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Developments in tandem ion mobility mass spectrometry

Developments in tandem ion mobility mass spectrometry
Developments in tandem ion mobility mass spectrometry
Ion Mobility (IM) coupled to mass spectrometry (MS) is a useful tool for separating species of interest out of small quantities of heterogenous mixtures via a combination of m/z and molecular shape. While tandem MS instruments are common, instruments which employ tandem IM are less so with the first commercial IM–MS instrument capable of multiple IM selection rounds being released in 2019. Here we explore the history of tandem IM instruments, recent developments, the applications to biological systems and expected future directions.
0300-5127
2457–2466
Eldrid, Charles
caf78c85-1eae-4700-814a-01b5f0635a0b
Thalassinos, Konstantinos
75b3f786-6a27-420a-8727-97eafb34c022
Eldrid, Charles
caf78c85-1eae-4700-814a-01b5f0635a0b
Thalassinos, Konstantinos
75b3f786-6a27-420a-8727-97eafb34c022

Eldrid, Charles and Thalassinos, Konstantinos (2020) Developments in tandem ion mobility mass spectrometry. Biochemical Society Transactions, 48 (6), 2457–2466. (doi:10.1042/BST20190788).

Record type: Article

Abstract

Ion Mobility (IM) coupled to mass spectrometry (MS) is a useful tool for separating species of interest out of small quantities of heterogenous mixtures via a combination of m/z and molecular shape. While tandem MS instruments are common, instruments which employ tandem IM are less so with the first commercial IM–MS instrument capable of multiple IM selection rounds being released in 2019. Here we explore the history of tandem IM instruments, recent developments, the applications to biological systems and expected future directions.

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Accepted/In Press date: 17 November 2020
Published date: 18 December 2020

Identifiers

Local EPrints ID: 447813
URI: http://eprints.soton.ac.uk/id/eprint/447813
DOI: doi:10.1042/BST20190788
ISSN: 0300-5127
PURE UUID: 65fe08d6-6776-4c65-81a0-67e5ddc93077
ORCID for Charles Eldrid: ORCID iD orcid.org/0000-0001-5306-3644

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Date deposited: 23 Mar 2021 17:36
Last modified: 16 Mar 2024 10:53

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Contributors

Author: Charles Eldrid ORCID iD
Author: Konstantinos Thalassinos

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