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The effect of human mobility and control measures on the COVID-19 epidemic in China

The effect of human mobility and control measures on the COVID-19 epidemic in China
The effect of human mobility and control measures on the COVID-19 epidemic in China

The ongoing COVID-19 outbreak has expanded rapidly throughout China. Major behavioral, clinical, and state interventions are underway currently to mitigate the epidemic and prevent the persistence of the virus in human populations in China and worldwide. It remains unclear how these unprecedented interventions, including travel restrictions, have affected COVID-19 spread in China. We use real-time mobility data from Wuhan and detailed case data including travel history to elucidate the role of case importation on transmission in cities across China and ascertain the impact of control measures. Early on, the spatial distribution of COVID-19 cases in China was well explained by human mobility data. Following the implementation of control measures, this correlation dropped and growth rates became negative in most locations, although shifts in the demographics of reported cases are still indicative of local chains of transmission outside Wuhan. This study shows that the drastic control measures implemented in China have substantially mitigated the spread of COVID-19.

0036-8075
493-497
Kraemer, Moritz U.G.
5d2b1994-4d71-4eb8-93dd-d948ba164fa2
Yang, Chia-Hung
b6ba0fac-86a8-4240-97b1-0d47098c2292
Gutierrez, Bernardo
0be96646-ada0-4c57-8a56-5118b2b3ef24
Wu, Chieh-Hsi
ace630c6-2095-4ade-b657-241692f6b4d3
Klein, Brennan
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Pigott, David M.
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du Plessis, Louis
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Faria, Nuno R.
cc78a30a-2b32-4b9b-9d46-5c7bd842da37
Li, Ruoran
71a3b045-9dc7-4c5c-bab1-ab5428fba524
Hanage, William P.
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Kraemer, Moritz U.G.
5d2b1994-4d71-4eb8-93dd-d948ba164fa2
Yang, Chia-Hung
b6ba0fac-86a8-4240-97b1-0d47098c2292
Gutierrez, Bernardo
0be96646-ada0-4c57-8a56-5118b2b3ef24
Wu, Chieh-Hsi
ace630c6-2095-4ade-b657-241692f6b4d3
Klein, Brennan
e8803089-2934-45df-b5d0-9450b54a2b74
Pigott, David M.
f2e004f2-dc51-427b-a460-8d0ad9895514
du Plessis, Louis
b73c550f-9e6a-44af-b09a-c863c45efb8e
Faria, Nuno R.
cc78a30a-2b32-4b9b-9d46-5c7bd842da37
Li, Ruoran
71a3b045-9dc7-4c5c-bab1-ab5428fba524
Hanage, William P.
23ab4323-a1d4-4cfb-943b-cd51a97bee77

Kraemer, Moritz U.G., Yang, Chia-Hung, Gutierrez, Bernardo, Wu, Chieh-Hsi, Klein, Brennan, Pigott, David M., du Plessis, Louis, Faria, Nuno R., Li, Ruoran and Hanage, William P. (2020) The effect of human mobility and control measures on the COVID-19 epidemic in China. Science, 368 (6490), 493-497. (doi:10.1101/2020.03.02.20026708).

Record type: Article

Abstract

The ongoing COVID-19 outbreak has expanded rapidly throughout China. Major behavioral, clinical, and state interventions are underway currently to mitigate the epidemic and prevent the persistence of the virus in human populations in China and worldwide. It remains unclear how these unprecedented interventions, including travel restrictions, have affected COVID-19 spread in China. We use real-time mobility data from Wuhan and detailed case data including travel history to elucidate the role of case importation on transmission in cities across China and ascertain the impact of control measures. Early on, the spatial distribution of COVID-19 cases in China was well explained by human mobility data. Following the implementation of control measures, this correlation dropped and growth rates became negative in most locations, although shifts in the demographics of reported cases are still indicative of local chains of transmission outside Wuhan. This study shows that the drastic control measures implemented in China have substantially mitigated the spread of COVID-19.

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More information

Accepted/In Press date: 23 March 2020
e-pub ahead of print date: 25 March 2020
Published date: 1 May 2020
Additional Information: Funding Information: H.T., O.G.P., and M.U.G.K. acknowledge support from the Oxford Martin School. M.U.G.K. is supported by a Branco Weiss Fellowship. B.G. is supported by a Universities of Academic Excellence Scholarship Program of the Secretariat for Higher Education, Science, Technology, and Innovation of the Republic of Ecuador (grant no. ARSEQ-BEC-003163-2017). N.R.F. is supported by a Sir Henry Dale Fellowship. W.P.H. is supported by the National Institute of General Medical Sciences (grant no. U54GM088558). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Publisher Copyright: Copyright © 2020 The Authors,

Identifiers

Local EPrints ID: 441514
URI: http://eprints.soton.ac.uk/id/eprint/441514
ISSN: 0036-8075
PURE UUID: 28996b4e-7f3b-4df6-a028-982935c3baec
ORCID for Chieh-Hsi Wu: ORCID iD orcid.org/0000-0001-9386-725X

Catalogue record

Date deposited: 16 Jun 2020 16:34
Last modified: 17 Mar 2024 04:00

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Contributors

Author: Moritz U.G. Kraemer
Author: Chia-Hung Yang
Author: Bernardo Gutierrez
Author: Chieh-Hsi Wu ORCID iD
Author: Brennan Klein
Author: David M. Pigott
Author: Louis du Plessis
Author: Nuno R. Faria
Author: Ruoran Li
Author: William P. Hanage

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