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Utility of Donor Corneoscleral Rim Cultures Performed Routinely Following Penetrating Keratoplasty

Utility of Donor Corneoscleral Rim Cultures Performed Routinely Following Penetrating Keratoplasty
Utility of Donor Corneoscleral Rim Cultures Performed Routinely Following Penetrating Keratoplasty
Purpose: To identify whether positive donor corneoscleral rim culture is associated with post-keratoplasty ocular infection.
Method: A retrospective study based on the bacterial microbiology culture data for all donor corneoscleral rims sent between 1999 and 2006 following keratoplasty at a university hospital in the UK. The sample size was 111 corneoscleral rims. This has been the routine practice to monitor sterility.
Results: The recipient donor cornea had a mean age of 78.3 years, with a range of 15 to 92 years, and a sex ratio of 41.7% males and 58.3% females. The corneal grafts took place between June 1999 and March 2006, with mean corneal graft size of 6.6 mm diameter and a range of 3 to 12 mm. The corneal donor age had a mean of 61.6 years and range of 12 to 97 years, with the death to enucleation time having a mean of 15 hours, with a range of 3 to 33 hours and a mean total donor corneal storage time of 21 days, with a range of 13 to 32 days. Positive bacterial cultures were reported in 5 donor corneoscleral rims, which were all found to have a corneal storage time greater than or equal to 15 days and death to enucleation time greater than or equal to 7 hours. No positive cultures were related to post-kerato-plasty infectious episodes and similarly no post-keratoplasty infectious episodes were related to positive cultures.
Conclusion: This study shows that donor corneal rim cultures are not useful for assisting with treating post-operative ocular infection as none of those with suspected post-keratoplasty ocular infection had a positive donor corneoscleral rim culture, and conversely none of those with a positive donor corneoscleral rim cultures had an ocular infection.
1442-6404
A138
Thiagarajan, M.
1480381b-0b88-4312-a31f-5da6875463c3
Hossain, Parwez
563de5fc-84ad-4539-9228-bde0237eaf51
Thiagarajan, M.
1480381b-0b88-4312-a31f-5da6875463c3
Hossain, Parwez
563de5fc-84ad-4539-9228-bde0237eaf51

Thiagarajan, M. and Hossain, Parwez (2008) Utility of Donor Corneoscleral Rim Cultures Performed Routinely Following Penetrating Keratoplasty. Clinical & Experimental Ophthalmology, 36 (suppl 1), A138. (doi:10.1111/j.1442-9071.2008.01748.x).

Record type: Meeting abstract

Abstract

Purpose: To identify whether positive donor corneoscleral rim culture is associated with post-keratoplasty ocular infection.
Method: A retrospective study based on the bacterial microbiology culture data for all donor corneoscleral rims sent between 1999 and 2006 following keratoplasty at a university hospital in the UK. The sample size was 111 corneoscleral rims. This has been the routine practice to monitor sterility.
Results: The recipient donor cornea had a mean age of 78.3 years, with a range of 15 to 92 years, and a sex ratio of 41.7% males and 58.3% females. The corneal grafts took place between June 1999 and March 2006, with mean corneal graft size of 6.6 mm diameter and a range of 3 to 12 mm. The corneal donor age had a mean of 61.6 years and range of 12 to 97 years, with the death to enucleation time having a mean of 15 hours, with a range of 3 to 33 hours and a mean total donor corneal storage time of 21 days, with a range of 13 to 32 days. Positive bacterial cultures were reported in 5 donor corneoscleral rims, which were all found to have a corneal storage time greater than or equal to 15 days and death to enucleation time greater than or equal to 7 hours. No positive cultures were related to post-kerato-plasty infectious episodes and similarly no post-keratoplasty infectious episodes were related to positive cultures.
Conclusion: This study shows that donor corneal rim cultures are not useful for assisting with treating post-operative ocular infection as none of those with suspected post-keratoplasty ocular infection had a positive donor corneoscleral rim culture, and conversely none of those with a positive donor corneoscleral rim cultures had an ocular infection.

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Published date: 18 July 2008

Identifiers

Local EPrints ID: 448143
URI: http://eprints.soton.ac.uk/id/eprint/448143
ISSN: 1442-6404
PURE UUID: 368e0c69-4caa-40d7-9ba8-079403f75e50
ORCID for Parwez Hossain: ORCID iD orcid.org/0000-0002-3131-2395

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Date deposited: 12 Apr 2021 16:47
Last modified: 17 Mar 2024 03:04

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Contributors

Author: M. Thiagarajan
Author: Parwez Hossain ORCID iD

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