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The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO

The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO
The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO
Enhanced half‐life factor VIII and IX products are being introduced into routine clinical practice. Published data report on clinical trials and there are limited data available on how to use these products in routine clinical practice. Many patients, for example, those with a past history of an inhibitor, have been excluded from clinical trials and there are limited data published on children. This guidance document is a consensus statement from the UK Haemophilia Centres Doctors' Organisation and aims to give pragmatic advice on the use of these products in routine practice.
1351-8216
487-498
Collins, P.
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Chalmers, E.
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Chowdary, P.
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Keeling, D.
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Mathias, M.
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O'donnell, J.
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Pasi, K. J.
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Rangarajan, S.
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Thomas, A.
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Collins, P.
f9aca28f-9bc3-45b8-aa5b-b36c974c94c6
Chalmers, E.
af5bb068-8312-47a5-8842-48b82e3a9787
Chowdary, P.
486dd610-f471-49ab-b999-c2145bdd62c3
Keeling, D.
113e2f8d-9051-4312-9d7c-0f147e237d2b
Mathias, M.
1fd987a0-a6b4-45d4-b992-4282e6b51555
O'donnell, J.
10102a79-e385-4506-9631-f543ba7dd41a
Pasi, K. J.
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Rangarajan, S.
9a5e4c7e-55ba-4a3a-b5f6-f1e269d927c3
Thomas, A.
56ca65f4-0761-442d-9266-d87443ef40fe

Collins, P., Chalmers, E., Chowdary, P., Keeling, D., Mathias, M., O'donnell, J., Pasi, K. J., Rangarajan, S. and Thomas, A. (2016) The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO. Haemophilia, 22 (4), 487-498. (doi:10.1111/hae.13013).

Record type: Article

Abstract

Enhanced half‐life factor VIII and IX products are being introduced into routine clinical practice. Published data report on clinical trials and there are limited data available on how to use these products in routine clinical practice. Many patients, for example, those with a past history of an inhibitor, have been excluded from clinical trials and there are limited data published on children. This guidance document is a consensus statement from the UK Haemophilia Centres Doctors' Organisation and aims to give pragmatic advice on the use of these products in routine practice.

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More information

Accepted/In Press date: 12 May 2016
e-pub ahead of print date: 16 June 2016
Published date: 1 July 2016

Identifiers

Local EPrints ID: 442890
URI: http://eprints.soton.ac.uk/id/eprint/442890
ISSN: 1351-8216
PURE UUID: 324928ad-d46c-4df2-ae5f-11b125223abc
ORCID for S. Rangarajan: ORCID iD orcid.org/0000-0001-7367-133X

Catalogue record

Date deposited: 30 Jul 2020 16:31
Last modified: 01 Jul 2022 02:05

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Contributors

Author: P. Collins
Author: E. Chalmers
Author: P. Chowdary
Author: D. Keeling
Author: M. Mathias
Author: J. O'donnell
Author: K. J. Pasi
Author: S. Rangarajan ORCID iD
Author: A. Thomas

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