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Nuclear spin relaxation of longitudinal and singlet order in liquid-CO2 solutions

Nuclear spin relaxation of longitudinal and singlet order in liquid-CO2 solutions
Nuclear spin relaxation of longitudinal and singlet order in liquid-CO2 solutions
Hyperpolarization techniques can enormously enhance the NMR signal thus allowing the exploitation of hyperpolarized substrates for in-vivo MRI applications. The short lifetime of hyperpolarized spin order poses significant limitations in such applications. Spin order storage can be prolonged through the use of long-lived spin states. Additionally, the storage of spin polarization–either in the form of longitudinal or singlet order–can be prolonged in low viscosity solutions. Here, we report the use of low viscosity liquid-CO 2 solutions to store nuclear spin polarization in the form of longitudinal and singlet order for extended periods. Our results demonstrate that this storage time can be considerably sustained in liquid-CO 2 solutions in comparison to other low viscosity solvents, opening up the possibility of new, exciting storage experiments in the future.
Nuclear Magnetic Resonance, Singlet Spin Order, liquid-CO2, long-lived spin states, nuclear spin relaxation
2296-2646
Moysiadi, Aliki
46fd11f7-a435-4f8e-83d7-5c9e3d98a737
Giustiniano, Francesco
f2692f6a-8f0a-49de-aa5d-7c2dff402545
Hall, Andrew M.R.
7188556b-d6e9-46a8-bf14-f9f4170edc0a
Cartlidge, Topaz Alaska Alice
f7afbdd8-5906-46d3-bd5f-454b706e8247
Brown, Lynda J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Pileio, Giuseppe
13f78e66-0707-4438-b9c9-6dbd3eb7d4e8
Moysiadi, Aliki
46fd11f7-a435-4f8e-83d7-5c9e3d98a737
Giustiniano, Francesco
f2692f6a-8f0a-49de-aa5d-7c2dff402545
Hall, Andrew M.R.
7188556b-d6e9-46a8-bf14-f9f4170edc0a
Cartlidge, Topaz Alaska Alice
f7afbdd8-5906-46d3-bd5f-454b706e8247
Brown, Lynda J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Pileio, Giuseppe
13f78e66-0707-4438-b9c9-6dbd3eb7d4e8

Moysiadi, Aliki, Giustiniano, Francesco, Hall, Andrew M.R., Cartlidge, Topaz Alaska Alice, Brown, Lynda J. and Pileio, Giuseppe (2021) Nuclear spin relaxation of longitudinal and singlet order in liquid-CO2 solutions. Frontiers in Chemistry, 9, [668044]. (doi:10.3389/fchem.2021.668044).

Record type: Article

Abstract

Hyperpolarization techniques can enormously enhance the NMR signal thus allowing the exploitation of hyperpolarized substrates for in-vivo MRI applications. The short lifetime of hyperpolarized spin order poses significant limitations in such applications. Spin order storage can be prolonged through the use of long-lived spin states. Additionally, the storage of spin polarization–either in the form of longitudinal or singlet order–can be prolonged in low viscosity solutions. Here, we report the use of low viscosity liquid-CO 2 solutions to store nuclear spin polarization in the form of longitudinal and singlet order for extended periods. Our results demonstrate that this storage time can be considerably sustained in liquid-CO 2 solutions in comparison to other low viscosity solvents, opening up the possibility of new, exciting storage experiments in the future.

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668044_Manuscript - Accepted Manuscript
Available under License Creative Commons Attribution.
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More information

Accepted/In Press date: 29 March 2021
Published date: 26 April 2021
Additional Information: Copyright © 2021 Moysiadi, Giustiniano, Hall, Cartlidge, Brown and Pileio.
Keywords: Nuclear Magnetic Resonance, Singlet Spin Order, liquid-CO2, long-lived spin states, nuclear spin relaxation

Identifiers

Local EPrints ID: 448221
URI: http://eprints.soton.ac.uk/id/eprint/448221
ISSN: 2296-2646
PURE UUID: c2d20bdd-abc2-450a-9a66-3aa542a5c6a6
ORCID for Francesco Giustiniano: ORCID iD orcid.org/0000-0001-9277-8538
ORCID for Lynda J. Brown: ORCID iD orcid.org/0000-0002-5678-0814
ORCID for Giuseppe Pileio: ORCID iD orcid.org/0000-0001-9223-3896

Catalogue record

Date deposited: 15 Apr 2021 16:32
Last modified: 28 Aug 2024 01:40

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Contributors

Author: Aliki Moysiadi
Author: Francesco Giustiniano ORCID iD
Author: Andrew M.R. Hall
Author: Topaz Alaska Alice Cartlidge
Author: Lynda J. Brown ORCID iD
Author: Giuseppe Pileio ORCID iD

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