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Enantioselective synthesis and selective monofunctionalization of (4R,6R)-4,6-dihydroxy-2,8-dioxabicyclo[3.3.0]octane

Enantioselective synthesis and selective monofunctionalization of (4R,6R)-4,6-dihydroxy-2,8-dioxabicyclo[3.3.0]octane
Enantioselective synthesis and selective monofunctionalization of (4R,6R)-4,6-dihydroxy-2,8-dioxabicyclo[3.3.0]octane
An efficient, enantioselective synthesis of a disubstituted bis-THF scaffold 5 is described, as well as an efficient differentiation of the 1,3-diol unit.
hiv protease inhibitors, stereocontrolled synthesis, aspergillus-stellatus, furofurans, metathesis, mycotoxin, arabitol
1523-7060
5821-5824
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Jeffery, Martin J.
4d9d91dc-9d4d-4063-8d72-35db99db3967
Josse, Solen
512a0636-acc9-41fa-a587-152bd8ca13b5
Tomassi, Cyrille
51fbf42e-4b91-481c-8528-95ca06e30c40
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Jeffery, Martin J.
4d9d91dc-9d4d-4063-8d72-35db99db3967
Josse, Solen
512a0636-acc9-41fa-a587-152bd8ca13b5
Tomassi, Cyrille
51fbf42e-4b91-481c-8528-95ca06e30c40

Linclau, Bruno, Jeffery, Martin J., Josse, Solen and Tomassi, Cyrille (2006) Enantioselective synthesis and selective monofunctionalization of (4R,6R)-4,6-dihydroxy-2,8-dioxabicyclo[3.3.0]octane. Organic Letters, 8 (25), 5821-5824. (doi:10.1021/ol062431d).

Record type: Article

Abstract

An efficient, enantioselective synthesis of a disubstituted bis-THF scaffold 5 is described, as well as an efficient differentiation of the 1,3-diol unit.

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More information

Published date: 2006
Keywords: hiv protease inhibitors, stereocontrolled synthesis, aspergillus-stellatus, furofurans, metathesis, mycotoxin, arabitol

Identifiers

Local EPrints ID: 44490
URI: http://eprints.soton.ac.uk/id/eprint/44490
ISSN: 1523-7060
PURE UUID: 2e1ff1ca-8610-4110-acec-8993356599e0
ORCID for Bruno Linclau: ORCID iD orcid.org/0000-0001-8762-0170

Catalogue record

Date deposited: 06 Mar 2007
Last modified: 16 Mar 2024 03:15

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Contributors

Author: Bruno Linclau ORCID iD
Author: Martin J. Jeffery
Author: Solen Josse
Author: Cyrille Tomassi

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