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Noninvasive ventilation for COVID-19-associated acute hypoxaemic respiratory failure: experience from a single centre

Noninvasive ventilation for COVID-19-associated acute hypoxaemic respiratory failure: experience from a single centre
Noninvasive ventilation for COVID-19-associated acute hypoxaemic respiratory failure: experience from a single centre
Editor—In a minority of coronavirus disease 2019 (COVID-19) patients, severe acute hypoxaemic respiratory failure (AHRF) necessitates admission to an ICU for invasive mechanical ventilation with an associated mortality of >50%.1, 2, 3 Published cohorts suggest that noninvasive ventilation is a commonly used intervention in COVID-19-related AHRF4,5 although no formal evaluation has been reported in the setting of a clinical trial. It is uncertain whether noninvasive ventilation is beneficial or harmful for patients with COVID-19. Here, we report a single centre experience of the role of noninvasive ventilation in patients with respiratory failure associated with COVID-19.
Acute Disease, Adolescent, Adult, Aged, COVID-19, Cohort Studies, Coronavirus Infections/complications, Critical Care/methods, Female, Humans, Hypoxia/etiology, Male, Middle Aged, Noninvasive Ventilation/adverse effects, Pandemics, Pneumonia, Viral/complications, Respiration, Artificial/adverse effects, Respiratory Insufficiency/etiology, Young Adult
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e368-e371
Sivaloganathan, Arjjana A.
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Nasim-Mohi, Myra
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Brown, Michael M.
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Abdul, Nabil
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Jackson, Alexander
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Fletcher, Sophie V.
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Gupta, Sanjay
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Grocott, Michael P.W.
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Dushianthan, Ahilanandan
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Stewart, Michael
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Dushianthan, Ahilanadan
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Chambers, Robert
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Tanser, Suzie
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Fennell, Jonathan
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Celinski, Michael
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Nicholson-Robert, Timothy
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Wakatsuki, Mai
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Elkington, Paul
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Allenby, Mark
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Dennison, Paddy
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Lekkas, Anastasios
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Sivaloganathan, Arjjana
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Land, David
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Fletcher, Sophie
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Wilkinson,
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Freeman, Anna
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Burke, Hannah
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Faust, Saul
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Thomas, Gareth
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Kipps, Christopher
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University Hospital Southampton Critical Care and Respiratory Medicine Teams and the REACT investigators
Sivaloganathan, Arjjana A.
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Nasim-Mohi, Myra
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Brown, Michael M.
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Abdul, Nabil
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Jackson, Alexander
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Fletcher, Sophie V.
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Gupta, Sanjay
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Grocott, Michael P.W.
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Dushianthan, Ahilanandan
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Nixon, Julian
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Stewart, Michael
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Dushianthan, Ahilanadan
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Sparkes, David
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Chambers, Robert
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Celinski, Michael
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Elkington, Paul
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Allenby, Mark
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Lekkas, Anastasios
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Sivaloganathan, Arjjana
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Land, David
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Fletcher, Sophie
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Burke, Hannah
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Faust, Saul
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Thomas, Gareth
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Kipps, Christopher
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Sivaloganathan, Arjjana A., Nasim-Mohi, Myra, Brown, Michael M., Abdul, Nabil, Jackson, Alexander, Fletcher, Sophie V., Gupta, Sanjay and Dushianthan, Ahilanandan , University Hospital Southampton Critical Care and Respiratory Medicine Teams and the REACT investigators (2020) Noninvasive ventilation for COVID-19-associated acute hypoxaemic respiratory failure: experience from a single centre. British Journal of Anaesthesia, 125 (4), e368-e371. (doi:10.1016/j.bja.2020.07.008).

