2B or not 2B, that is the question: further investigations into the use of pencil as a matrix for matrix-assisted laser desorption/ionisation


Langley, G.J., Herniman, J.M. and Townell, M.S. (2007) 2B or not 2B, that is the question: further investigations into the use of pencil as a matrix for matrix-assisted laser desorption/ionisation Rapid Communications in Mass Spectrometry, 21, (2), pp. 180-190. (doi:10.1002/rcm.2827).

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Description/Abstract

The effective use of pencil as a matrix for matrix-assisted laser desorption/ionisation (MALDI) for the study of actinides has previously been demonstrated (Black et al., Rapid Commun. Mass Spectrom. 2006; 20: 1053). Here, the scope of the types of molecules amenable to analysis by this method has been extended, establishing that 90% of a library containing 50 diverse small molecules can be successfully analysed by this technique. Further, the role played by the bulk materials present in the different pencil leads has been investigated and a simple one-step deposition of matrix and calibration materials has been achieved through the fabrication of different calibration pencils (Cali-Pens)

Item Type: Article
Digital Object Identifier (DOI): doi:10.1002/rcm.2827
ISSNs: 0951-4198 (print)
Keywords: Mass spectrometry, MALDI matrix, pencil matrix, MALDI
Subjects:
ePrint ID: 44150
Date :
Date Event
20 September 2006Submitted
January 2007Published
Date Deposited: 16 Feb 2007
Last Modified: 16 Apr 2017 18:45
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/44150

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