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Gestational diabetes mellitus: An opportunity to improve long term health in mothers and children

Gestational diabetes mellitus: An opportunity to improve long term health in mothers and children
Gestational diabetes mellitus: An opportunity to improve long term health in mothers and children
Gestational diabetes, the most common medical disorder in pregnancy, is defined as glucose intolerance resulting in hyperglycaemia that begins or is first diagnosed in pregnancy. Gestational diabetes is associated with increased pregnancy complications and long-term metabolic risks for the woman and the offspring. However, the current diagnostic and management strategies recommended by national and international guidelines are mainly focused on short-term risks during pregnancy and delivery, except the Carpenter-Coustan criteria, which were based on the risk of future incidence of type 2 diabetes post-gestational diabetes. In this Personal View, first, we summarise the evidence for long-term risk in women with gestational diabetes and their offspring. Second, we suggest that a shift is needed in the thinking about gestational diabetes; moving from the perception of a short-term condition that confers increased risks of large babies to a potentially modifiable long-term condition that contributes to the growing burden of childhood obesity and cardiometabolic disorders in women and the future generation. Third, we propose how the current clinical practice might be improved. Finally, we outline and justify priorities for future research.
2213-8587
793-800
Saravanan, P.
617bf087-f052-46a2-88ce-bc016055d701
Holt, Richard
d54202e1-fcf6-4a17-a320-9f32d7024393
Diabetes in Pregnancy Working Group of the Maternal Medicine Clinical Study Group
Saravanan, P.
617bf087-f052-46a2-88ce-bc016055d701
Holt, Richard
d54202e1-fcf6-4a17-a320-9f32d7024393

Saravanan, P. , Diabetes in Pregnancy Working Group of the Maternal Medicine Clinical Study Group (2020) Gestational diabetes mellitus: An opportunity to improve long term health in mothers and children. The Lancet Diabetes & Endocrinology, 8 (9), 793-800. (doi:10.1016/S2213-8587(20)30161-3).

Record type: Article

Abstract

Gestational diabetes, the most common medical disorder in pregnancy, is defined as glucose intolerance resulting in hyperglycaemia that begins or is first diagnosed in pregnancy. Gestational diabetes is associated with increased pregnancy complications and long-term metabolic risks for the woman and the offspring. However, the current diagnostic and management strategies recommended by national and international guidelines are mainly focused on short-term risks during pregnancy and delivery, except the Carpenter-Coustan criteria, which were based on the risk of future incidence of type 2 diabetes post-gestational diabetes. In this Personal View, first, we summarise the evidence for long-term risk in women with gestational diabetes and their offspring. Second, we suggest that a shift is needed in the thinking about gestational diabetes; moving from the perception of a short-term condition that confers increased risks of large babies to a potentially modifiable long-term condition that contributes to the growing burden of childhood obesity and cardiometabolic disorders in women and the future generation. Third, we propose how the current clinical practice might be improved. Finally, we outline and justify priorities for future research.

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GDM-Personal View-Revision 2-With changes accepted - Accepted Manuscript
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More information

Accepted/In Press date: 30 April 2020
e-pub ahead of print date: 18 August 2020
Published date: 1 September 2020

Identifiers

Local EPrints ID: 440641
URI: http://eprints.soton.ac.uk/id/eprint/440641
ISSN: 2213-8587
PURE UUID: 8a652af9-f672-446c-a88d-45907e8e5b4d
ORCID for Richard Holt: ORCID iD orcid.org/0000-0001-8911-6744

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Date deposited: 12 May 2020 16:47
Last modified: 28 Apr 2022 01:48

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Contributors

Author: P. Saravanan
Author: Richard Holt ORCID iD
Corporate Author: Diabetes in Pregnancy Working Group of the Maternal Medicine Clinical Study Group

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