The University of Southampton
University of Southampton Institutional Repository

Association between dietary patterns and renal function in a cross-sectional study using baseline data from the ELSA-Brasil cohort

Association between dietary patterns and renal function in a cross-sectional study using baseline data from the ELSA-Brasil cohort
Association between dietary patterns and renal function in a cross-sectional study using baseline data from the ELSA-Brasil cohort

Previous analyses of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) identified four main dietary patterns (DP). The aim of this study was to explore the association between the previously defined DP and renal function (RF). A cross-sectional study using the ELSA-Brasil baseline data was carried out. DP ("traditional", "fruits and vegetables", "bakery", and "low sugar/low fat), metabolic syndrome (MS) using the Joint Interim Statement criteria, microalbuminuria (MA), and glomerular filtration rate (eGFR) through the CKD-EPI equation were evaluated. Abnormal RF was defined as eGFR<60 mL·min-1·(1.73 m2)-1 and MA≥3.0 mg/dL. Factors associated with RF were determined and mediation analysis was performed to investigate the association between DP, MS, and RF. A total of 15,105 participants were recruited, with a mean age of 52±9 years; 8,134 participants (54%) were females. The mediation analysis identified indirect associations between "bakery" and "fruits and vegetables", and both were associated with decreased eGFR and albuminuria in both genders, compared with "traditional" and "low sugar/low fat" patterns in the general population. There was a direct association of the "bakery" pattern with MA in men (OR: 1.17, 95%CI: 1.92-1.48). The "fruits and vegetables" pattern also showed a direct association with reduced eGFR in women (OR: 1.65, 95%CI: 1.28-2.12), although there was no significance after adjustment. The "fruits and vegetables" and "bakery" DPs were associated with renal dysfunction. The only independent, direct association was between "bakery" DP and MA in men, raising concerns about DP and renal damage in men.

Albuminuria, Dietary pattern, Feeding behavior, Glomerular filtration rate, Kidney diseases
0100-879X
1-9
Silva Junior, Geraldo
d9a38364-e9b7-4436-8341-1f5361412f67
Fraser, Simon
135884b6-8737-4e8a-a98c-5d803ac7a2dc
Xavier, Rosa
2b7f8a33-e449-4e97-8410-5993c89f6c45
Mota, Rosa
c7d1f24d-ec99-4f56-b363-b6e2935fbf61
Lopes, Antonio
650f6744-8869-4ab8-ab32-ea2bbddc3b53
Mill, Jose
325dce40-efa6-4524-a426-53ae886144ac
Barreto, Sandhi
5fc91c63-922b-4534-8bad-5576f5335a6c
Luft, Vivian
422d135d-1446-4216-ac06-dbaab020c3a8
Chor, Dora
ae1db94b-bf12-4875-a8f5-9668e5bb641f
Santos, Carlos
16c39bb4-7ea3-4537-b0d7-59a1711cc5ab
Lotufo, Paulo
36939747-088c-47b8-a2dc-af452a60a1ff
Matos, Sheila
d1839cbe-9a86-4e45-ac46-40fc749aab2f
Silva Junior, Geraldo
d9a38364-e9b7-4436-8341-1f5361412f67
Fraser, Simon
135884b6-8737-4e8a-a98c-5d803ac7a2dc
Xavier, Rosa
2b7f8a33-e449-4e97-8410-5993c89f6c45
Mota, Rosa
c7d1f24d-ec99-4f56-b363-b6e2935fbf61
Lopes, Antonio
650f6744-8869-4ab8-ab32-ea2bbddc3b53
Mill, Jose
325dce40-efa6-4524-a426-53ae886144ac
Barreto, Sandhi
5fc91c63-922b-4534-8bad-5576f5335a6c
Luft, Vivian
422d135d-1446-4216-ac06-dbaab020c3a8
Chor, Dora
ae1db94b-bf12-4875-a8f5-9668e5bb641f
Santos, Carlos
16c39bb4-7ea3-4537-b0d7-59a1711cc5ab
Lotufo, Paulo
36939747-088c-47b8-a2dc-af452a60a1ff
Matos, Sheila
d1839cbe-9a86-4e45-ac46-40fc749aab2f

Silva Junior, Geraldo, Fraser, Simon, Xavier, Rosa, Mota, Rosa, Lopes, Antonio, Mill, Jose, Barreto, Sandhi, Luft, Vivian, Chor, Dora, Santos, Carlos, Lotufo, Paulo and Matos, Sheila (2020) Association between dietary patterns and renal function in a cross-sectional study using baseline data from the ELSA-Brasil cohort. Brazilian Journal of Medical and Biological Research, 53 (12), 1-9, [e10230]. (doi:10.1590/1414-431X202010230).

