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Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science

Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science
Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science
The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all aspects of society, including mental health and physical health. We explore the psychological, social, and neuroscientific effects of COVID-19 and set out the immediate priorities and longer-term strategies for mental health science research. These priorities were informed by surveys of the public and an expert panel convened by the UK Academy of Medical Sciences and the mental health research charity, MQ: Transforming Mental Health, in the first weeks of the pandemic in the UK in March, 2020. We urge UK research funding agencies to work with researchers, people with lived experience, and others to establish a high level coordination group to ensure that these research priorities are addressed, and to allow new ones to be identified over time. The need to maintain high-quality research standards is imperative. International collaboration and a global perspective will be beneficial. An immediate priority is collecting high-quality data on the mental health effects of the COVID-19 pandemic across the whole population and vulnerable groups, and on brain function, cognition, and mental health of patients with COVID-19. There is an urgent need for research to address how mental health consequences for vulnerable groups can be mitigated under pandemic conditions, and on the impact of repeated media consumption and health messaging around COVID-19. Discovery, evaluation, and refinement of mechanistically driven interventions to address the psychological, social, and neuroscientific aspects of the pandemic are required. Rising to this challenge will require integration across disciplines and sectors, and should be done together with people with lived experience. New funding will be required to meet these priorities, and it can be efficiently leveraged by the UK's world-leading infrastructure. This Position Paper provides a strategy that may be both adapted for, and integrated with, research efforts in other countries.
2215-0366
547-560
Holmes, Emily
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O'Connor, Rory
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Perry, Hugh
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Wessely, Simon
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Arseneault, Louise
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Ballard, Clive
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Hotopf, Matthew
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Bullmore, Edward T.
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Holmes, Emily
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Perry, Hugh
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Wessely, Simon
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Ford, Tamsin
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Worthman, Carol
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Yardley, Lucy
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Cowan, Katherine
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Cope, Claire
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Hotopf, Matthew
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Bullmore, Edward T.
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Holmes, Emily, O'Connor, Rory, Perry, Hugh, Tracey, Irene, Wessely, Simon, Arseneault, Louise, Ballard, Clive, Christensen, Helen, Cohen Silver, Roxane, Everall, Ian, Ford, Tamsin, John, Ann, Kabir, Thomas, King, Kate, Madan, Ira, Michie, Susan, Przybylski, Andrew, Shafran, Roz, Sweeney, Angela, Worthman, Carol, Yardley, Lucy, Cowan, Katherine, Cope, Claire, Hotopf, Matthew and Bullmore, Edward T. (2020) Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science. Lancet Psychiatry, 7 (6), 547-560. (doi:10.1016/S2215-0366(20)30168-1).

Record type: Article

Abstract

The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all aspects of society, including mental health and physical health. We explore the psychological, social, and neuroscientific effects of COVID-19 and set out the immediate priorities and longer-term strategies for mental health science research. These priorities were informed by surveys of the public and an expert panel convened by the UK Academy of Medical Sciences and the mental health research charity, MQ: Transforming Mental Health, in the first weeks of the pandemic in the UK in March, 2020. We urge UK research funding agencies to work with researchers, people with lived experience, and others to establish a high level coordination group to ensure that these research priorities are addressed, and to allow new ones to be identified over time. The need to maintain high-quality research standards is imperative. International collaboration and a global perspective will be beneficial. An immediate priority is collecting high-quality data on the mental health effects of the COVID-19 pandemic across the whole population and vulnerable groups, and on brain function, cognition, and mental health of patients with COVID-19. There is an urgent need for research to address how mental health consequences for vulnerable groups can be mitigated under pandemic conditions, and on the impact of repeated media consumption and health messaging around COVID-19. Discovery, evaluation, and refinement of mechanistically driven interventions to address the psychological, social, and neuroscientific aspects of the pandemic are required. Rising to this challenge will require integration across disciplines and sectors, and should be done together with people with lived experience. New funding will be required to meet these priorities, and it can be efficiently leveraged by the UK's world-leading infrastructure. This Position Paper provides a strategy that may be both adapted for, and integrated with, research efforts in other countries.

