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A cost-effectiveness analysis of long-term intermittent catheterisation with hydrophilic and uncoated catheters

A cost-effectiveness analysis of long-term intermittent catheterisation with hydrophilic and uncoated catheters
A cost-effectiveness analysis of long-term intermittent catheterisation with hydrophilic and uncoated catheters

STUDY DESIGN: Cost-effectiveness analysisObjective:To establish a model to investigate the cost effectiveness for people with spinal cord injury (SCI), from a lifetime perspective, for the usage of two different single-use catheter designs: hydrophilic-coated (HC) and uncoated (UC). The model includes the long-term sequelae of impaired renal function and urinary tract infection (UTI).

SETTING: Analysis based on a UK perspective.

METHODS: A probabilistic Markov decision model was constructed, to compare lifetime costs and quality-adjusted life years, taking renal and UTI health states into consideration, as well as other catheter-related events. UTI event rates for the primary data set were based on data from hospital settings to ensure controlled and accurate reporting. A sensitivity analysis was applied to evaluate best- and worst-case scenarios.

RESULTS: The model predicts that a 36-year-old SCI patient with chronic urinary retention will live an additional 1.4 years if using HC catheters compared with UC catheters, at an incremental cost of £2100. Moreover, the lifetime number of UTI events will be reduced by 16%. All best- and worst-case estimates were within the UK threshold of being cost effective.

CONCLUSION: The use of HC catheters for intermittent catheterisation in SCI patients is highly cost effective. The outcome is consistent irrespective of whether UTI data are collected in hospital or community settings.

Adult, Cohort Studies, Cost-Benefit Analysis, Datasets as Topic/statistics & numerical data, Equipment Design/economics, Female, Humans, Male, Markov Chains, Middle Aged, Quality of Life, Quality-Adjusted Life Years, Spinal Cord Injuries/complications, United Kingdom, Urinary Catheterization/adverse effects, Urinary Tract Infections/economics, Young Adult
1362-4393
73-77
Clark, J.F.
60fef0a5-d87e-4961-aebd-845df7ca09eb
Mealing, S.J.
545bb166-644d-4f59-a1ab-3200a33aedbe
Scott, D.A.
19b5fd34-9974-4ae4-8be0-27a693639e20
Vogel, L.C.
8c4c749f-af11-45e2-955d-9b3e91a56aa2
Krassioukov, A.
b1838aab-b997-449a-9aba-d729d704a9f6
Spinelli, M.
738d2a73-85a9-4981-b0b5-67373a95d353
Bagi, P.
4e2ca827-9bbc-41cc-b49b-cbb94879fdbe
Wyndaele, J.-J.
9ed31487-0f8b-4a55-8c05-3baa6cc7b94d
Clark, J.F.
60fef0a5-d87e-4961-aebd-845df7ca09eb
Mealing, S.J.
545bb166-644d-4f59-a1ab-3200a33aedbe
Scott, D.A.
19b5fd34-9974-4ae4-8be0-27a693639e20
Vogel, L.C.
8c4c749f-af11-45e2-955d-9b3e91a56aa2
Krassioukov, A.
b1838aab-b997-449a-9aba-d729d704a9f6
Spinelli, M.
738d2a73-85a9-4981-b0b5-67373a95d353
Bagi, P.
4e2ca827-9bbc-41cc-b49b-cbb94879fdbe
Wyndaele, J.-J.
9ed31487-0f8b-4a55-8c05-3baa6cc7b94d

Clark, J.F., Mealing, S.J., Scott, D.A., Vogel, L.C., Krassioukov, A., Spinelli, M., Bagi, P. and Wyndaele, J.-J. (2016) A cost-effectiveness analysis of long-term intermittent catheterisation with hydrophilic and uncoated catheters. Spinal Cord, 54 (1), 73-77. (doi:10.1038/sc.2015.117).

Record type: Article

Abstract

STUDY DESIGN: Cost-effectiveness analysisObjective:To establish a model to investigate the cost effectiveness for people with spinal cord injury (SCI), from a lifetime perspective, for the usage of two different single-use catheter designs: hydrophilic-coated (HC) and uncoated (UC). The model includes the long-term sequelae of impaired renal function and urinary tract infection (UTI).

SETTING: Analysis based on a UK perspective.

METHODS: A probabilistic Markov decision model was constructed, to compare lifetime costs and quality-adjusted life years, taking renal and UTI health states into consideration, as well as other catheter-related events. UTI event rates for the primary data set were based on data from hospital settings to ensure controlled and accurate reporting. A sensitivity analysis was applied to evaluate best- and worst-case scenarios.

RESULTS: The model predicts that a 36-year-old SCI patient with chronic urinary retention will live an additional 1.4 years if using HC catheters compared with UC catheters, at an incremental cost of £2100. Moreover, the lifetime number of UTI events will be reduced by 16%. All best- and worst-case estimates were within the UK threshold of being cost effective.

CONCLUSION: The use of HC catheters for intermittent catheterisation in SCI patients is highly cost effective. The outcome is consistent irrespective of whether UTI data are collected in hospital or community settings.

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More information

Accepted/In Press date: 9 June 2015
e-pub ahead of print date: 21 July 2015
Published date: January 2016
Keywords: Adult, Cohort Studies, Cost-Benefit Analysis, Datasets as Topic/statistics & numerical data, Equipment Design/economics, Female, Humans, Male, Markov Chains, Middle Aged, Quality of Life, Quality-Adjusted Life Years, Spinal Cord Injuries/complications, United Kingdom, Urinary Catheterization/adverse effects, Urinary Tract Infections/economics, Young Adult

Identifiers

Local EPrints ID: 441556
URI: http://eprints.soton.ac.uk/id/eprint/441556
ISSN: 1362-4393
PURE UUID: 081a675b-69c2-4a7d-af29-fcac614783a0
ORCID for D.A. Scott: ORCID iD orcid.org/0000-0001-6475-8046

Catalogue record

Date deposited: 17 Jun 2020 16:36
Last modified: 17 Mar 2024 04:02

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Contributors

Author: J.F. Clark
Author: S.J. Mealing
Author: D.A. Scott ORCID iD
Author: L.C. Vogel
Author: A. Krassioukov
Author: M. Spinelli
Author: P. Bagi
Author: J.-J. Wyndaele

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