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Nitrite catalyzes reductive nitrosylation of the water-soluble ferri-heme model FeIII(TPPS) to FeII(TPPS)(NO)

Nitrite catalyzes reductive nitrosylation of the water-soluble ferri-heme model FeIII(TPPS) to FeII(TPPS)(NO)
Nitrite catalyzes reductive nitrosylation of the water-soluble ferri-heme model FeIII(TPPS) to FeII(TPPS)(NO)

Quantitative investigation of the reaction of the ferri-heme model compound FeIII(TPPS)(H2O)2 (1) to give FeII(TPPS)(NO)(2) (TPPS = tetra(4-sulfonato-phenyl)porphinato) in buffered aqueous solution demonstrates a slow pH-independent reductive nitrosylation pathway in the pH range 4-6. The rate of this reaction is subject to modest general base catalysis. In the course of this study, a surprising catalytic pathway whereby nitrite ion (NO2-) strongly catalyzes the reduction of 1 to 2 under reductive nitrosylation conditions was demonstrated.

0020-1669
2-4
Fernandez, Bernadette O.
9890aabc-1fe6-4530-a51e-31182e537131
Lorković, Ivan M.
1372d52f-5b0c-40a0-b6d9-9278f88e4678
Ford, Peter C.
a752d252-18ac-4b00-8c4b-c36f28cf15df
Fernandez, Bernadette O.
9890aabc-1fe6-4530-a51e-31182e537131
Lorković, Ivan M.
1372d52f-5b0c-40a0-b6d9-9278f88e4678
Ford, Peter C.
a752d252-18ac-4b00-8c4b-c36f28cf15df

Fernandez, Bernadette O., Lorković, Ivan M. and Ford, Peter C. (2003) Nitrite catalyzes reductive nitrosylation of the water-soluble ferri-heme model FeIII(TPPS) to FeII(TPPS)(NO). Inorganic Chemistry, 42 (1), 2-4. (doi:10.1021/ic020519r).

Record type: Article

Abstract

Quantitative investigation of the reaction of the ferri-heme model compound FeIII(TPPS)(H2O)2 (1) to give FeII(TPPS)(NO)(2) (TPPS = tetra(4-sulfonato-phenyl)porphinato) in buffered aqueous solution demonstrates a slow pH-independent reductive nitrosylation pathway in the pH range 4-6. The rate of this reaction is subject to modest general base catalysis. In the course of this study, a surprising catalytic pathway whereby nitrite ion (NO2-) strongly catalyzes the reduction of 1 to 2 under reductive nitrosylation conditions was demonstrated.

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Published date: 1 January 2003

Identifiers

Local EPrints ID: 445697
URI: http://eprints.soton.ac.uk/id/eprint/445697
ISSN: 0020-1669
PURE UUID: 6ade318e-58a8-41a8-ace1-6370e7af354f
ORCID for Bernadette O. Fernandez: ORCID iD orcid.org/0000-0001-6337-0381

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Date deposited: 06 Jan 2021 17:40
Last modified: 17 Mar 2024 03:31

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Contributors

Author: Bernadette O. Fernandez ORCID iD
Author: Ivan M. Lorković
Author: Peter C. Ford

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