The University of Southampton
University of Southampton Institutional Repository

The cognitive behavioural model of irritable bowel syndrome: a prospective investigation of gastroenteritis patients.

Spence, Meagan J. and Moss-Morris, Rona (2007) The cognitive behavioural model of irritable bowel syndrome: a prospective investigation of gastroenteritis patients. Gut, 56, (8), pp. 1066-1071. (doi:10.1136/gut.2006.108811).

Record type: Article


Background and aims: The aim of this study was to determine whether a combination of mood and personality factors together with illness beliefs and behaviours predict the onset of irritable bowel syndrome (IBS) post gastroenteritis, as suggested by the cognitive behavioural model of IBS.
Methods: Primary care patients with a positive test for Campylobacter gastroenteritis, and no previous history of IBS or serious bowel conditions were recruited into this prospective study (N=620). Participants completed a questionnaire at the time of infection which included standardised measures of mood, perceived stress, perfectionism, negative illness beliefs and illness behaviours. 3 and 6 months after initial infection, participants completed follow-up questionnaires designed to determine whether they met Rome criteria for IBS.
Results: A total of 49 participants met criteria for IBS at both follow-up points. Logistic regressions indicated that those who developed IBS had significantly higher levels of perceived stress (1.10 [95%CI, 1.02- 1.15]), anxiety (1.14 [95%CI, 1.05-1.23]), somatisation, (1.17 [95%CI, 1.02-1.35]), and negative illness beliefs (1.14 [95%CI, 1.03-1.27]) at the time of infection than those who did not develop IBS. IBS cases were also significantly more likely to remain active in the face of their acute symptoms until they felt forced to rest (all-or-nothing behaviour) (1.09 [95%CI, 1.03-1.16]), and significantly less likely to initially rest in response to their acute illness (0.93 [95%CI, .88- .97]). Depression and perfectionism were not associated with IBS onset.

Full text not available from this repository.

More information

Published date: August 2007
Keywords: biopsychosocial, campylobacter gastroenteritis, cognitive behavioural, functional somatic syndromes, irritable bowel syndrome


Local EPrints ID: 44799
ISSN: 0017-5749
PURE UUID: 1b658bde-4bd0-4df2-a604-95f073204be2

Catalogue record

Date deposited: 15 Mar 2007
Last modified: 17 Jul 2017 15:13

Export record



Author: Meagan J. Spence
Author: Rona Moss-Morris

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.