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CD96-binding agent used in treatment of disease in patient, where disease is cancer or infectious disease, and treatment is monotherapy, is capable of stimulating activation and/or proliferation of T cells upon binding to CD96

CD96-binding agent used in treatment of disease in patient, where disease is cancer or infectious disease, and treatment is monotherapy, is capable of stimulating activation and/or proliferation of T cells upon binding to CD96
CD96-binding agent used in treatment of disease in patient, where disease is cancer or infectious disease, and treatment is monotherapy, is capable of stimulating activation and/or proliferation of T cells upon binding to CD96
NOVELTY - CD96-binding agent is capable of stimulating activation and/or proliferation of T cells upon binding to CD96.

USE - CD96-binding agent used in treatment of a disease in a patient, where the disease is a cancer or an infectious disease, and treatment is a monotherapy, or combination therapy, and used in combination with a co-stimulating agent or an immune checkpoint inhibitor in particular a T cell co-stimulating agent or an immune checkpoint inhibitor, for stimulation of the activation and/or proliferation of T cells upon binding to CD96, and used as an adjuvant in a prophylactic or therapeutic vaccine (all claimed).

DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following:

(1) an isolated nucleic acid, which encodes the amino acid sequence of the CD96-binding agent;

(2) an isolated cell that produces the CD96-binding agent; and

(3) a pharmaceutical composition, which comprises the CD96-binding agent and a pharmaceutical acceptable excipient or carrier.
WO2019030377-A1
Renart-Depontieu, Florence
d215b05e-d068-4af1-ae6a-8cf47c83d37c
Takami, Sachiko
7e8d2116-b88b-49c3-98be-f4a49dd17307
Margall-Ducos, Germain
293aea58-9b67-4263-ba0d-d302d44603b3
Beltraminelli, Nicola
0f5381de-70f3-4b74-8df4-3b0c40059876
Garrone, Pierre
9191da89-2328-4af3-b301-b6eddc8f5773
Rogel, Anne
526dbdea-618a-415d-907d-726a8cbe3833
Al-Shamkhani, Aymen
0a40b3ce-9d71-4d41-9369-7212f0a84504
Preville, Xavier
c329385f-698f-4022-86c1-431b864787bb

Renart-Depontieu, Florence, Takami, Sachiko, Margall-Ducos, Germain, Beltraminelli, Nicola, Garrone, Pierre, Rogel, Anne, Al-Shamkhani, Aymen and Preville, Xavier (Inventors) (2019) CD96-binding agent used in treatment of disease in patient, where disease is cancer or infectious disease, and treatment is monotherapy, is capable of stimulating activation and/or proliferation of T cells upon binding to CD96. WO2019030377-A1.

Record type: Patent

Abstract

NOVELTY - CD96-binding agent is capable of stimulating activation and/or proliferation of T cells upon binding to CD96.

USE - CD96-binding agent used in treatment of a disease in a patient, where the disease is a cancer or an infectious disease, and treatment is a monotherapy, or combination therapy, and used in combination with a co-stimulating agent or an immune checkpoint inhibitor in particular a T cell co-stimulating agent or an immune checkpoint inhibitor, for stimulation of the activation and/or proliferation of T cells upon binding to CD96, and used as an adjuvant in a prophylactic or therapeutic vaccine (all claimed).

DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following:

(1) an isolated nucleic acid, which encodes the amino acid sequence of the CD96-binding agent;

(2) an isolated cell that produces the CD96-binding agent; and

(3) a pharmaceutical composition, which comprises the CD96-binding agent and a pharmaceutical acceptable excipient or carrier.

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More information

Published date: 14 February 2019

Identifiers

Local EPrints ID: 445127
URI: http://eprints.soton.ac.uk/id/eprint/445127
PURE UUID: 3b1ba0b2-9982-4a2d-bcf4-fc651d2d3572
ORCID for Aymen Al-Shamkhani: ORCID iD orcid.org/0000-0003-0727-4189

Catalogue record

Date deposited: 20 Nov 2020 17:32
Last modified: 18 Feb 2021 16:51

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Contributors

Inventor: Florence Renart-Depontieu
Inventor: Sachiko Takami
Inventor: Germain Margall-Ducos
Inventor: Nicola Beltraminelli
Inventor: Pierre Garrone
Inventor: Anne Rogel
Inventor: Aymen Al-Shamkhani ORCID iD
Inventor: Xavier Preville

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