Novel negative pressure wound therapy with instillation and the management of diabetic foot infections
Novel negative pressure wound therapy with instillation and the management of diabetic foot infections
Purpose of review
The use of negative pressure wound therapy with instillation (NPWTi) in complex or difficult-to-treat acute and chronic wounds has expanded rapidly since the introduction of commercially available NPWTi systems. We summarize the evidence related to NPWTi and particularly focus on the application of this technology in diabetic foot ulcers, diabetic foot infections and postoperative diabetic wounds.
Recent findings
The benefits of negative pressure wound therapy (NPWT) are well documented in the treatment of complex acute and chronic wounds, including noninfected postoperative diabetic wounds and diabetic foot ulcers. Combining intermittent wound irrigation with NPWT may offer additional benefits compared to NPWT alone, including further reduction of wound bed bioburden, increased granulation tissue formation and provision of wound irrigation in a sealed environment, thus preventing potential cross-contamination events. Recently, available evidence suggests that adjunctive NPWTi may be superior to standard NPWT in the management of diabetic infections following surgical debridement and may promote granulation tissue formation in slow-to-heal wounds.
Summary
Available evidence relating to the utilization of NPWTi in diabetic foot infections is promising but limited in quality, being derived mostly from case series or small retrospective or prospective studies. In order to confirm or refute the potential benefits of NPWTi in this patient cohort, well designed randomized controlled studies are required that compare NPWTi to NPWT or standard wound care methodologies.
Diabetes, Diabetic foot, Diabetic foot infections, Negative pressure wound therapy, Negative pressure wound therapy with instillation
151-157
Dale, Adam P.
5096a630-1d0b-4e37-a1d4-e971e08acb54
Saeed, Kordo
87cb67e5-71e8-4759-bf23-2ea00ebd8b39
7 April 2015
Dale, Adam P.
5096a630-1d0b-4e37-a1d4-e971e08acb54
Saeed, Kordo
87cb67e5-71e8-4759-bf23-2ea00ebd8b39
Dale, Adam P. and Saeed, Kordo
(2015)
Novel negative pressure wound therapy with instillation and the management of diabetic foot infections.
Current Opinion in Infectious Diseases, 28 (2), .
(doi:10.1097/QCO.0000000000000146).
Abstract
Purpose of review
The use of negative pressure wound therapy with instillation (NPWTi) in complex or difficult-to-treat acute and chronic wounds has expanded rapidly since the introduction of commercially available NPWTi systems. We summarize the evidence related to NPWTi and particularly focus on the application of this technology in diabetic foot ulcers, diabetic foot infections and postoperative diabetic wounds.
Recent findings
The benefits of negative pressure wound therapy (NPWT) are well documented in the treatment of complex acute and chronic wounds, including noninfected postoperative diabetic wounds and diabetic foot ulcers. Combining intermittent wound irrigation with NPWT may offer additional benefits compared to NPWT alone, including further reduction of wound bed bioburden, increased granulation tissue formation and provision of wound irrigation in a sealed environment, thus preventing potential cross-contamination events. Recently, available evidence suggests that adjunctive NPWTi may be superior to standard NPWT in the management of diabetic infections following surgical debridement and may promote granulation tissue formation in slow-to-heal wounds.
Summary
Available evidence relating to the utilization of NPWTi in diabetic foot infections is promising but limited in quality, being derived mostly from case series or small retrospective or prospective studies. In order to confirm or refute the potential benefits of NPWTi in this patient cohort, well designed randomized controlled studies are required that compare NPWTi to NPWT or standard wound care methodologies.
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More information
Published date: 7 April 2015
Additional Information:
Publisher Copyright:
Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
Keywords:
Diabetes, Diabetic foot, Diabetic foot infections, Negative pressure wound therapy, Negative pressure wound therapy with instillation
Identifiers
Local EPrints ID: 447362
URI: http://eprints.soton.ac.uk/id/eprint/447362
ISSN: 0951-7375
PURE UUID: bd66423b-d059-4b3e-bf3b-c0baf0a70bdf
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Date deposited: 10 Mar 2021 17:34
Last modified: 17 Mar 2024 03:56
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Contributors
Author:
Adam P. Dale
Author:
Kordo Saeed
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