7863
5985-5990
Acevedo-Jake, Amanda
648b12e3-763b-4e0b-bf33-abf4f85be1ef
Ball, Andrew T
9e437c52-aaa3-4684-a8cc-6eac3faf56ed
Galli, Marzia
951df54d-479d-4186-98ec-ac4c68d9c2d0
Kukwikila, Nsimba M
98905496-cea6-44fe-9999-a26fb0b72cc9
Denis, Mathieu AS
14de88e5-03ef-4666-b3cf-345ac2754e02
Singleton, Daniel
6c251bf3-8ca7-478d-8870-b39705b1c5fc
Tavassoli, Ali
d561cf8f-2669-46b5-b6e1-2016c85d63b2
Goldup, Stephen
0a93eedd-98bb-42c1-a963-e2815665e937
Acevedo-Jake, Amanda
648b12e3-763b-4e0b-bf33-abf4f85be1ef
Ball, Andrew T
9e437c52-aaa3-4684-a8cc-6eac3faf56ed
Galli, Marzia
951df54d-479d-4186-98ec-ac4c68d9c2d0
Kukwikila, Nsimba M
98905496-cea6-44fe-9999-a26fb0b72cc9
Denis, Mathieu AS
14de88e5-03ef-4666-b3cf-345ac2754e02
Singleton, Daniel
6c251bf3-8ca7-478d-8870-b39705b1c5fc
Tavassoli, Ali
d561cf8f-2669-46b5-b6e1-2016c85d63b2
Goldup, Stephen
0a93eedd-98bb-42c1-a963-e2815665e937

Acevedo-Jake, Amanda, Ball, Andrew T, Galli, Marzia, Kukwikila, Nsimba M, Denis, Mathieu AS, Singleton, Daniel, Tavassoli, Ali and Goldup, Stephen (2020) AT-CuAAC synthesis of mechanically interlocked oligonucleotides. Journal of the American Chemical Society, 142 (13), 5985-5990. (doi:10.1021/jacs.0c01670).

Record type: Article

Abstract

We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.

Text
MS Acevedo RotDNA JACS - Accepted Manuscript
Download (320kB)

More information

Accepted/In Press date: 10 March 2020
e-pub ahead of print date: 10 March 2020
Published date: 1 April 2020

Identifiers

Local EPrints ID: 439012
URI: http://eprints.soton.ac.uk/id/eprint/439012
ISSN: 0002-7863
PURE UUID: c7e0b7fa-4564-4f84-aa55-cee57c8d10b9
ORCID for Ali Tavassoli: ORCID iD orcid.org/0000-0002-7420-5063
ORCID for Stephen Goldup: ORCID iD orcid.org/0000-0003-3781-0464

Catalogue record

Date deposited: 31 Mar 2020 16:31
Last modified: 28 Apr 2022 05:53

Export record

Altmetrics

Contributors

Author: Amanda Acevedo-Jake
Author: Andrew T Ball
Author: Marzia Galli
Author: Nsimba M Kukwikila
Author: Mathieu AS Denis
Author: Daniel Singleton
Author: Ali Tavassoli ORCID iD
Author: Stephen Goldup ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×