READ ME File For 'Raw Data for Bactericidal effect of 5-mercapto-2-nitrobenzoic acid coated silver nanoclusters against multidrug-resistant Neisseria gonorrhoeae'

Dataset DOI: https://doi.org/10.5258/SOTON/D1313

ReadMe Author: Maria Isabel Lucio, Maria-Eleni Kyriazi, Myron Christodoulides and Antonios G. Kanaras, University of Southampton


This dataset supports the publication:
AUTHORS:Maria-Isabel Lucio, Maria-Eleni Kyriazi, Vicky Humbert, Myron Christodoulides, Antonios G. Kanaras
TITLE:"Bactericidal effect of 5-mercapto-2-nitrobenzoic acid coated silver nanoclusters against multidrug-resistant Neisseria gonorrhoeae"
JOURNAL: ACS Applied Materials & Interfaces


Contents


In particular the dataset contains the data recorded to generate the following figures included in the publication. 

The figures are as follows:


Fig. 1b: Representative UV-Vis spectrum of AgNCs stabilized by MNBA 

Fig. 2:  Killing of N. gonorrhoeae strain P9-17 with increasing concentrations of MNBA-AgNCs, ceftriaxone and AgNO3 at different incubation times

Fig. 3a: Minimum time required to kill N. gonorrhoeae strain P9-17 

Fig. 3b: Killing effect of MNBA-AgNCs (0.467 µM) on increasing concentrations of N. gonorrhoeae 

Fig. 4: Assessment of gonococcal viability in the presence of MNBA-AgNCs 

Fig. 5a: Effect of MNBA-AgNCs during short-term infection

Fig. 5b: Effect of 24h treatment with various doses of MNBA-AgNCs

Fig. S2: Viability of Human Chang conjunctival epithelial cells 

Fig. S3: Activity of MNBA-AgNCs on planktonic bacteria

Fig S4: Killing of N. gonorrhoeae strain P9-17 with MNBA-AgNCs

Table 1: Concentrations of MNBA-AgNCs that kill 50% and 100% of N. gonorrhoeae isolates compared with MIC values for ceftriaxone and azithromycin

Date of data collection: 2017-2018-2019

Geographic location of data collection: University of Southampton, U.K.

Related projects: BBSRC (BB/N021150/1)

Dataset available under a CC BY 4.0 licence


Publisher: University of Southampton, U.K.


Date file created: April 2020