The University of Southampton
University of Southampton Institutional Repository

The cost of anal cancer in England: Retrospective hospital data analysis and Markov model

The cost of anal cancer in England: Retrospective hospital data analysis and Markov model
The cost of anal cancer in England: Retrospective hospital data analysis and Markov model

Background: Anal cancer requires a multidisciplinary approach to treatment with often complex interventions. Little is known regarding the associated costs and resource use. Methods: Patient records were extracted from a national hospital database to estimate the number of patients treated for anal cancer in England. Identified resource use was linked to published UK cost estimates to quantify the reimbursement of treatment through the Payment by Results system. A mathematical model was developed simultaneously to validate findings and to calculate the average 10-year cost of treating a squamous cell anal carcinoma case from diagnosis. The model utilised data from the Association of Coloproctology of Great Britain and Ireland's anal cancer position statement. Results: On average, 1,564 patients were admitted to hospital and 389 attended an outpatient facility per year. The average annual cost per inpatient and outpatient ranged from £4,562-£5,230 and £1,146-£1,335, respectively. Based on the model estimates, the inflated cost per case was between £16,470-£16,652. Results were most sensitive to the mode of admission for primary treatment and the costs of staging/diagnosis (inflated range: £14,309-£23,264). Conclusions: Despite limitations in the available data, these results indicate that the cost of treating anal cancer is significant. Further observational work is required in order to verify these findings.

Anal cancer, England, Reimbursement, Resource use
1471-2458
Keeping, Sam T.
d279412c-8d70-4442-ae7d-f695d7ad8209
Tempest, Michael J.
9ffd2e96-533a-494d-8245-a31c2e2c2f52
Stephens, Stephanie J.
6821cee4-b3e1-4973-aaa8-251829d900a3
Carroll, Stuart M.
cec10a7e-d8fe-443c-af2f-a44c4c1cb786
Nugent, Karen P.
79fcb89d-6ff2-47b8-ac2c-2afb24954456
O'Dwyer, Sarah T.
1e1f67b2-6386-4fcb-97b4-dd59bcbd084a
Keeping, Sam T.
d279412c-8d70-4442-ae7d-f695d7ad8209
Tempest, Michael J.
9ffd2e96-533a-494d-8245-a31c2e2c2f52
Stephens, Stephanie J.
6821cee4-b3e1-4973-aaa8-251829d900a3
Carroll, Stuart M.
cec10a7e-d8fe-443c-af2f-a44c4c1cb786
Nugent, Karen P.
79fcb89d-6ff2-47b8-ac2c-2afb24954456
O'Dwyer, Sarah T.
1e1f67b2-6386-4fcb-97b4-dd59bcbd084a

Keeping, Sam T., Tempest, Michael J., Stephens, Stephanie J., Carroll, Stuart M., Nugent, Karen P. and O'Dwyer, Sarah T. (2014) The cost of anal cancer in England: Retrospective hospital data analysis and Markov model. BMC Public Health, 14 (1), [1123]. (doi:10.1186/1471-2458-14-1123).

Record type: Article

Abstract

Background: Anal cancer requires a multidisciplinary approach to treatment with often complex interventions. Little is known regarding the associated costs and resource use. Methods: Patient records were extracted from a national hospital database to estimate the number of patients treated for anal cancer in England. Identified resource use was linked to published UK cost estimates to quantify the reimbursement of treatment through the Payment by Results system. A mathematical model was developed simultaneously to validate findings and to calculate the average 10-year cost of treating a squamous cell anal carcinoma case from diagnosis. The model utilised data from the Association of Coloproctology of Great Britain and Ireland's anal cancer position statement. Results: On average, 1,564 patients were admitted to hospital and 389 attended an outpatient facility per year. The average annual cost per inpatient and outpatient ranged from £4,562-£5,230 and £1,146-£1,335, respectively. Based on the model estimates, the inflated cost per case was between £16,470-£16,652. Results were most sensitive to the mode of admission for primary treatment and the costs of staging/diagnosis (inflated range: £14,309-£23,264). Conclusions: Despite limitations in the available data, these results indicate that the cost of treating anal cancer is significant. Further observational work is required in order to verify these findings.

This record has no associated files available for download.

More information

Published date: 31 October 2014
Keywords: Anal cancer, England, Reimbursement, Resource use

Identifiers

Local EPrints ID: 445636
URI: http://eprints.soton.ac.uk/id/eprint/445636
ISSN: 1471-2458
PURE UUID: 34fac571-ee6c-41f0-96e0-2d7bed5f9496

Catalogue record

Date deposited: 04 Jan 2021 17:35
Last modified: 16 Mar 2024 09:42

Export record

Altmetrics

Contributors

Author: Sam T. Keeping
Author: Michael J. Tempest
Author: Stephanie J. Stephens
Author: Stuart M. Carroll
Author: Karen P. Nugent
Author: Sarah T. O'Dwyer

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×