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How to interpret a single cortisol measurement

How to interpret a single cortisol measurement
How to interpret a single cortisol measurement
Adrenal insufficiency can present with non-specific clinical features. Therefore, a single cortisol measurement is often included in the biochemical work-up of an unwell child. This article aims to review the diagnostic utility of a single cortisol measurement by outlining the physiological, clinical and technical factors affecting result interpretation. Clinical scenarios are used to illustrate how this test may be used in different commonly encountered situations in general paediatrics, with the aim of minimising the frequency of inconclusive results.

1743-0585
347-351
Davies, Justin
9f18fcad-f488-4c72-ac23-c154995443a9
Shaunak, Meera
8c081c66-eb60-47d2-83bb-6fa95933386d
Blair, Joanne
861084d4-b895-4e8d-a970-204dbf96b663
Davies, Justin
9f18fcad-f488-4c72-ac23-c154995443a9
Shaunak, Meera
8c081c66-eb60-47d2-83bb-6fa95933386d
Blair, Joanne
861084d4-b895-4e8d-a970-204dbf96b663

Davies, Justin, Shaunak, Meera and Blair, Joanne (2020) How to interpret a single cortisol measurement. Archives of Disease in Childhood: Education & Practice, 347-351. (doi:10.1136/archdischild-2019-318431).

Record type: Article

Abstract

Adrenal insufficiency can present with non-specific clinical features. Therefore, a single cortisol measurement is often included in the biochemical work-up of an unwell child. This article aims to review the diagnostic utility of a single cortisol measurement by outlining the physiological, clinical and technical factors affecting result interpretation. Clinical scenarios are used to illustrate how this test may be used in different commonly encountered situations in general paediatrics, with the aim of minimising the frequency of inconclusive results.

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Published date: 28 August 2020

Identifiers

Local EPrints ID: 448148
URI: http://eprints.soton.ac.uk/id/eprint/448148
ISSN: 1743-0585
PURE UUID: 07956869-4682-4ac9-b171-5a5a70ce0478

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Date deposited: 13 Apr 2021 16:30
Last modified: 27 Apr 2022 08:12

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Contributors

Author: Justin Davies
Author: Meera Shaunak
Author: Joanne Blair

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