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Data from: Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone

Data from: Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone
Data from: Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone
Studies investigating micromechanical properties in mouse cortical bone often solely focus on the mechanical behaviour along the long axis of the bone. Therefore, data on the anisotropy of mouse cortical bone is scarce. The aim of this study is the first-time evaluation of the anisotropy ratio between the longitudinal and transverse directions of reduced modulus and hardness in mouse femurs by using the nanoindentation technique. For this purpose, nine 22-week-old mice (C57BL/6) were sacrificed and all femurs extracted. A total of 648 indentations were performed with a Berkovich tip in the proximal (P), central (C) and distal (D) regions of the femoral shaft in the longitudinal and transverse directions. Higher values for reduced modulus are obtained for indentations in the longitudinal direction, with anisotropy ratios of 1.72 ± 0.40 (P), 1.75 ± 0.69 (C) and 1.34 ± 0.30 (D). Hardness is also higher in the longitudinal direction, with anisotropic ratios of 1.35 ± 0.27 (P), 1.35 ± 0.47 (C) and 1.17 ± 0.19 (D). We observed a significant anisotropy in the micromechanical properties of the mouse femur, but the correlation for reduced modulus and hardness between the two directions is low (r2,Load-depth curvesThe .zip file contains the load-depth curves of all indentations in .txt, .hys and .lfb format performed with the Hysitron TriboIndenter TI 900 (Hysitron Inc., Minneapolis, MN, USA). The data files were loaded, viewed and analyzed with the software provided with the indenter (TriboScan, Hysitron Inc., Minneapolis, MN, USA). The files are divided in two main folders. One folder contains all measurements performed in transverse direction (transverse) and the other contains all measurements in longitudinal direction (longitudinal). These folders contains subfolders named after the samples. They are subsequently divided in sub-subfolders, which contains a set of six indentations each. P: proximal region; C: central region; D: distal region. Mxx: mouse number and right or left femur (e.g. M1L: mouse no. 1, left femur).Load_depth_curves.zip,
DRYAD
Casanova, Michele
6fece42d-9268-4e0f-9c14-1b1b4d74961e
Balmelli, Anna
a35e6524-23d6-4c69-986c-bdd42048cbec
Carnelli, Davide
33ab1d18-1bb8-4239-b191-47ba22f18166
Courty, Diana
6d0b1a8f-b7ec-47fc-ba3c-25738b1694e2
Schneider, Philipp
a810f925-4808-44e4-8a4a-a51586f9d7ad
Müller, Ralph
c83a3760-2e7b-4e16-a8fe-1d9c538d7076
Casanova, Michele
6fece42d-9268-4e0f-9c14-1b1b4d74961e
Balmelli, Anna
a35e6524-23d6-4c69-986c-bdd42048cbec
Carnelli, Davide
33ab1d18-1bb8-4239-b191-47ba22f18166
Courty, Diana
6d0b1a8f-b7ec-47fc-ba3c-25738b1694e2
Schneider, Philipp
a810f925-4808-44e4-8a4a-a51586f9d7ad
Müller, Ralph
c83a3760-2e7b-4e16-a8fe-1d9c538d7076

Casanova, Michele, Balmelli, Anna, Courty, Diana and Müller, Ralph (2017) Data from: Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone. DRYAD doi:10.5061/dryad.h5p79 [Dataset]

Record type: Dataset

Abstract

Studies investigating micromechanical properties in mouse cortical bone often solely focus on the mechanical behaviour along the long axis of the bone. Therefore, data on the anisotropy of mouse cortical bone is scarce. The aim of this study is the first-time evaluation of the anisotropy ratio between the longitudinal and transverse directions of reduced modulus and hardness in mouse femurs by using the nanoindentation technique. For this purpose, nine 22-week-old mice (C57BL/6) were sacrificed and all femurs extracted. A total of 648 indentations were performed with a Berkovich tip in the proximal (P), central (C) and distal (D) regions of the femoral shaft in the longitudinal and transverse directions. Higher values for reduced modulus are obtained for indentations in the longitudinal direction, with anisotropy ratios of 1.72 ± 0.40 (P), 1.75 ± 0.69 (C) and 1.34 ± 0.30 (D). Hardness is also higher in the longitudinal direction, with anisotropic ratios of 1.35 ± 0.27 (P), 1.35 ± 0.47 (C) and 1.17 ± 0.19 (D). We observed a significant anisotropy in the micromechanical properties of the mouse femur, but the correlation for reduced modulus and hardness between the two directions is low (r2,Load-depth curvesThe .zip file contains the load-depth curves of all indentations in .txt, .hys and .lfb format performed with the Hysitron TriboIndenter TI 900 (Hysitron Inc., Minneapolis, MN, USA). The data files were loaded, viewed and analyzed with the software provided with the indenter (TriboScan, Hysitron Inc., Minneapolis, MN, USA). The files are divided in two main folders. One folder contains all measurements performed in transverse direction (transverse) and the other contains all measurements in longitudinal direction (longitudinal). These folders contains subfolders named after the samples. They are subsequently divided in sub-subfolders, which contains a set of six indentations each. P: proximal region; C: central region; D: distal region. Mxx: mouse number and right or left femur (e.g. M1L: mouse no. 1, left femur).Load_depth_curves.zip,

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Published date: 1 January 2017

Identifiers

Local EPrints ID: 448664
URI: http://eprints.soton.ac.uk/id/eprint/448664
PURE UUID: 6001b222-2532-43d7-82a5-5f3fc6a14cb5
ORCID for Philipp Schneider: ORCID iD orcid.org/0000-0001-7499-3576

Catalogue record

Date deposited: 29 Apr 2021 16:32
Last modified: 30 Apr 2021 01:45

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Contributors

Creator: Michele Casanova
Creator: Anna Balmelli
Contributor: Davide Carnelli
Creator: Diana Courty
Contributor: Philipp Schneider ORCID iD
Creator: Ralph Müller

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