Cost-effectiveness of low-level heat wrap therapy for low back pain
Cost-effectiveness of low-level heat wrap therapy for low back pain
OBJECTIVES: To evaluate the cost-effectiveness and budget impact of a new heat wrap therapy for low back pain compared to paracetamol and ibuprofen from the perspective of the UK National Health Service (NHS).
METHODS: We evaluated cost-effectiveness using data from a phase III trial comparing the three therapies in 371 patients aged 18 to 55 years presenting with acute uncomplicated low back pain. The primary effectiveness measure used was successful treatment, defined as both clinically meaningful pain relief and clinically meaningful reduction in disability. We conducted a simple evaluation using NHS prescription costs and a modeled extrapolation including the costs of further treatment and consultations for patients treated unsuccessfully or with adverse events. Uncertainty was addressed using nonparametric bootstrapping and sensitivity analyses.
RESULTS: Successful treatment was reported by 57% of patients treated with heat wrap therapy, 26% treated with paracetamol and 18% treated with ibuprofen (P < 0.05 for heat wrap vs. both other groups). NHS prescription cost per patient was estimated to be 1.35 pounds Sterling for heat wrap therapy, 0.26 pounds Sterling for paracetamol, and 0.28 pounds Sterling for ibuprofen and cost per successful treatment was 3.52 pounds Sterling for heat wrap therapy compared to paracetamol, and 2.72 pounds Sterling compared to ibuprofen. In the modeled extrapolation, NHS cost per patient was 27.77 pounds Sterling for heat wrap therapy, 34.20 pounds Sterling for paracetamol, and 36.04 pounds Sterling for ibuprofen. Sensitivity analyses indicated that the findings were robust to plausible changes in data and assumptions.
CONCLUSIONS: Economic evaluation of this study suggests that the NHS cost of introducing heat wrap therapy in place of oral analgesics would be modest and heat wrap therapy might potentially reduce the total cost of managing episodes of lower back pain.
Acetaminophen/therapeutic use, Adolescent, Adult, Analgesics, Non-Narcotic/therapeutic use, Budgets, Confidence Intervals, Cost-Benefit Analysis, Follow-Up Studies, Humans, Hyperthermia, Induced/economics, Ibuprofen/therapeutic use, Low Back Pain/drug therapy, Middle Aged, Time Factors, United Kingdom
413-422
Lloyd, Adam
a7274aaf-5c15-4485-bb9a-52806c919647
Scott, David A
19b5fd34-9974-4ae4-8be0-27a693639e20
Akehurst, Ron L
9d6694f9-7a4d-471f-aae2-09e881b26214
Lurie-Luke, Elena
bc47da35-78d2-4945-9dd0-b3d5a9c78231
Jessen, George
62ea7cd2-ff0b-4e63-9205-efe05e475333
29 September 2004
Lloyd, Adam
a7274aaf-5c15-4485-bb9a-52806c919647
Scott, David A
19b5fd34-9974-4ae4-8be0-27a693639e20
Akehurst, Ron L
9d6694f9-7a4d-471f-aae2-09e881b26214
Lurie-Luke, Elena
bc47da35-78d2-4945-9dd0-b3d5a9c78231
Jessen, George
62ea7cd2-ff0b-4e63-9205-efe05e475333
Lloyd, Adam, Scott, David A, Akehurst, Ron L, Lurie-Luke, Elena and Jessen, George
(2004)
Cost-effectiveness of low-level heat wrap therapy for low back pain.
Value in Health, 7 (4), .
(doi:10.1111/j.1524-4733.2004.74004.x).
Abstract
OBJECTIVES: To evaluate the cost-effectiveness and budget impact of a new heat wrap therapy for low back pain compared to paracetamol and ibuprofen from the perspective of the UK National Health Service (NHS).
METHODS: We evaluated cost-effectiveness using data from a phase III trial comparing the three therapies in 371 patients aged 18 to 55 years presenting with acute uncomplicated low back pain. The primary effectiveness measure used was successful treatment, defined as both clinically meaningful pain relief and clinically meaningful reduction in disability. We conducted a simple evaluation using NHS prescription costs and a modeled extrapolation including the costs of further treatment and consultations for patients treated unsuccessfully or with adverse events. Uncertainty was addressed using nonparametric bootstrapping and sensitivity analyses.
RESULTS: Successful treatment was reported by 57% of patients treated with heat wrap therapy, 26% treated with paracetamol and 18% treated with ibuprofen (P < 0.05 for heat wrap vs. both other groups). NHS prescription cost per patient was estimated to be 1.35 pounds Sterling for heat wrap therapy, 0.26 pounds Sterling for paracetamol, and 0.28 pounds Sterling for ibuprofen and cost per successful treatment was 3.52 pounds Sterling for heat wrap therapy compared to paracetamol, and 2.72 pounds Sterling compared to ibuprofen. In the modeled extrapolation, NHS cost per patient was 27.77 pounds Sterling for heat wrap therapy, 34.20 pounds Sterling for paracetamol, and 36.04 pounds Sterling for ibuprofen. Sensitivity analyses indicated that the findings were robust to plausible changes in data and assumptions.
CONCLUSIONS: Economic evaluation of this study suggests that the NHS cost of introducing heat wrap therapy in place of oral analgesics would be modest and heat wrap therapy might potentially reduce the total cost of managing episodes of lower back pain.
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More information
Published date: 29 September 2004
Keywords:
Acetaminophen/therapeutic use, Adolescent, Adult, Analgesics, Non-Narcotic/therapeutic use, Budgets, Confidence Intervals, Cost-Benefit Analysis, Follow-Up Studies, Humans, Hyperthermia, Induced/economics, Ibuprofen/therapeutic use, Low Back Pain/drug therapy, Middle Aged, Time Factors, United Kingdom
Identifiers
Local EPrints ID: 441366
URI: http://eprints.soton.ac.uk/id/eprint/441366
ISSN: 1098-3015
PURE UUID: 050b9487-748d-47fe-a792-eb7617825554
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Date deposited: 10 Jun 2020 16:31
Last modified: 17 Mar 2024 04:02
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Contributors
Author:
Adam Lloyd
Author:
David A Scott
Author:
Ron L Akehurst
Author:
Elena Lurie-Luke
Author:
George Jessen
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