Modelling in tumour biology part 1: Modelling concepts and structures
Modelling in tumour biology part 1: Modelling concepts and structures
Our strategies for the treatment of cancer are constrained by our incomplete understanding of tumour biology and behaviour, and by the enormous complexity and resilience to therapeutic perturbation found in the biological world. We are obliged to simplify this complexity through the use of models and mechanistic explanations. In the first of these papers, we consider the nature of modelling mechanisms available to clinical researchers and the extent to which we rely upon them in our understanding of the nature and behaviour of tumours. In the second part, we will consider specifically how models help us to develop more effective strategies for cancer therapy. (C) 2000 Harcourt Publishers Ltd.
87-94
Rew, D. A.
36dcc3ad-2379-4b61-a468-5c623d796887
February 2000
Rew, D. A.
36dcc3ad-2379-4b61-a468-5c623d796887
Rew, D. A.
(2000)
Modelling in tumour biology part 1: Modelling concepts and structures.
European Journal of Surgical Oncology, 26 (1), .
(doi:10.1053/ejso.1999.0747).
Abstract
Our strategies for the treatment of cancer are constrained by our incomplete understanding of tumour biology and behaviour, and by the enormous complexity and resilience to therapeutic perturbation found in the biological world. We are obliged to simplify this complexity through the use of models and mechanistic explanations. In the first of these papers, we consider the nature of modelling mechanisms available to clinical researchers and the extent to which we rely upon them in our understanding of the nature and behaviour of tumours. In the second part, we will consider specifically how models help us to develop more effective strategies for cancer therapy. (C) 2000 Harcourt Publishers Ltd.
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Published date: February 2000
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Local EPrints ID: 447223
URI: http://eprints.soton.ac.uk/id/eprint/447223
ISSN: 0748-7983
PURE UUID: a0bc1021-9817-4b80-8f69-42ac7a850d74
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Date deposited: 05 Mar 2021 17:30
Last modified: 17 Mar 2024 03:56
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