The University of Southampton
×
Filter your search:
University of Southampton Institutional Repository

Sensitive detection of SARS-CoV-2-specific antibodies in dried blood spot samples

Sensitive detection of SARS-CoV-2-specific antibodies in dried blood spot samples
Sensitive detection of SARS-CoV-2-specific antibodies in dried blood spot samples

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.

COVID-19, DBS, SARS-CoV-2, antibody, coronavirus disease, dried blood spot, respiratory infections, severe acute respiratory syndrome coronavirus 2, viruses, zoonoses
1080-6059
2970-2973
Morley, Gabriella L
4d8abfbe-8b0a-4a8e-81b0-ce8d2014695a
Jossi, Sian
b6e73f03-47eb-47f1-9c62-d9cfb71c280b
Perez-Toledo, Marisol
db9dfcc0-d3a0-4c9d-9606-f2370574e3d3
Faustini, Sian E
fc25e886-bb2c-4c9c-a421-df8e00e6b1ba
Marcial-Juarez, Edith
071ab53d-fb37-49fd-b467-4448692adab3
Shields, Adrian M
2c945fb6-b12f-487d-8b6b-bbdd321a13db
Goodall, Margaret
27208c10-af66-47b3-b23d-57b343e27868
Allen, Joel D
c89d5569-7659-4835-b535-c9586e956b3a
Watanabe, Yasunori
8c0ee4af-a293-4de5-9036-3ce2051b380c
Newby, Maddy L
417cba47-6a6f-42b9-8b9c-640f0518c621
Crispin, Max
cd980957-0943-4b89-b2b2-710f01f33bc9
Drayson, Mark T
282a00f4-8edf-4075-a83c-272ffcce53e8
Cunningham, Adam F
63973765-dcc3-4a66-bd15-e0d774484b74
Richter, Alex G
a8d5bc53-c51b-463d-af6b-ca8b8a5412d0
O'Shea, Matthew K
5371d186-3291-4b54-8dfd-ec3b71601311
Morley, Gabriella L
4d8abfbe-8b0a-4a8e-81b0-ce8d2014695a
Jossi, Sian
b6e73f03-47eb-47f1-9c62-d9cfb71c280b
Perez-Toledo, Marisol
db9dfcc0-d3a0-4c9d-9606-f2370574e3d3
Faustini, Sian E
fc25e886-bb2c-4c9c-a421-df8e00e6b1ba
Marcial-Juarez, Edith
071ab53d-fb37-49fd-b467-4448692adab3
Shields, Adrian M
2c945fb6-b12f-487d-8b6b-bbdd321a13db
Goodall, Margaret
27208c10-af66-47b3-b23d-57b343e27868
Allen, Joel D
c89d5569-7659-4835-b535-c9586e956b3a
Watanabe, Yasunori
8c0ee4af-a293-4de5-9036-3ce2051b380c
Newby, Maddy L
417cba47-6a6f-42b9-8b9c-640f0518c621
Crispin, Max
cd980957-0943-4b89-b2b2-710f01f33bc9
Drayson, Mark T
282a00f4-8edf-4075-a83c-272ffcce53e8
Cunningham, Adam F
63973765-dcc3-4a66-bd15-e0d774484b74
Richter, Alex G
a8d5bc53-c51b-463d-af6b-ca8b8a5412d0
O'Shea, Matthew K
5371d186-3291-4b54-8dfd-ec3b71601311

Morley, Gabriella L, Jossi, Sian, Perez-Toledo, Marisol, Faustini, Sian E, Marcial-Juarez, Edith, Shields, Adrian M, Goodall, Margaret, Allen, Joel D, Watanabe, Yasunori, Newby, Maddy L, Crispin, Max, Drayson, Mark T, Cunningham, Adam F, Richter, Alex G and O'Shea, Matthew K (2020) Sensitive detection of SARS-CoV-2-specific antibodies in dried blood spot samples. Emerging Infectious Diseases, 26 (12), 2970-2973. (doi:10.3201/eid2612.203309).

Record type: Article

Abstract

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.

Text
Sensitive Detection of SARS-CoV-2–Specific - Version of Record
Available under License Creative Commons Attribution.
Download (719kB)

More information

e-pub ahead of print date: 24 September 2020
Published date: 1 December 2020
Keywords: COVID-19, DBS, SARS-CoV-2, antibody, coronavirus disease, dried blood spot, respiratory infections, severe acute respiratory syndrome coronavirus 2, viruses, zoonoses
Learn more about Institute for Life Sciences research

Identifiers

Local EPrints ID: 445471
URI: http://eprints.soton.ac.uk/id/eprint/445471
DOI: doi:10.3201/eid2612.203309
ISSN: 1080-6059
PURE UUID: dc90d5d1-700d-458b-a628-135d73de2ce9
ORCID for Joel D Allen: ORCID iD orcid.org/0000-0003-2547-968X
ORCID for Max Crispin: ORCID iD orcid.org/0000-0002-1072-2694

Catalogue record

Date deposited: 10 Dec 2020 17:31
Last modified: 17 Mar 2024 04:09

Export record

Altmetrics

Contributors

Author: Gabriella L Morley
Author: Sian Jossi
Author: Marisol Perez-Toledo
Author: Sian E Faustini
Author: Edith Marcial-Juarez
Author: Adrian M Shields
Author: Margaret Goodall
Author: Joel D Allen ORCID iD
Author: Yasunori Watanabe
Author: Maddy L Newby
Author: Max Crispin ORCID iD
Author: Mark T Drayson
Author: Adam F Cunningham
Author: Alex G Richter
Author: Matthew K O'Shea

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Library staff additional information
Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×