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How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC)

How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC)
How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC)

Novel rapid diagnostic tests (RDTs) offer huge potential to optimise clinical care and improve patient outcomes. In this study, we aim to assess the current patterns of use around the world, identify issues for successful implementation and suggest best practice advice on how to introduce new tests. An electronic survey was devised by the International Society of Antimicrobial Chemotherapy (ISAC) Rapid Diagnostics and Biomarkers working group focussing on the availability, structure and impact of RDTs around the world. It was circulated to ISAC members in December 2019. Results were collated according to the UN human development index (HDI). 81 responses were gathered from 31 different countries. 84% of institutions reported the availability of any test 24/7. In more developed countries, this was more for respiratory viruses, whereas in high and medium/low developed countries, it was for HIV and viral hepatitis. Only 37% of those carrying out rapid tests measured the impact. There is no ‘one-size fits all’ solution to RDTs: the requirements must be tailored to the healthcare setting in which they are deployed and there are many factors that should be considered prior to this.

Clinical governance, Infection, Microbiology, POCT, Point of care, Rapid diagnosis
0934-9723
429-434
Poole, Stephen
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Townsend, Jennifer
99f6cd8a-f09a-43a0-9542-72bbd9f7a425
Wertheim, Heiman
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Kidd, Stephen P.
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Welte, Tobias
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Schuetz, Philipp
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Luyt, Charles Edouard
37b0a767-fa7d-453c-a0c9-ca546e4430cd
Beishuizen, Albertus
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Jensen, Jens Ulrik Stæhr
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del Castillo, Juan González
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Plebani, Mario
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Saeed, Kordo
87cb67e5-71e8-4759-bf23-2ea00ebd8b39
Poole, Stephen
440d7904-ab72-469c-892b-c910cd1cb19b
Townsend, Jennifer
99f6cd8a-f09a-43a0-9542-72bbd9f7a425
Wertheim, Heiman
29bb2ded-495a-472a-b573-03f5df0c2302
Kidd, Stephen P.
1409c55c-35d2-4a0b-8ef2-2370e6bf1dee
Welte, Tobias
6607095c-9471-4022-b144-f683c6ac8f58
Schuetz, Philipp
ad48627c-d757-419c-bda1-a44b620bdd25
Luyt, Charles Edouard
37b0a767-fa7d-453c-a0c9-ca546e4430cd
Beishuizen, Albertus
0403a954-d9f1-4254-b35f-a50efb7345b7
Jensen, Jens Ulrik Stæhr
10252f2a-a577-49dd-a8cd-385070455a29
del Castillo, Juan González
e23c54eb-1eb6-4154-944e-baeaf38cdeb3
Plebani, Mario
748a0f7b-ca3c-49c8-96a8-e339562d2a9e
Saeed, Kordo
87cb67e5-71e8-4759-bf23-2ea00ebd8b39

Poole, Stephen, Townsend, Jennifer, Wertheim, Heiman, Kidd, Stephen P., Welte, Tobias, Schuetz, Philipp, Luyt, Charles Edouard, Beishuizen, Albertus, Jensen, Jens Ulrik Stæhr, del Castillo, Juan González, Plebani, Mario and Saeed, Kordo (2021) How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC). European Journal of Clinical Microbiology and Infectious Diseases, 40 (2), 429-434. (doi:10.1007/s10096-020-04031-2).

Record type: Article

Abstract

Novel rapid diagnostic tests (RDTs) offer huge potential to optimise clinical care and improve patient outcomes. In this study, we aim to assess the current patterns of use around the world, identify issues for successful implementation and suggest best practice advice on how to introduce new tests. An electronic survey was devised by the International Society of Antimicrobial Chemotherapy (ISAC) Rapid Diagnostics and Biomarkers working group focussing on the availability, structure and impact of RDTs around the world. It was circulated to ISAC members in December 2019. Results were collated according to the UN human development index (HDI). 81 responses were gathered from 31 different countries. 84% of institutions reported the availability of any test 24/7. In more developed countries, this was more for respiratory viruses, whereas in high and medium/low developed countries, it was for HIV and viral hepatitis. Only 37% of those carrying out rapid tests measured the impact. There is no ‘one-size fits all’ solution to RDTs: the requirements must be tailored to the healthcare setting in which they are deployed and there are many factors that should be considered prior to this.

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Accepted/In Press date: 27 August 2020
e-pub ahead of print date: 9 September 2020
Published date: February 2021
Additional Information: Publisher Copyright: © 2020, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
Keywords: Clinical governance, Infection, Microbiology, POCT, Point of care, Rapid diagnosis

Identifiers

Local EPrints ID: 447525
URI: http://eprints.soton.ac.uk/id/eprint/447525
ISSN: 0934-9723
PURE UUID: 7411e5e3-a9e8-4916-980b-e77e01b43160
ORCID for Kordo Saeed: ORCID iD orcid.org/0000-0003-0123-0302

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Date deposited: 15 Mar 2021 17:31
Last modified: 18 Mar 2024 03:52

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Contributors

Author: Stephen Poole
Author: Jennifer Townsend
Author: Heiman Wertheim
Author: Stephen P. Kidd
Author: Tobias Welte
Author: Philipp Schuetz
Author: Charles Edouard Luyt
Author: Albertus Beishuizen
Author: Jens Ulrik Stæhr Jensen
Author: Juan González del Castillo
Author: Mario Plebani
Author: Kordo Saeed ORCID iD

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