Record type: Letter

Abstract

Editor—In a minority of coronavirus disease 2019 (COVID-19) patients, severe acute hypoxaemic respiratory failure (AHRF) necessitates admission to an ICU for invasive mechanical ventilation with an associated mortality of >50%.1, 2, 3 Published cohorts suggest that noninvasive ventilation is a commonly used intervention in COVID-19-related AHRF4,5 although no formal evaluation has been reported in the setting of a clinical trial. It is uncertain whether noninvasive ventilation is beneficial or harmful for patients with COVID-19. Here, we report a single centre experience of the role of noninvasive ventilation in patients with respiratory failure associated with COVID-19.

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More information

Accepted/In Press date: 14 July 2020
e-pub ahead of print date: 21 July 2020
Published date: 16 September 2020
Keywords: Acute Disease, Adolescent, Adult, Aged, COVID-19, Cohort Studies, Coronavirus Infections/complications, Critical Care/methods, Female, Humans, Hypoxia/etiology, Male, Middle Aged, Noninvasive Ventilation/adverse effects, Pandemics, Pneumonia, Viral/complications, Respiration, Artificial/adverse effects, Respiratory Insufficiency/etiology, Young Adult
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Identifiers

Local EPrints ID: 444537
URI: http://eprints.soton.ac.uk/id/eprint/444537
DOI: doi:10.1016/j.bja.2020.07.008
ISSN: 0007-0912
PURE UUID: 9bbaee61-126b-4c55-a149-615032b4869a
ORCID for Alexander Jackson: ORCID iD orcid.org/0000-0002-3153-9231
ORCID for Michael P.W. Grocott: ORCID iD orcid.org/0000-0002-9484-7581
ORCID for Ahilanandan Dushianthan: ORCID iD orcid.org/0000-0002-0165-3359
ORCID for Ahilanadan Dushianthan: ORCID iD orcid.org/0000-0002-0165-3359
ORCID for Rebecca Cusack: ORCID iD orcid.org/0000-0003-2863-2870
ORCID for Mark Jones: ORCID iD orcid.org/0000-0001-6308-6014
ORCID for Paul Elkington: ORCID iD orcid.org/0000-0003-0390-0613
ORCID for Hannah Burke: ORCID iD orcid.org/0000-0003-3553-4590
ORCID for Saul Faust: ORCID iD orcid.org/0000-0003-3410-7642
ORCID for Christopher Kipps: ORCID iD orcid.org/0000-0002-5205-9712

Catalogue record

Date deposited: 23 Oct 2020 16:31
Last modified: 23 Apr 2024 01:55

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Contributors

Author: Arjjana A. Sivaloganathan
Author: Myra Nasim-Mohi
Author: Michael M. Brown
Author: Nabil Abdul
Author: Alexander Jackson ORCID iD
Author: Sophie V. Fletcher
Author: Sanjay Gupta
Author: Michael P.W. Grocott ORCID iD
Author: Ahilanandan Dushianthan ORCID iD
Author: Julian Nixon
Author: Denny ZH Levett
Author: Michael Stewart
Author: Ahilanadan Dushianthan ORCID iD
Author: David Sparkes
Author: Robert Chambers
Author: Kathleen Nolan
Author: Suzie Tanser
Author: Jonathan Fennell
Author: Michael Celinski
Author: Dominic Richardson
Author: Rebecca Cusack ORCID iD
Author: Benjamin Skinner
Author: Timothy Nicholson-Robert
Author: Mai Wakatsuki
Author: Ben Thomas
Author: Francois Wessels
Author: Mark Jones ORCID iD
Author: Paul Elkington ORCID iD
Author: Tom Wilkinson
Author: Mark Allenby
Author: Thomas Daniels
Author: Paddy Dennison
Author: Anastasios Lekkas
Author: Arjjana Sivaloganathan
Author: David Land
Author: Sophie Fletcher
Author: Wilkinson
Author: Anna Freeman
Author: Hannah Burke ORCID iD
Author: Saul Faust ORCID iD
Author: Gareth Thomas
Author: Christopher Kipps ORCID iD
Corporate Author: University Hospital Southampton Critical Care and Respiratory Medicine Teams and the REACT investigators

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