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Incidence of myocardial infarction and associated mortality varies by latitude and season: findings from a Swedish Registry Study

Incidence of myocardial infarction and associated mortality varies by latitude and season: findings from a Swedish Registry Study
Incidence of myocardial infarction and associated mortality varies by latitude and season: findings from a Swedish Registry Study
Background
We investigated whether the incidence of death following myocardial infarction (MI) varied by season and latitude in the Swedish population.

Methods
We studied deaths following MI from January 1987 to December 2009, using the Swedish National Cause of Death Register. County of residence was used to determine latitude and population density. An extension of Poisson regression was used to study the relationship between risk of death following MI with age, latitude, time (from 1987), population density and calendar days.

Results
Over the study period, there was a secular decrease in the incidence of MI-related death. In men, MI-related death incidence increased by 1.3% [95% confidence interval (CI) = 1.1–1.5] per degree of latitude (northwards). In women, MI-related death incidence increased by 0.6% (95% CI = 0.4–0.9) per degree of latitude. There was seasonal variation in the risk of MI-related death with peak values in the late winter and a nadir in the summer months in both the north and the south of Sweden. Findings were similar with incident MI as the outcome.

Conclusions
The incidence of MI-related death varied markedly by season and latitude in Sweden, with summer months and more southerly latitude associated with lower rates than winter months and more northerly latitude.

1741-3842
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Lorentzen, Mattias
72997ee0-d7ba-42b1-912e-f60414366449
Kanis, John A.
f1621d8d-8afb-4d97-9679-2165d88a344d
McCloskey, Eugene
3a2fac33-b400-4ae3-a212-04c3c3d2a517
Johansson, Helena
04f12338-4dd1-437b-b9bc-e0884130c215
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Lorentzen, Mattias
72997ee0-d7ba-42b1-912e-f60414366449
Kanis, John A.
f1621d8d-8afb-4d97-9679-2165d88a344d
McCloskey, Eugene
3a2fac33-b400-4ae3-a212-04c3c3d2a517
Johansson, Helena
04f12338-4dd1-437b-b9bc-e0884130c215

Harvey, Nicholas, Lorentzen, Mattias, Kanis, John A., McCloskey, Eugene and Johansson, Helena (2019) Incidence of myocardial infarction and associated mortality varies by latitude and season: findings from a Swedish Registry Study. Journal of Public Health. (doi:10.1093/pubmed/fdz131).

Record type: Article

Abstract

Background
We investigated whether the incidence of death following myocardial infarction (MI) varied by season and latitude in the Swedish population.

Methods
We studied deaths following MI from January 1987 to December 2009, using the Swedish National Cause of Death Register. County of residence was used to determine latitude and population density. An extension of Poisson regression was used to study the relationship between risk of death following MI with age, latitude, time (from 1987), population density and calendar days.

Results
Over the study period, there was a secular decrease in the incidence of MI-related death. In men, MI-related death incidence increased by 1.3% [95% confidence interval (CI) = 1.1–1.5] per degree of latitude (northwards). In women, MI-related death incidence increased by 0.6% (95% CI = 0.4–0.9) per degree of latitude. There was seasonal variation in the risk of MI-related death with peak values in the late winter and a nadir in the summer months in both the north and the south of Sweden. Findings were similar with incident MI as the outcome.

Conclusions
The incidence of MI-related death varied markedly by season and latitude in Sweden, with summer months and more southerly latitude associated with lower rates than winter months and more northerly latitude.

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More information

Accepted/In Press date: 11 September 2019
e-pub ahead of print date: 28 November 2019

Identifiers

Local EPrints ID: 439459
URI: http://eprints.soton.ac.uk/id/eprint/439459
ISSN: 1741-3842
PURE UUID: 6c015fbb-743a-4024-bea4-77b31a7b544c
ORCID for Nicholas Harvey: ORCID iD orcid.org/0000-0002-8194-2512

Catalogue record

Date deposited: 23 Apr 2020 16:54
Last modified: 26 Nov 2021 02:48

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Contributors

Author: Nicholas Harvey ORCID iD
Author: Mattias Lorentzen
Author: John A. Kanis
Author: Eugene McCloskey
Author: Helena Johansson

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