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Extra-pulmonary complications of COVID-19: a multi-system disease?

Extra-pulmonary complications of COVID-19: a multi-system disease?
Extra-pulmonary complications of COVID-19: a multi-system disease?

The outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently declared a pandemic by the World Health Organization. In addition to its acute respiratory manifestations, SARS-CoV-2 may also adversely affect other organ systems. To date, however, there is a very limited understanding of the extent and management of COVID-19-related conditions outside of the pulmonary system. This narrative review provides an overview of the current literature about the extrapulmonary manifestations of COVID-19 that may affect the urinary, cardiovascular, gastrointestinal, hematological, hematopoietic, neurological, or reproductive systems. This review also describes the current understanding of the extrapulmonary complications caused by COVID-19 to improve the management and prognosis of patients with COVID-19.

COVID-19, SARS-CoV-2, extrapulmonary manifestations, management
0146-6615
323-335
Zheng, Kenneth I.
4bd07b5b-1281-48ed-8451-d53d21715ae6
Feng, Gong
4f336320-49c8-4ab1-ac95-26905c8fddbb
Liu, Wen-Yue
9b93a204-2543-4936-9255-2936cfa92f74
Targher, Giovanni
043e0811-b389-4922-974e-22e650212c5f
Byrne, Christopher
1370b997-cead-4229-83a7-53301ed2a43c
Zheng, Ming-Hua
405bcc0a-bdd8-4b22-af83-062cfe350484
Zheng, Kenneth I.
4bd07b5b-1281-48ed-8451-d53d21715ae6
Feng, Gong
4f336320-49c8-4ab1-ac95-26905c8fddbb
Liu, Wen-Yue
9b93a204-2543-4936-9255-2936cfa92f74
Targher, Giovanni
043e0811-b389-4922-974e-22e650212c5f
Byrne, Christopher
1370b997-cead-4229-83a7-53301ed2a43c
Zheng, Ming-Hua
405bcc0a-bdd8-4b22-af83-062cfe350484

Zheng, Kenneth I., Feng, Gong, Liu, Wen-Yue, Targher, Giovanni, Byrne, Christopher and Zheng, Ming-Hua (2020) Extra-pulmonary complications of COVID-19: a multi-system disease? Journal of Medical Virology, 93 (1), 323-335. (doi:10.1002/jmv.26294).

Record type: Review

Abstract

The outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently declared a pandemic by the World Health Organization. In addition to its acute respiratory manifestations, SARS-CoV-2 may also adversely affect other organ systems. To date, however, there is a very limited understanding of the extent and management of COVID-19-related conditions outside of the pulmonary system. This narrative review provides an overview of the current literature about the extrapulmonary manifestations of COVID-19 that may affect the urinary, cardiovascular, gastrointestinal, hematological, hematopoietic, neurological, or reproductive systems. This review also describes the current understanding of the extrapulmonary complications caused by COVID-19 to improve the management and prognosis of patients with COVID-19.

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More information

Accepted/In Press date: 7 July 2020
e-pub ahead of print date: 10 July 2020
Published date: 10 July 2020
Additional Information: Running title: Extra-pulmonary complications and COVID-19
Keywords: COVID-19, SARS-CoV-2, extrapulmonary manifestations, management

Identifiers

Local EPrints ID: 442169
URI: http://eprints.soton.ac.uk/id/eprint/442169
ISSN: 0146-6615
PURE UUID: 5923b8b9-0655-418b-8803-415bf49d1f0d
ORCID for Christopher Byrne: ORCID iD orcid.org/0000-0001-6322-7753

Catalogue record

Date deposited: 08 Jul 2020 16:30
Last modified: 17 Mar 2024 05:44

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Contributors

Author: Kenneth I. Zheng
Author: Gong Feng
Author: Wen-Yue Liu
Author: Giovanni Targher
Author: Ming-Hua Zheng

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