READ ME File For the following PhD thesis: Jennifer Bramley (2020) "Investigating the mechanisms of soft tissue damage at the residual limb-socket interface", University of Southampton, Faculty of Engineering & Physical Sciences. Dataset DOI: ReadMe Author: Jennifer Bramley, University of Southampton [ORCID ID- 0000-0003-0414-3984] This dataset supports the publication: AUTHOR- Bramley, J.L TITLE- Investigating the mechanisms of soft tissue damage at the residual limb-socket interface This dataset contains: An Excel spreadsheet containing the raw data behind the measurements taken during the above linked PhD thesis. These measurements include interface pressure, myoton stiffness, TCPO2, TCPCO2 and inflammatory response. For Magnetic Resonance Imaging data that was also collected as part of this PhD research (under ethical approval ERGO ID's 29696 and 41864) please contact rgoinfo@soton.ac.uk to obtain third party ethical approval to then get access to the MRI dataset from A. S. Dickinson, Bioengineering, Faculty of Engineering and Physical Sciences, University of Southampton, Highfield Campus, University Rd, Southampton, SO17 1BJ, UK, (Email: alex.dickinson@soton.ac.uk). The keys for the Excel sheets are as follows: This research involved the right limbs of 10 participants without amputation (control limbs) and both limbs of 10 participants with unilateral transtibial amputation (contralateral and residual limbs). Control- Limbs of individuals without amputation Contralateral- The contralateral limbs of individuals with amputation Resdiual- The residual limbs of individuals with amputation PT- Patellar Tendon Measurement Site LC- Lateral Calf Measurement Site PC- Posterior Calf Measurement Site TCPO2- Transcutaneous Oxygen Tension TCPCO2- Transcutaneous Carbon Dioxide Tension NOTE- Baseline for percentage change in TCPO2 and TCPCO2 is considered to be the average of the data point at cuff application and the 2 preceding data points. Date of data collection: 12/2018-09/2019 Information about geographic location of data collection: University of Southampton, U.K. Licence: Date that the file was created: 12, 2020