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Cell and molecular mechanisms of pathogenesis and treatment of cancer

Cell and molecular mechanisms of pathogenesis and treatment of cancer
Cell and molecular mechanisms of pathogenesis and treatment of cancer

Surgery remains the mainstay of treatment for most classes of human solid tumours, with the principal exception of lymphomas, but it is insufficient in many cases to guarantee cure. With few exceptions, recurrent and metastatic solid tumours continue to defy attempts to develop effective adjuvant therapies. Recent insights into tumour biology reveal an increasingly complex picture of cell and molecular processes which confer heterogeneity and resistance to treatment upon tumours. These insights may also yield new targets for more effective adjuvant therapies.

Cancer, Cell biology, Drug resistance, Pathogenesis
0032-5473
77-88
Rew, David A.
36dcc3ad-2379-4b61-a468-5c623d796887
Rew, David A.
36dcc3ad-2379-4b61-a468-5c623d796887

Rew, David A. (1998) Cell and molecular mechanisms of pathogenesis and treatment of cancer. Postgraduate Medical Journal, 74 (868), 77-88. (doi:10.1136/pgmj.74.868.77).

Record type: Review

Abstract

Surgery remains the mainstay of treatment for most classes of human solid tumours, with the principal exception of lymphomas, but it is insufficient in many cases to guarantee cure. With few exceptions, recurrent and metastatic solid tumours continue to defy attempts to develop effective adjuvant therapies. Recent insights into tumour biology reveal an increasingly complex picture of cell and molecular processes which confer heterogeneity and resistance to treatment upon tumours. These insights may also yield new targets for more effective adjuvant therapies.

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More information

Published date: 1998
Keywords: Cancer, Cell biology, Drug resistance, Pathogenesis

Identifiers

Local EPrints ID: 449377
URI: http://eprints.soton.ac.uk/id/eprint/449377
ISSN: 0032-5473
PURE UUID: 07b5ec41-ad95-4aaf-9811-53e9b5114415
ORCID for David A. Rew: ORCID iD orcid.org/0000-0002-4518-2667

Catalogue record

Date deposited: 26 May 2021 16:32
Last modified: 17 Mar 2024 03:56

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