Photopatterned PLED arrays for biosensing applications

Vasilopoulou, Maria, Georgiadou, Dimitra G., Palilis, Leonidas C., Botsialas, Athanasios, Petrou, Panagiota S., Kakabakos, Sotirios E. and Argitis, Panagiotis (2009) Photopatterned PLED arrays for biosensing applications. Microelectronic Engineering, 86 (4-6), 1511-1514. (doi:10.1016/j.mee.2009.01.063).

Abstract

A solid-state optical biosensor integrated with a single layer flexible blue Polymer Light Emitting Diode (PLED) as the light source was demonstrated and used for the detection of biomolecules labeled with two different fluorescent dyes. An anti-rabbit IgG antibody labeled with the fluorescent dyes, that was adsorbed on the opposite side of a polyethylene tetraphthalate (PET) flexible substrate, was excited by light emitted from the PLED. Light is then absorbed by the dye-labeled antibody resulting in a red shift of the polymer emission spectrum. Emission originating from the dye is also observed. The emission spectral shift and its efficiency depend primarily on the concentration of the biomolecule solution, the overlap between the emission spectra of the polymer and the absorption spectra of the dye and the PLED emission characteristics. Biomolecules immobilized onto distinct areas of a plastic substrate might then selectively be detected with high sensitivity after reacting with fluorescently labeled counterpart molecules.

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Contributors

Author: Dimitra G. Georgiadou

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