Record type: Article

Abstract

Previous analyses of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) identified four main dietary patterns (DP). The aim of this study was to explore the association between the previously defined DP and renal function (RF). A cross-sectional study using the ELSA-Brasil baseline data was carried out. DP ("traditional", "fruits and vegetables", "bakery", and "low sugar/low fat), metabolic syndrome (MS) using the Joint Interim Statement criteria, microalbuminuria (MA), and glomerular filtration rate (eGFR) through the CKD-EPI equation were evaluated. Abnormal RF was defined as eGFR<60 mL·min-1·(1.73 m2)-1 and MA≥3.0 mg/dL. Factors associated with RF were determined and mediation analysis was performed to investigate the association between DP, MS, and RF. A total of 15,105 participants were recruited, with a mean age of 52±9 years; 8,134 participants (54%) were females. The mediation analysis identified indirect associations between "bakery" and "fruits and vegetables", and both were associated with decreased eGFR and albuminuria in both genders, compared with "traditional" and "low sugar/low fat" patterns in the general population. There was a direct association of the "bakery" pattern with MA in men (OR: 1.17, 95%CI: 1.92-1.48). The "fruits and vegetables" pattern also showed a direct association with reduced eGFR in women (OR: 1.65, 95%CI: 1.28-2.12), although there was no significance after adjustment. The "fruits and vegetables" and "bakery" DPs were associated with renal dysfunction. The only independent, direct association was between "bakery" DP and MA in men, raising concerns about DP and renal damage in men.

Text
da_Silva_ELSA_CKD_BJMBR - Accepted Manuscript
Available under License Creative Commons Attribution.
Download (799kB)
Text
1414-431X-bjmbr-53-12-e10230 - Version of Record
Available under License Creative Commons Attribution.
Download (489kB)

More information

Accepted/In Press date: 24 July 2020
e-pub ahead of print date: 30 October 2020
Published date: 2020
Additional Information: Funding Information: We would like to thank all participants of the ELSA-Brasil study for their valuable voluntary contribution and the technical support from the employees of our institutions. This study was supported by the Brazilian Ministry of Health (Department of Science and Technology) and Ministry of Science, Technology and Innovation (FINEP, Financiadora de Estudos e Projetos), grants #01 06 0010.00, #01 06 0212.00, #01 060300.00, #01 06 0278.00, #01 06 0115.00, and #01 06 0071.00, CNPq (National Council for Scientific and Technological Development), and CAPES (Brazilian Post-Graduation Coordination). GBSJ received a grant from CNPq (grant #150368/2015-1). Publisher Copyright: © 2020, Associacao Brasileira de Divulgacao Cientifica. All rights reserved.
Keywords: Albuminuria, Dietary pattern, Feeding behavior, Glomerular filtration rate, Kidney diseases

Identifiers

Local EPrints ID: 444294
URI: http://eprints.soton.ac.uk/id/eprint/444294
ISSN: 0100-879X
PURE UUID: 54dd3c64-598e-4280-9b82-00e85a7b0818
ORCID for Simon Fraser: ORCID iD orcid.org/0000-0002-4172-4406

Catalogue record

Date deposited: 09 Oct 2020 16:33
Last modified: 06 Jun 2024 04:03

Export record

Altmetrics

Contributors

Author: Geraldo Silva Junior
Author: Simon Fraser ORCID iD
Author: Rosa Xavier
Author: Rosa Mota
Author: Antonio Lopes
Author: Jose Mill
Author: Sandhi Barreto
Author: Vivian Luft
Author: Dora Chor
Author: Carlos Santos
Author: Paulo Lotufo
Author: Sheila Matos

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×