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e-pub ahead of print date: 15 April 2020
Published date: June 2020
Additional Information: Funding Information: CB reports grants and personal fees from Acadia and Lundbeck; personal fees from Roche, Otsuka, Biogen, Eli Lilly, Novo Nordisk, AARP, and Exciva; and grants from Synexus, outside the submitted work. EAH reports serving on the board of trustees of the charity MQ: Transforming Mental Health and as chair of the research committee, but receives no remuneration for these roles. EAH receives royalties from books and occasional fees for workshops and invited addresses; receives occasional consultancy fees from the Swedish agency for health technology assessment and assessment of social services; and reports grants from The OAK Foundation, the Lupina Foundation, and the Swedish Research Council. RCO'C is a member of the National Institute of Health and Care Excellence's guideline development group for the management of self-harm; is co-chair of the Academic Advisory Group to the Scottish Government's National Suicide Prevention Leadership Group; receives royalties from books, and occasional fees for workshops and invited addresses; and reports grants from Medical Research Foundation, the Mindstep Foundation, Chief Scientist Office, Medical Research Council, NHS Health Scotland, Scottish Government, and National Institute for Health Research (NIHR). KK has received meeting attendance payments from the Department of Health and Social Care, NHS England and NHS Improvement, and the Royal College of Psychiatry (RCPsych) over the last year for service user representative work, and payment for a training session she facilitated for RCPsych; and received a pass and accommodation for the RCPsych annual conference in 2019. AKP reports financial support from UK taxpayers, the UK's Economic and Social Research Council, the British Academy, the Diana Award, the John Fell Fund, the Leverhulme Trust, Barnardo's UK, and the Huo Family Foundation in the past five years. As part of science communication and policy outreach activities; and served in an unpaid advisory capacity to the Organization for Economic Co-operation and Development, Facebook, Google, and the ParentZone. IT is a Trustee of MQ: Transforming Mental Health and is on the Council for the Medical Research Council of the UK. MH reports grants from Innovative Medicines Intiative, outside the submitted work. MH and SW are funded by the NIHR Biomedical Research Centre at the Maudsley and a NIHR Senior Investigator Award. NIHR were not involved in any aspect of the publication and had no role in the decision to submit. RCS received funding from the US National Science Foundation, grant SES-2026337. CC reported that Academy of Medical Sciences staff, including herself, and activity costs for this work were partly supported by a core grant the Academy of Medical Sciences receives annually from the Government Department for Business, Energy & Industrial Strategy for policy, communications and public engagement; and reports that her husband is an employee of Otsuka Pharmaceutical Europe and is a trustee of The McPin Foundation. KC was funded by MQ: Transforming Mental Health to carry out the qualitative data analysis of the stakeholder survey. LA is the Mental Health Leadership Fellow for the Economic and Social Research Council. EB is a NIHR Senior Investigator. This Position Paper represents independent research part-funded by the NIHR Biomedical Research Centre at Cambridge University Hospital NHS Trust and the University of Cambridge and South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health and Social Care. RS reports that all research at Great Ormond Street Hospital NHS Foundation Trust and UCL Great Ormond Street Institute of Child Health is made possible by the NIHR Great Ormond Street Hospital Biomedical Research Centre. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. LY is an NIHR Senior Investigator and her research programme is partly supported by NIHR Applied Research Collaboration-West, NIHR Health Protection Research Unit for Behavioural Science and Evaluation, and the NIHR Southampton Biomedical Research Centre. The funding for TK's salary came solely from The McPin Foundation. All other authors declare no competing interests. Funding Information: The stakeholder survey was funded by MQ: Transforming Mental Health. Activity costs for this work, including the Ipsos MORI survey, were partly supported by a core grant the Academy of Medical Sciences receives annually from the Government Department for Business, Energy & Industrial Strategy for policy, communications and public engagement. The views expressed are the views of the authors alone and do not necessarily represent the views of their organisations or funding sources. Publisher Copyright: © 2020 Elsevier Ltd

Identifiers

Local EPrints ID: 441110
URI: http://eprints.soton.ac.uk/id/eprint/441110
ISSN: 2215-0366
PURE UUID: c7489813-c2c4-41e3-bb9e-5b0931a8eb99
ORCID for Lucy Yardley: ORCID iD orcid.org/0000-0002-3853-883X

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Date deposited: 02 Jun 2020 16:30
Last modified: 17 Mar 2024 05:37

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Contributors

Author: Emily Holmes
Author: Rory O'Connor
Author: Hugh Perry
Author: Irene Tracey
Author: Simon Wessely
Author: Louise Arseneault
Author: Clive Ballard
Author: Helen Christensen
Author: Roxane Cohen Silver
Author: Ian Everall
Author: Tamsin Ford
Author: Ann John
Author: Thomas Kabir
Author: Kate King
Author: Ira Madan
Author: Susan Michie
Author: Andrew Przybylski
Author: Roz Shafran
Author: Angela Sweeney
Author: Carol Worthman
Author: Lucy Yardley ORCID iD
Author: Katherine Cowan
Author: Claire Cope
Author: Matthew Hotopf
Author: Edward T. Bullmore

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