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Medical algorithm: Early introduction of food allergens in high-risk populations

Medical algorithm: Early introduction of food allergens in high-risk populations
Medical algorithm: Early introduction of food allergens in high-risk populations

Oral Tolerance Induction (OTI) is the only RCT-proven effective intervention for preventing childhood food allergy.(1, 2) OTI to peanut is highly effective in a high-risk population with an 81% relative risk ration (RRR) to peanut allergy .(3) OTI also reduced egg allergy in the general population in a per protocol analysis.(1) These published RCT findings have changed practice and many governmental and allergy societies now recommend introducing peanut in infancy; some suggest that other foods, such as well-cooked egg, are also introduced. Only National Institute of Allergy and Infectious Diseases (NIAID) stratify their recommendations according to food allergy (FA) risk level.

allergy diagnosis, atopic dermatitis, challenge tests, complementary feeding, food allergy, pediatrics, prevention, weaning
0105-4538
1592-1594
Fisher, Helen R
0120c9ec-635f-4c74-9619-200842a2a39e
Lack, Gideon
cac030a2-c358-4880-a91d-d67d06e8e321
Roberts, Graham
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Bahnson, Henry T
2ecc6945-97fd-46bc-8d46-42606d4ccfe0
Du Toit, George
7930b820-e6f7-4c4c-866c-4334017d1106
Fisher, Helen R
0120c9ec-635f-4c74-9619-200842a2a39e
Lack, Gideon
cac030a2-c358-4880-a91d-d67d06e8e321
Roberts, Graham
ea00db4e-84e7-4b39-8273-9b71dbd7e2f3
Bahnson, Henry T
2ecc6945-97fd-46bc-8d46-42606d4ccfe0
Du Toit, George
7930b820-e6f7-4c4c-866c-4334017d1106

Fisher, Helen R, Lack, Gideon, Roberts, Graham, Bahnson, Henry T and Du Toit, George (2021) Medical algorithm: Early introduction of food allergens in high-risk populations. Allergy, 76 (5), 1592-1594. (doi:10.1111/all.14717).

Record type: Article

Abstract

Oral Tolerance Induction (OTI) is the only RCT-proven effective intervention for preventing childhood food allergy.(1, 2) OTI to peanut is highly effective in a high-risk population with an 81% relative risk ration (RRR) to peanut allergy .(3) OTI also reduced egg allergy in the general population in a per protocol analysis.(1) These published RCT findings have changed practice and many governmental and allergy societies now recommend introducing peanut in infancy; some suggest that other foods, such as well-cooked egg, are also introduced. Only National Institute of Allergy and Infectious Diseases (NIAID) stratify their recommendations according to food allergy (FA) risk level.

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More information

e-pub ahead of print date: 21 December 2020
Published date: May 2021
Additional Information: This article is protected by copyright. All rights reserved.
Keywords: allergy diagnosis, atopic dermatitis, challenge tests, complementary feeding, food allergy, pediatrics, prevention, weaning

Identifiers

Local EPrints ID: 449221
URI: http://eprints.soton.ac.uk/id/eprint/449221
ISSN: 0105-4538
PURE UUID: 3cca9993-904f-4626-9896-44eef1453fa7
ORCID for Graham Roberts: ORCID iD orcid.org/0000-0003-2252-1248

Catalogue record

Date deposited: 19 May 2021 18:20
Last modified: 26 Nov 2021 02:49

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Contributors

Author: Helen R Fisher
Author: Gideon Lack
Author: Graham Roberts ORCID iD
Author: Henry T Bahnson
Author: George Du Toit

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