The University of Southampton
University of Southampton Institutional Repository
Warning ePrints Soton is experiencing an issue with some file downloads not being available. We are working hard to fix this. Please bear with us.

Synthesis of Fe3O4/Ag nanohybrid ferrofluids and their applications as antimicrobial and antifibrotic agents

Synthesis of Fe3O4/Ag nanohybrid ferrofluids and their applications as antimicrobial and antifibrotic agents
Synthesis of Fe3O4/Ag nanohybrid ferrofluids and their applications as antimicrobial and antifibrotic agents
To date, the search for creating stable ferrofluids with excellent properties for biomedical application is one of the challenging scientific and practical investigations. In this study, novel Fe3O4/Ag nanohybrid ferrofluids from iron sand were synthesized using a double-layer method. The Fe3O4/Ag nanocomposites exhibited stable crystallite sizes of 11.8 12.1 nm and 36.8–37.2 nm for Fe3O4 and Ag, respectively. The lattice parameters of the spinel structure Fe3O4 and face-centered cubic Ag were respectively 8.344 Å and 4.091 Å. With increasing Ag amount, the crystallite phase of Ag in the nanocomposites increased from 40.2% to 77.2%. The XPS results confirmed that Fe3O4/Ag nanocomposites were successfully prepared, where Fe3O4 mixed well with Ag via strong ionic bonding. The FTIR results confirmed the presence of Fe3O4/Ag, oleic acid, and dimethyl sulfoxide as the filler, first layer, and second layer, respectively. The as-prepared ferrofluids exhibited superparamagnetic behavior, where the saturation magnetization decreased with increasing Ag content. The Fe3O4/Ag nanohybrid ferrofluids exhibited excellent antimicrobial performance against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Candida albicans. More importantly, the Fe3O4/Ag nanohybrid ferrofluids decreased the progression of liver fibrosis-related inflammation and fibrogenic activity on hepatic stellate cells.
2405-8440
Taufiq, Ahmad
efded88e-e3ab-4308-90b6-f838416b846f
Saputro, Rosy Eko
9880c2b1-5414-4248-919d-db6ca08add5a
Susanto, Hendra
74a99e0c-c16e-49a9-9f81-85c28196f186
Hidayat, Nurul
d4b83e44-5202-4ca3-b4cd-ee82fe5d8ba5
Sunaryono, Sunaryono
2cc8305c-2fd0-4b79-9524-25f126484f03
Amrillah, Tahta
4b5611ca-c0a2-49bc-b879-530ad9b1947b
Wijaya, Husni Wahyu
e8e1d364-b7d5-4d72-a1f6-5e5374e9af0d
Mufti, Nandang
f91a02d3-d6cf-46d3-ba99-ba130ab12248
Simanjuntak, Firman Mangasa
a5b8dd07-002c-4520-9f67-2dc20d2ff0d5
Taufiq, Ahmad
efded88e-e3ab-4308-90b6-f838416b846f
Saputro, Rosy Eko
9880c2b1-5414-4248-919d-db6ca08add5a
Susanto, Hendra
74a99e0c-c16e-49a9-9f81-85c28196f186
Hidayat, Nurul
d4b83e44-5202-4ca3-b4cd-ee82fe5d8ba5
Sunaryono, Sunaryono
2cc8305c-2fd0-4b79-9524-25f126484f03
Amrillah, Tahta
4b5611ca-c0a2-49bc-b879-530ad9b1947b
Wijaya, Husni Wahyu
e8e1d364-b7d5-4d72-a1f6-5e5374e9af0d
Mufti, Nandang
f91a02d3-d6cf-46d3-ba99-ba130ab12248
Simanjuntak, Firman Mangasa
a5b8dd07-002c-4520-9f67-2dc20d2ff0d5

Taufiq, Ahmad, Saputro, Rosy Eko, Susanto, Hendra, Hidayat, Nurul, Sunaryono, Sunaryono, Amrillah, Tahta, Wijaya, Husni Wahyu, Mufti, Nandang and Simanjuntak, Firman Mangasa (2020) Synthesis of Fe3O4/Ag nanohybrid ferrofluids and their applications as antimicrobial and antifibrotic agents. Heliyon, 6 (12), [e05813]. (doi:10.1016/j.heliyon.2020.e05813).

Record type: Article

Abstract

To date, the search for creating stable ferrofluids with excellent properties for biomedical application is one of the challenging scientific and practical investigations. In this study, novel Fe3O4/Ag nanohybrid ferrofluids from iron sand were synthesized using a double-layer method. The Fe3O4/Ag nanocomposites exhibited stable crystallite sizes of 11.8 12.1 nm and 36.8–37.2 nm for Fe3O4 and Ag, respectively. The lattice parameters of the spinel structure Fe3O4 and face-centered cubic Ag were respectively 8.344 Å and 4.091 Å. With increasing Ag amount, the crystallite phase of Ag in the nanocomposites increased from 40.2% to 77.2%. The XPS results confirmed that Fe3O4/Ag nanocomposites were successfully prepared, where Fe3O4 mixed well with Ag via strong ionic bonding. The FTIR results confirmed the presence of Fe3O4/Ag, oleic acid, and dimethyl sulfoxide as the filler, first layer, and second layer, respectively. The as-prepared ferrofluids exhibited superparamagnetic behavior, where the saturation magnetization decreased with increasing Ag content. The Fe3O4/Ag nanohybrid ferrofluids exhibited excellent antimicrobial performance against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Candida albicans. More importantly, the Fe3O4/Ag nanohybrid ferrofluids decreased the progression of liver fibrosis-related inflammation and fibrogenic activity on hepatic stellate cells.

Text
1-s2.0-S2405844020326566-main - Version of Record
Download (3MB)

More information

Accepted/In Press date: 18 December 2020
Published date: 29 December 2020

Identifiers

Local EPrints ID: 449271
URI: http://eprints.soton.ac.uk/id/eprint/449271
ISSN: 2405-8440
PURE UUID: a8507fc3-eca5-4cfe-a660-0ac6746d9676

Catalogue record

Date deposited: 21 May 2021 16:30
Last modified: 23 Aug 2021 16:56

Export record

Altmetrics

Contributors

Author: Ahmad Taufiq
Author: Rosy Eko Saputro
Author: Hendra Susanto
Author: Nurul Hidayat
Author: Sunaryono Sunaryono
Author: Tahta Amrillah
Author: Husni Wahyu Wijaya
Author: Nandang Mufti
Author: Firman Mangasa Simanjuntak

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×