Strategies for living well with hormone-responsive advanced prostate cancer—a qualitative exploration
Strategies for living well with hormone-responsive advanced prostate cancer—a qualitative exploration
Purpose
Due to recent treatment advances, men are increasingly living longer with advanced prostate cancer (PCa). This study sought to understand men’s experiences of living with and adjusting to advanced hormone-responsive PCa and how this influenced their quality of life (QoL), in order to highlight how support could be optimized.
Methods
Participants were recruited through a UK wide survey—the ‘Life After Prostate Cancer Diagnosis’ study. In-depth telephone interviews were conducted with 24 men (aged 46–77 years) with advanced (stage IV) hormone-responsive PCa diagnosed 18–42 months previously. Thematic analysis was undertaken using a framework approach.
Results
Most participants perceived their QoL to be relatively good, which was influenced by the following factors (enablers to ‘living well’ with PCa): a sense of connectedness to others, engagement in meaningful activities, resources (social, cognitive, financial), ability to manage uncertainty, utilization of adjustment strategies and support, communication and information from health professionals. Barriers to ‘living well’ with PCa were often the converse of these factors. These also included more troublesome PCa-related symptoms and stronger perceptions of loss and restriction.
Conclusions
In our study, men living with advanced hormone-responsive PCa often reported a good QoL. Exploring the influences on QoL in men with advanced PCa indicates how future interventions might improve the QoL of men who are struggling. Further research is required to develop and test interventions that enhance QoL for these men.
Advanced, Health care, Metastatic prostate cancer, Patient experience, Qualitative, Quality of life
Matheson, Lauren
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Nayoan, Jo
66cd893d-dbe1-4a10-a966-c817f734967f
Rivas, Carol
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Brett, Jo
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Wright, Penny
be58e744-69be-48f8-a416-8e543af1ad7b
Butcher, Hugh
ba20526e-5613-40e3-9659-df8d23c3bde3
Jordan, Paul
37812223-4611-4bf1-a59b-e02d085a71f1
Gavin, Anna
e887a323-7787-4455-82f7-531198db885d
Glaser, Adam
47f40b4c-2ff7-4c0e-a137-67564d0c29bc
Mason, Malcolm
df59220e-7dd8-466b-855d-37fbda6b5597
Wagland, Richard
16a44dcc-29cd-4797-9af2-41ef87f64d08
Watson, Eila
d295228d-d534-4c35-844f-ca8471c169c0
Matheson, Lauren
4e548e54-983a-4c9e-ae99-22423ffeb69c
Nayoan, Jo
66cd893d-dbe1-4a10-a966-c817f734967f
Rivas, Carol
040bfbc1-0aef-4826-ab58-e85743fea9d4
Brett, Jo
0b0cee91-6b1a-48d7-83e5-a58bb1472bd7
Wright, Penny
be58e744-69be-48f8-a416-8e543af1ad7b
Butcher, Hugh
ba20526e-5613-40e3-9659-df8d23c3bde3
Jordan, Paul
37812223-4611-4bf1-a59b-e02d085a71f1
Gavin, Anna
e887a323-7787-4455-82f7-531198db885d
Glaser, Adam
47f40b4c-2ff7-4c0e-a137-67564d0c29bc
Mason, Malcolm
df59220e-7dd8-466b-855d-37fbda6b5597
Wagland, Richard
16a44dcc-29cd-4797-9af2-41ef87f64d08
Watson, Eila
d295228d-d534-4c35-844f-ca8471c169c0
Matheson, Lauren, Nayoan, Jo, Rivas, Carol, Brett, Jo, Wright, Penny, Butcher, Hugh, Jordan, Paul, Gavin, Anna, Glaser, Adam, Mason, Malcolm, Wagland, Richard and Watson, Eila
(2020)
Strategies for living well with hormone-responsive advanced prostate cancer—a qualitative exploration.
Supportive Care in Cancer.
(doi:10.1007/s00520-020-05594-8).
Abstract
Purpose
Due to recent treatment advances, men are increasingly living longer with advanced prostate cancer (PCa). This study sought to understand men’s experiences of living with and adjusting to advanced hormone-responsive PCa and how this influenced their quality of life (QoL), in order to highlight how support could be optimized.
Methods
Participants were recruited through a UK wide survey—the ‘Life After Prostate Cancer Diagnosis’ study. In-depth telephone interviews were conducted with 24 men (aged 46–77 years) with advanced (stage IV) hormone-responsive PCa diagnosed 18–42 months previously. Thematic analysis was undertaken using a framework approach.
Results
Most participants perceived their QoL to be relatively good, which was influenced by the following factors (enablers to ‘living well’ with PCa): a sense of connectedness to others, engagement in meaningful activities, resources (social, cognitive, financial), ability to manage uncertainty, utilization of adjustment strategies and support, communication and information from health professionals. Barriers to ‘living well’ with PCa were often the converse of these factors. These also included more troublesome PCa-related symptoms and stronger perceptions of loss and restriction.
Conclusions
In our study, men living with advanced hormone-responsive PCa often reported a good QoL. Exploring the influences on QoL in men with advanced PCa indicates how future interventions might improve the QoL of men who are struggling. Further research is required to develop and test interventions that enhance QoL for these men.
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More information
Accepted/In Press date: 23 June 2020
e-pub ahead of print date: 6 July 2020
Additional Information:
Funding Information:
The Life After Prostate Cancer Diagnosis study was funded by the Movember Foundation, in partnership with Prostate Cancer UK, as part of the Prostate Cancer Outcomes programme, grant number BO26/MO.
Funding Information:
The authors thank all the men who responded to the survey. We thank the Movember Foundation, in partnership with Prostate Cancer UK, for funding the study. We acknowledge the following people for their contribution to the development, setting up and running of the study: Rebecca Mottram, Majorie Allen, Heather Kinnear, Conan Donnelly, Oonagh McSorley, Victoria Cairnduff, Linda Roberts, Adrian Slater, Picker Institute Europe, the LAPCD User Advisory Group and Clinical and Scientific Advisory Group. This study is based in part on information collected and quality assured by the National Cancer Registration and Analysis Service (part of Public Health England), the Northern Ireland Cancer Registry, the Welsh Cancer Intelligence & Surveillance Unit and the Scottish Cancer Registry (part of the Public Health & Intelligence Unit of NHS National Services Scotland).The work of cancer registries uses data provided by patients and collected by health services as part of their care and support.
Publisher Copyright:
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
Keywords:
Advanced, Health care, Metastatic prostate cancer, Patient experience, Qualitative, Quality of life
Identifiers
Local EPrints ID: 444224
URI: http://eprints.soton.ac.uk/id/eprint/444224
ISSN: 0941-4355
PURE UUID: 6e23011e-3752-4feb-bc1f-748ba14206e1
Catalogue record
Date deposited: 01 Oct 2020 16:34
Last modified: 17 Mar 2024 03:20
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Contributors
Author:
Lauren Matheson
Author:
Jo Nayoan
Author:
Carol Rivas
Author:
Jo Brett
Author:
Penny Wright
Author:
Hugh Butcher
Author:
Paul Jordan
Author:
Anna Gavin
Author:
Adam Glaser
Author:
Malcolm Mason
Author:
Eila Watson
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