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Use of a pulsed fibre laser as an excitation source for photoacoustic tomography

Use of a pulsed fibre laser as an excitation source for photoacoustic tomography
Use of a pulsed fibre laser as an excitation source for photoacoustic tomography
The use of a pulsed fibre laser as an excitation source for photoacoustic tomography has been investigated. Fibre lasers have the advantage of being compact, robust and efficient compared to traditional excitation sources used for photoacoustic tomography (e.g. Q-switched Nd:YAG pumped OPO or dye systems). Their high pulse repetition frequencies and adjustable pulse duration, shape and duty cycle also enables a wide range of time and frequency domain excitation methods to be investigated. A 1060nm, 20W fibre laser was used to generate acoustic waves in a tissue mimicking phantom composed of blood filled tubes immersed in a 1% solution of intralipid (mu's=1mm-1) . The laser was then combined with a Fabry Perot photoacoustic imaging system to obtain 3D images of a tissue mimicking phantom and an in vivo image of the vasculature of the palm of a volunteer. This study has demonstrated that pulsed fibre lasers have potential application as an excitation source for photoacoustic imaging of superficial blood vessels.SPIE 7899 Progress in Biomedical Optics and ImagingSan Francisco, CA23-25 Jan
SPIE
Allen, T.J.
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Alam, S.
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Zhang, E.Z.
d98bcd67-bc62-4315-8df3-de57a6fa975c
Laufer, J.G.
c849684d-82b1-4216-a243-1c41cf0abacc
Richardson, D.J.
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Beard, P.C.
cd0d1cb3-0cbf-4669-b744-d0750a6d7ef2
Allen, T.J.
b133860c-b02d-457b-bf57-831dd8584136
Alam, S.
2b6bdbe5-ddcc-4a88-9057-299360b93435
Zhang, E.Z.
d98bcd67-bc62-4315-8df3-de57a6fa975c
Laufer, J.G.
c849684d-82b1-4216-a243-1c41cf0abacc
Richardson, D.J.
ebfe1ff9-d0c2-4e52-b7ae-c1b13bccdef3
Beard, P.C.
cd0d1cb3-0cbf-4669-b744-d0750a6d7ef2

Allen, T.J., Alam, S., Zhang, E.Z., Laufer, J.G., Richardson, D.J. and Beard, P.C. (2011) Use of a pulsed fibre laser as an excitation source for photoacoustic tomography. In Photons Plus Ultrasound: Imaging and Sensing 2011. vol. 7899, SPIE.. (doi:10.1117/12.875291).

Record type: Conference or Workshop Item (Paper)

Abstract

The use of a pulsed fibre laser as an excitation source for photoacoustic tomography has been investigated. Fibre lasers have the advantage of being compact, robust and efficient compared to traditional excitation sources used for photoacoustic tomography (e.g. Q-switched Nd:YAG pumped OPO or dye systems). Their high pulse repetition frequencies and adjustable pulse duration, shape and duty cycle also enables a wide range of time and frequency domain excitation methods to be investigated. A 1060nm, 20W fibre laser was used to generate acoustic waves in a tissue mimicking phantom composed of blood filled tubes immersed in a 1% solution of intralipid (mu's=1mm-1) . The laser was then combined with a Fabry Perot photoacoustic imaging system to obtain 3D images of a tissue mimicking phantom and an in vivo image of the vasculature of the palm of a volunteer. This study has demonstrated that pulsed fibre lasers have potential application as an excitation source for photoacoustic imaging of superficial blood vessels.SPIE 7899 Progress in Biomedical Optics and ImagingSan Francisco, CA23-25 Jan

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More information

Published date: 28 February 2011
Venue - Dates: SPIE 7899: Progress in Biomedical Optics and Imaging, 2011-01-23 - 2011-01-25

Identifiers

Local EPrints ID: 441124
URI: http://eprints.soton.ac.uk/id/eprint/441124
PURE UUID: 8760a752-b951-40ba-a3e9-cb5f1a0c1733
ORCID for D.J. Richardson: ORCID iD orcid.org/0000-0002-7751-1058

Catalogue record

Date deposited: 02 Jun 2020 16:30
Last modified: 03 Jun 2020 00:25

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