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Consensus on DEfinition of Food Allergy SEverity (DEFASE): protocol for a systematic review

Consensus on DEfinition of Food Allergy SEverity (DEFASE): protocol for a systematic review
Consensus on DEfinition of Food Allergy SEverity (DEFASE): protocol for a systematic review

Background and aims: The term "Food Allergy" refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current evidence relating to the severity of IgE-mediated food allergy; it will inform attempts to develop a consensus to define food allergy severity by clinicians and other stakeholders.

Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published studies. Studies will be independently screened against pre-defined eligibility criteria and critically appraised by established instruments. Data will be descriptively and, if possible and applicable, quantitatively synthesised.

Ethics and dissemination: This study does not require any specific ethical approval since it is a systematic review. We plan to report results from this systematic review in a peer reviewed journal. These results will be used to inform the development of an international consensus to define severe food allergy. Author's potential conflicts of interest are clearly stated.

PROSPERO registration number: CRD42020183103.

1939-4551
100493
Arasi, Stefania
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Nurmatov, Ulugbek
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Turner, Paul J
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Ansotegui, Ignacio J
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Daher, Shahd
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Dunn-Galvin, Audrey
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Ebisawa, Motohiro
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Eigenmann, Philippe
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Fernandez-Rivas, Montserrat
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Gupta, Ruchi
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Nowak-Wegrzyn, Anna
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Petrou, Stavros
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Roberts, Graham
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Sánchez Borges, Mario A
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Sindher, Sayantani B
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Tanno, Luciana Kase
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Vazquez-Ortiz, Marta
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Vickery, Brian P
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Wong, Gary Wing-Kin
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Fiocchi, Alessandro
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Arasi, Stefania
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Nurmatov, Ulugbek
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Turner, Paul J
22cee218-a226-4300-aad1-b9a77ca65915
Ansotegui, Ignacio J
414b20b6-c4d0-4801-bbe1-b12f67a97ede
Daher, Shahd
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Dunn-Galvin, Audrey
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Ebisawa, Motohiro
874c6f29-2460-4d70-b0d0-5054b5ba0f71
Eigenmann, Philippe
3e63730f-7e33-412f-9e2d-64d607922647
Fernandez-Rivas, Montserrat
08303b54-d9ca-4622-8402-3a45eb37e022
Gupta, Ruchi
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Nowak-Wegrzyn, Anna
661bfdbf-32de-4421-9c1b-277c7b62861b
Petrou, Stavros
5ee930f5-99db-4fb8-b401-95584cff0e20
Roberts, Graham
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Sánchez Borges, Mario A
80ada54f-4b4e-40ad-afb6-f2083d65b246
Sindher, Sayantani B
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Tanno, Luciana Kase
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Vazquez-Ortiz, Marta
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Vickery, Brian P
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Wong, Gary Wing-Kin
a447817e-57a7-46a3-97a0-45abd059f3f8
Fiocchi, Alessandro
84f49387-5e31-4760-93d2-65b552d43c57

Arasi, Stefania, Nurmatov, Ulugbek, Turner, Paul J, Ansotegui, Ignacio J, Daher, Shahd, Dunn-Galvin, Audrey, Ebisawa, Motohiro, Eigenmann, Philippe, Fernandez-Rivas, Montserrat, Gupta, Ruchi, Nowak-Wegrzyn, Anna, Petrou, Stavros, Roberts, Graham, Sánchez Borges, Mario A, Sindher, Sayantani B, Tanno, Luciana Kase, Vazquez-Ortiz, Marta, Vickery, Brian P, Wong, Gary Wing-Kin and Fiocchi, Alessandro (2020) Consensus on DEfinition of Food Allergy SEverity (DEFASE): protocol for a systematic review. World Allergy Organization Journal, 13 (12), 100493. (doi:10.1016/j.waojou.2020.100493).

Record type: Review

Abstract

Background and aims: The term "Food Allergy" refers to a complex global health problem with a wide spectrum of severity. However, a uniform definition of severe food allergy is currently missing. This systematic review is the preliminary step towards a state-of-the-art synopsis of the current evidence relating to the severity of IgE-mediated food allergy; it will inform attempts to develop a consensus to define food allergy severity by clinicians and other stakeholders.

Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published studies. Studies will be independently screened against pre-defined eligibility criteria and critically appraised by established instruments. Data will be descriptively and, if possible and applicable, quantitatively synthesised.

Ethics and dissemination: This study does not require any specific ethical approval since it is a systematic review. We plan to report results from this systematic review in a peer reviewed journal. These results will be used to inform the development of an international consensus to define severe food allergy. Author's potential conflicts of interest are clearly stated.

PROSPERO registration number: CRD42020183103.

Text
Consensus on DEfinition - Version of Record
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More information

Accepted/In Press date: 18 December 2020
e-pub ahead of print date: 19 December 2020
Additional Information: © 2020 Published by Elsevier Inc. on behalf of World Allergy Organization.

Identifiers

Local EPrints ID: 446016
URI: http://eprints.soton.ac.uk/id/eprint/446016
ISSN: 1939-4551
PURE UUID: c81c86d3-58c9-4a66-8426-fb5a2b019f4a
ORCID for Graham Roberts: ORCID iD orcid.org/0000-0003-2252-1248

Catalogue record

Date deposited: 19 Jan 2021 17:30
Last modified: 28 Apr 2022 01:54

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Contributors

Author: Stefania Arasi
Author: Ulugbek Nurmatov
Author: Paul J Turner
Author: Ignacio J Ansotegui
Author: Shahd Daher
Author: Audrey Dunn-Galvin
Author: Motohiro Ebisawa
Author: Philippe Eigenmann
Author: Montserrat Fernandez-Rivas
Author: Ruchi Gupta
Author: Anna Nowak-Wegrzyn
Author: Stavros Petrou
Author: Graham Roberts ORCID iD
Author: Mario A Sánchez Borges
Author: Sayantani B Sindher
Author: Luciana Kase Tanno
Author: Marta Vazquez-Ortiz
Author: Brian P Vickery
Author: Gary Wing-Kin Wong
Author: Alessandro Fiocchi

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