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Allocation of funding into blast injury-related research and blast traumatic brain injury between 2000 and 2019: analysis of global investments from public and philanthropic funders

Allocation of funding into blast injury-related research and blast traumatic brain injury between 2000 and 2019: analysis of global investments from public and philanthropic funders
Allocation of funding into blast injury-related research and blast traumatic brain injury between 2000 and 2019: analysis of global investments from public and philanthropic funders

INTRODUCTION: There is little systematic tracking or detailed analysis of investments in research and development for blast injury to support decision-making around research future funding.

METHODS: This study examined global investments into blast injury-related research from public and philanthropic funders across 2000-2019. Research databases were searched using keywords, and open data were extracted from funder websites. Data collected included study title, abstract, award amount, funder and year. Individual awards were categorised to compare amounts invested into different blast injuries, the scientific approaches taken and analysis of research investment into blast traumatic brain injury (TBI).

RESULTS: A total of 806 awards were identified into blast injury-related research globally, equating to US$902.1 million (m, £565.9m GBP). There was a general increase in year-on-year investment between 2003 and 2009 followed by a consistent decline in annual funding since 2010. Pre-clinical research received $671.3 m (74.4%) of investment. Brain-related injury research received $427.7 m (47.4%), orthopaedic injury $138.6 m (15.4%), eye injury $63.7 m (7.0%) and ear injury $60.5m (6.7%). Blast TBI research received a total investment of $384.3 m, representing 42.6% of all blast injury-related research. The U.S. Department of Defense funded $719.3 m (80%).

CONCLUSIONS: Investment data suggest that blast TBI research has received greater funding than other blast injury health areas. The funding pattern observed can be seen as reactive, driven by the response to the War on Terror, the rising profile of blast TBI and congressionally mandated research.

accident and emergency medicine, epidemiology, neurological injury, orthopaedic and trauma surgery, trauma management
2633-3775
1-6
Denny, Jack
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Brown, Rebecca
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Head, Michael
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Batchelor, James
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Dickinson, Alexander
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Denny, Jack
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Brown, Rebecca
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Head, Michael
67ce0afc-2fc3-47f4-acf2-8794d27ce69c
Batchelor, James
e53c36c7-aa7f-4fae-8113-30bfbb9b36ee
Dickinson, Alexander
10151972-c1b5-4f7d-bc12-6482b5870cad

Denny, Jack, Brown, Rebecca, Head, Michael, Batchelor, James and Dickinson, Alexander (2020) Allocation of funding into blast injury-related research and blast traumatic brain injury between 2000 and 2019: analysis of global investments from public and philanthropic funders. BMJ Military Health, 1-6. (doi:10.1136/bmjmilitary-2020-001655).

Record type: Article

Abstract

INTRODUCTION: There is little systematic tracking or detailed analysis of investments in research and development for blast injury to support decision-making around research future funding.

METHODS: This study examined global investments into blast injury-related research from public and philanthropic funders across 2000-2019. Research databases were searched using keywords, and open data were extracted from funder websites. Data collected included study title, abstract, award amount, funder and year. Individual awards were categorised to compare amounts invested into different blast injuries, the scientific approaches taken and analysis of research investment into blast traumatic brain injury (TBI).

RESULTS: A total of 806 awards were identified into blast injury-related research globally, equating to US$902.1 million (m, £565.9m GBP). There was a general increase in year-on-year investment between 2003 and 2009 followed by a consistent decline in annual funding since 2010. Pre-clinical research received $671.3 m (74.4%) of investment. Brain-related injury research received $427.7 m (47.4%), orthopaedic injury $138.6 m (15.4%), eye injury $63.7 m (7.0%) and ear injury $60.5m (6.7%). Blast TBI research received a total investment of $384.3 m, representing 42.6% of all blast injury-related research. The U.S. Department of Defense funded $719.3 m (80%).

CONCLUSIONS: Investment data suggest that blast TBI research has received greater funding than other blast injury health areas. The funding pattern observed can be seen as reactive, driven by the response to the War on Terror, the rising profile of blast TBI and congressionally mandated research.

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More information

Accepted/In Press date: 12 November 2020
e-pub ahead of print date: 26 November 2020
Additional Information: © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Keywords: accident and emergency medicine, epidemiology, neurological injury, orthopaedic and trauma surgery, trauma management

Identifiers

Local EPrints ID: 445473
URI: http://eprints.soton.ac.uk/id/eprint/445473
ISSN: 2633-3775
PURE UUID: 32bdac32-a71a-431c-9136-99cd61cc23f2
ORCID for Jack Denny: ORCID iD orcid.org/0000-0003-3181-4747
ORCID for Rebecca Brown: ORCID iD orcid.org/0000-0001-5825-6859
ORCID for Michael Head: ORCID iD orcid.org/0000-0003-1189-0531
ORCID for James Batchelor: ORCID iD orcid.org/0000-0002-5307-552X
ORCID for Alexander Dickinson: ORCID iD orcid.org/0000-0002-9647-1944

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Date deposited: 10 Dec 2020 17:31
Last modified: 17 Mar 2024 03:52

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Author: Jack Denny ORCID iD
Author: Rebecca Brown ORCID iD
Author: Michael Head ORCID iD
Author: James Batchelor ORCID iD

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