The University of Southampton
University of Southampton Institutional Repository

Endolymphatic hydrops in asymptomatic ears in unilateral Meniere's disease

Friedrichs, Ilka and Thornton, Arthur R. (2001) Endolymphatic hydrops in asymptomatic ears in unilateral Meniere's disease The Laryngoscope, 111, (5), pp. 857-860. (doi:10.1097/00005537-200105000-00019).

Record type: Article


Objectives/hypothesis: the aim of our study was the objective assessment of endolymphatic hydrops in asymptomatic ears in unilateral Meniere's disease with a noninvasive electrophysiological test and investigation of significant clinical signs. The null hypothesis was that there would be no signs of endolymphatic hydrops in the asymptomatic ear. Study design: prospective study using the traveling wave velocity test for endolymphatic hydrops. METHODS: The traveling wave velocity test was used in conjunction with standard audiological tests to investigate both ears of 181 Meniere's patients attending the Medical Research Council Institute of Hearing Research in Southampton, United Kingdom. The test uses derived auditory brainstem responses to estimate the velocity of the cochlear traveling wave that is altered in endolymphatic hydrops. Meniere's disease was assessed using Arenberg's five staging criteria. Significant correlations were evaluated using standard statistical methods. Results: of 100 patients with clinically unilateral Meniere's disease, 27% showed evidence of endolymphatic hydrops in their asymptomatic ear. There was a significant correlation between signs of hydrops and the mean air-conduction threshold at 500 Hz. Conclusions: we recommend that a full assessment of incipient disease in the asymptomatic ear in unilateral Meniere's disease should be undertaken before offering any treatment options to patients. Any suspicion of early disease in the asymptomatic ear in unilateral Meniere's disease should lead to full electrophysiological assessment to assess the evidence of endolymphatic hydrops in that ear

PDF 00005537-200105000-00019.pdf - Version of Record
Restricted to Repository staff only
Download (67kB)

More information

Published date: May 2001
Keywords: unilateral ménière’s disease, endolymphatic hydrops, traveling wave velocity, noninvasive, objective test of endolymphatic hydrops


Local EPrints ID: 44707
ISSN: 0023-852X
PURE UUID: 76288b65-f7d4-4b2b-bbce-5401eeeccb81

Catalogue record

Date deposited: 09 Mar 2007
Last modified: 17 Jul 2017 15:13

Export record



Author: Ilka Friedrichs
Author: Arthur R. Thornton

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.