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A general route to protected quaternary ?-amino acids from ?-amino alcohols via a stereocontrolled radical approach

A general route to protected quaternary ?-amino acids from ?-amino alcohols via a stereocontrolled radical approach
A general route to protected quaternary ?-amino acids from ?-amino alcohols via a stereocontrolled radical approach
A radical-based approach facilitates the highly stereocontrolled functionalisation of ?-amino alcohols, opening up a new, generally applicable methodology for the preparation of quaternary ?-amino acids.
enantioselective synthesis, functionalization, translocation, alkylation
1359-7345
2983-2985
Wood, Mark E.
790e32fe-abef-42ca-b663-a23d8276e1e2
Penny, Mark J.
fd7291fa-601f-4725-acad-301fdc340a48
Steere, Jenny S.
2581342d-815d-4354-8545-678e31730165
Horton, Peter N.
154c8930-bfc3-495b-ad4a-8a278d5da3a5
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
Hursthouse, Michael B.
57a2ddf9-b1b3-4f38-bfe9-ef2f526388da
Wood, Mark E.
790e32fe-abef-42ca-b663-a23d8276e1e2
Penny, Mark J.
fd7291fa-601f-4725-acad-301fdc340a48
Steere, Jenny S.
2581342d-815d-4354-8545-678e31730165
Horton, Peter N.
154c8930-bfc3-495b-ad4a-8a278d5da3a5
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
Hursthouse, Michael B.
57a2ddf9-b1b3-4f38-bfe9-ef2f526388da

Wood, Mark E., Penny, Mark J., Steere, Jenny S., Horton, Peter N., Light, Mark E. and Hursthouse, Michael B. (2006) A general route to protected quaternary ?-amino acids from ?-amino alcohols via a stereocontrolled radical approach. Chemical Communications, (28), 2983-2985. (doi:10.1039/b604123j).

Record type: Article

Abstract

A radical-based approach facilitates the highly stereocontrolled functionalisation of ?-amino alcohols, opening up a new, generally applicable methodology for the preparation of quaternary ?-amino acids.

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More information

Published date: 2006
Keywords: enantioselective synthesis, functionalization, translocation, alkylation

Identifiers

Local EPrints ID: 44568
URI: http://eprints.soton.ac.uk/id/eprint/44568
ISSN: 1359-7345
PURE UUID: 5444b490-4bb8-49d9-827d-6c20d397f911
ORCID for Peter N. Horton: ORCID iD orcid.org/0000-0001-8886-2016
ORCID for Mark E. Light: ORCID iD orcid.org/0000-0002-0585-0843

Catalogue record

Date deposited: 28 Feb 2007
Last modified: 10 Sep 2019 00:49

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