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Weaning oxygen in infants with bronchopulmonary dysplasia

Weaning oxygen in infants with bronchopulmonary dysplasia
Weaning oxygen in infants with bronchopulmonary dysplasia
Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease commonly seen in preterm infants as the sequelae following respiratory distress syndrome. The management of evolving BPD aims to minimise lung injury and prevent the impact of hypoxia and hyperoxia. Proposed morbidities include respiratory instability, pulmonary hypertension, suboptimal growth, altered cerebral oxygenation and long-term neurodevelopmental impairment. The ongoing management and associated morbidity present a significant burden for carers and healthcare systems. Long-term oxygen therapy may be required for variable duration, though there is a lack of consensus and wide variation in practise when weaning supplemental oxygen. Furthermore, a shift in care towards earlier discharge and community care underlines the importance of a structured discharge and weaning process that eliminates the potential risks associated with hypoxia and hyperoxia. This review article describes recent evidence outlining oxygen saturation reference ranges in young infants, on which structured guidance can be based.
1526-0550
Everitt, Lucy
54d312d4-d7e6-4d4b-8502-33fba3c35a49
Awoseyila, A
99053065-7f16-4a9c-849f-c46140788c8c
Bhatt, Jayesh
07c31bf2-e9d9-42c2-b487-f7b3d9d90af2
Johnson, Mark John
64135487-45a1-46a6-a34b-595143e3c9a6
Vollmer, Brigitte
044f8b55-ba36-4fb2-8e7e-756ab77653ba
Evans, Hazel
7bcf2df5-0362-4456-9976-eb99f71b172f
Everitt, Lucy
54d312d4-d7e6-4d4b-8502-33fba3c35a49
Awoseyila, A
99053065-7f16-4a9c-849f-c46140788c8c
Bhatt, Jayesh
07c31bf2-e9d9-42c2-b487-f7b3d9d90af2
Johnson, Mark John
64135487-45a1-46a6-a34b-595143e3c9a6
Vollmer, Brigitte
044f8b55-ba36-4fb2-8e7e-756ab77653ba
Evans, Hazel
7bcf2df5-0362-4456-9976-eb99f71b172f

Everitt, Lucy, Awoseyila, A, Bhatt, Jayesh, Johnson, Mark John, Vollmer, Brigitte and Evans, Hazel (2020) Weaning oxygen in infants with bronchopulmonary dysplasia. Paediatric Respiratory Reviews, S1526-0542 (20). (doi:10.1016/j.prrv.2020.10.005).

Record type: Article

Abstract

Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease commonly seen in preterm infants as the sequelae following respiratory distress syndrome. The management of evolving BPD aims to minimise lung injury and prevent the impact of hypoxia and hyperoxia. Proposed morbidities include respiratory instability, pulmonary hypertension, suboptimal growth, altered cerebral oxygenation and long-term neurodevelopmental impairment. The ongoing management and associated morbidity present a significant burden for carers and healthcare systems. Long-term oxygen therapy may be required for variable duration, though there is a lack of consensus and wide variation in practise when weaning supplemental oxygen. Furthermore, a shift in care towards earlier discharge and community care underlines the importance of a structured discharge and weaning process that eliminates the potential risks associated with hypoxia and hyperoxia. This review article describes recent evidence outlining oxygen saturation reference ranges in young infants, on which structured guidance can be based.

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YPRRV_1438 (2) proof - Accepted Manuscript
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e-pub ahead of print date: 6 November 2020

Identifiers

Local EPrints ID: 446617
URI: http://eprints.soton.ac.uk/id/eprint/446617
ISSN: 1526-0550
PURE UUID: 03f7931b-c6f3-40f0-b5bd-88e69883a4f3
ORCID for Brigitte Vollmer: ORCID iD orcid.org/0000-0003-4088-5336

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Date deposited: 16 Feb 2021 17:32
Last modified: 26 Nov 2021 06:36

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Contributors

Author: Lucy Everitt
Author: A Awoseyila
Author: Jayesh Bhatt
Author: Mark John Johnson
Author: Hazel Evans

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