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Microbes central to human reproduction

Microbes central to human reproduction
Microbes central to human reproduction

As studies uncover the breadth of microbes associated with human life, opportunities will emerge to manipulate and augment their functions in ways that improve health and longevity. From involvement in the complexities of reproduction and fetal/infant development, to delaying the onset of disease, and indeed countering many maladies, microbes offer hope for human well-being. Evidence is emerging to suggest that microbes may play a beneficial role in body sites traditionally viewed as being sterile. Although further evidence is required, we propose that much of medical dogma is about to change significantly through recognition and understanding of these hitherto unrecognized microbe-host interactions. A meeting of the International Scientific Association for Probiotics and Prebiotics held in Aberdeen, Scotland (June 2014), presented new views and challenged established concepts on the role of microbes in reproduction and health of the mother and infant. This article summarizes some of the main aspects of these discussions.

Female, Host-Pathogen Interactions/physiology, Humans/microbiology, Infant, Microbiota/physiology, Mothers, Prebiotics, Probiotics, Reproduction, Scotland
1046-7408
1-11
Reid, Gregor
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Brigidi, Patrizia
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Burton, Jeremy P
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Contractor, Nikhat
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Duncan, Sylvia
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Fargier, Emilie
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Hill, Colin
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Lebeer, Sarah
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Martín, Rocio
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McBain, Andrew J
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Mor, Gil
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O'Neill, Catherine
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Rodríguez, Juan Miguel
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Swann, Jonathan
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van Hemert, Saskia
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Ansell, Juliett
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Reid, Gregor
e44904d2-b02c-4e89-8be5-1939de379d73
Brigidi, Patrizia
acba7440-3a5f-4e6c-8168-9a62f9556ed1
Burton, Jeremy P
46c57b31-047f-4429-9bf7-ebc4e38d9f9b
Contractor, Nikhat
d1ac55ef-0158-4ea4-9cc5-94f2cbd90a77
Duncan, Sylvia
d884828e-e972-48d6-b28f-04cee8f7c846
Fargier, Emilie
83d47d60-3d14-47ac-bf05-f259783f8839
Hill, Colin
3865af43-3708-4b0d-a6f7-98f852ed56f0
Lebeer, Sarah
bd7e8644-76cc-480e-b374-39ce7c4e92fa
Martín, Rocio
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McBain, Andrew J
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Mor, Gil
38aec9f2-f02d-4c54-8c0f-45bef3411ede
O'Neill, Catherine
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Rodríguez, Juan Miguel
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Swann, Jonathan
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van Hemert, Saskia
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Ansell, Juliett
353d240d-b1cd-40b1-9f4a-e8954a92ef7c

Reid, Gregor, Brigidi, Patrizia, Burton, Jeremy P, Contractor, Nikhat, Duncan, Sylvia, Fargier, Emilie, Hill, Colin, Lebeer, Sarah, Martín, Rocio, McBain, Andrew J, Mor, Gil, O'Neill, Catherine, Rodríguez, Juan Miguel, Swann, Jonathan, van Hemert, Saskia and Ansell, Juliett (2015) Microbes central to human reproduction. American Journal of Reproductive Immunology, 73 (1), 1-11. (doi:10.1111/aji.12319).

Record type: Review

Abstract

As studies uncover the breadth of microbes associated with human life, opportunities will emerge to manipulate and augment their functions in ways that improve health and longevity. From involvement in the complexities of reproduction and fetal/infant development, to delaying the onset of disease, and indeed countering many maladies, microbes offer hope for human well-being. Evidence is emerging to suggest that microbes may play a beneficial role in body sites traditionally viewed as being sterile. Although further evidence is required, we propose that much of medical dogma is about to change significantly through recognition and understanding of these hitherto unrecognized microbe-host interactions. A meeting of the International Scientific Association for Probiotics and Prebiotics held in Aberdeen, Scotland (June 2014), presented new views and challenged established concepts on the role of microbes in reproduction and health of the mother and infant. This article summarizes some of the main aspects of these discussions.

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aji.12319 - Version of Record
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More information

Accepted/In Press date: 18 August 2014
e-pub ahead of print date: 24 September 2014
Published date: January 2015
Keywords: Female, Host-Pathogen Interactions/physiology, Humans/microbiology, Infant, Microbiota/physiology, Mothers, Prebiotics, Probiotics, Reproduction, Scotland

Identifiers

Local EPrints ID: 439407
URI: http://eprints.soton.ac.uk/id/eprint/439407
ISSN: 1046-7408
PURE UUID: 29d5ff86-2649-438a-9346-3a476d8dbf04
ORCID for Jonathan Swann: ORCID iD orcid.org/0000-0002-6485-4529

Catalogue record

Date deposited: 21 Apr 2020 16:52
Last modified: 17 Mar 2024 04:00

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Contributors

Author: Gregor Reid
Author: Patrizia Brigidi
Author: Jeremy P Burton
Author: Nikhat Contractor
Author: Sylvia Duncan
Author: Emilie Fargier
Author: Colin Hill
Author: Sarah Lebeer
Author: Rocio Martín
Author: Andrew J McBain
Author: Gil Mor
Author: Catherine O'Neill
Author: Juan Miguel Rodríguez
Author: Jonathan Swann ORCID iD
Author: Saskia van Hemert
Author: Juliett Ansell

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