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Chip-and-dip: capillary-driven flow devices for point-of- care diagnostics

Chip-and-dip: capillary-driven flow devices for point-of- care diagnostics
Chip-and-dip: capillary-driven flow devices for point-of- care diagnostics
This paper showcases a capillary-driven flow microfluidics device easy for detection with pump-free sample loading into microchannels. The device is coated with hydrophilic material and cross-linked with sample-specific reagents. While this platform could be tailored for a wide variety of assays, here we show the design, fabrication and working principle of the device along with a specific application for Beta-lactamase activity and cortisol assay. Ultimately, the device will be used for antimicrobial resistance (AMR) testing in healthcare.
685-686
Hassan, Sammer-Ul
8a5ae3f1-3451-4093-879e-85f40953da8b
Zhang, Xunli
d7cf1181-3276-4da1-9150-e212b333abb1
Hassan, Sammer-Ul
8a5ae3f1-3451-4093-879e-85f40953da8b
Zhang, Xunli
d7cf1181-3276-4da1-9150-e212b333abb1

Hassan, Sammer-Ul and Zhang, Xunli (2019) Chip-and-dip: capillary-driven flow devices for point-of- care diagnostics. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences. pp. 685-686 .

Record type: Conference or Workshop Item (Paper)

Abstract

This paper showcases a capillary-driven flow microfluidics device easy for detection with pump-free sample loading into microchannels. The device is coated with hydrophilic material and cross-linked with sample-specific reagents. While this platform could be tailored for a wide variety of assays, here we show the design, fabrication and working principle of the device along with a specific application for Beta-lactamase activity and cortisol assay. Ultimately, the device will be used for antimicrobial resistance (AMR) testing in healthcare.

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Chip and Dip
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More information

Published date: 23 October 2019

Identifiers

Local EPrints ID: 440662
URI: http://eprints.soton.ac.uk/id/eprint/440662
PURE UUID: afa5105e-14f9-45bc-a140-7c0c6de0fa79
ORCID for Sammer-Ul Hassan: ORCID iD orcid.org/0000-0002-0319-5814
ORCID for Xunli Zhang: ORCID iD orcid.org/0000-0002-4375-1571

Catalogue record

Date deposited: 13 May 2020 16:33
Last modified: 18 Feb 2021 17:20

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